Gene Information gene info

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GENE：SATB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SATB1
FullNmae SATB homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10541
EnsembleID ENSG00000182568
Uniprot Q01826

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SATB1 apoptosis 29381393 SATB1 reprograms chromatin and transcription profiles to promote tumor cell growth and invasion and inhibit apoptosis, leading to tumor progression and metastasis. retulator signature

Go Annotation:

GeneSymbol Go id
SATB1 GO:0000122,GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0003690,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0006325,GO:0006338,GO:0006357,GO:0016363,GO:0016604,GO:0016605,GO:0043565

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SATB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SATB1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SATB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SATB1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SATB1 20554955 21743493 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SATB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EZH2 SATB1 21232178 trascriptional regulation,stimulation inferred by curator TFlink
TNFAIP3 SATB1 24039598 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002B2B5C SATB1 22683624 23542418 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00002B2B5C SATB1 22683624 23505378 23542418 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,northern blot,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000039A25B SATB1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000237AF9 SATB1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C3AC1 SATB1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000009262D SATB1 22227207 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase
URS00005E6F45 SATB1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 SATB1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 SATB1 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000140295 SATB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005E1A16 SATB1 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000027080C SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000610EFA SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001B968D SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000B7E30 SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000028DE3F SATB1 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CTBP1 SATB1 25361965 interaction type N/A PTMCode2
SATB1 CTBP1 25361965 interaction type N/A PTMCode2
CASP6 SATB1 25361965 interaction type N/A PTMCode2
SATB1 CASP6 25361965 interaction type N/A PTMCode2
SATB1 GATA3 25361965 interaction type N/A PTMCode2
GATA3 SATB1 25361965 interaction type N/A PTMCode2
KAT2B SATB1 25361965 interaction type N/A PTMCode2
SATB1 KAT2B 25361965 interaction type N/A PTMCode2
PML SATB1 25361965 interaction type N/A PTMCode2
SATB1 PML 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I SATB1 14525934 16189514 18408014 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
QPRT SATB1 25348397 N/A physical interaction ComPPI
FOXB1 SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXC2 SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
FOXG1 SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NFATC1 SATB1 25348397 N/A physical interaction ComPPI
JUN SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SUMO1 SATB1 18408014 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
EP300 SATB1 14525934 14605447 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PIAS1 SATB1 18408014 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CTBP1 SATB1 19103759 25348397 27898060 N/A physical interaction ComPPI,OmniPath
KAT2B SATB1 14525934 16630892 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CASP6 SATB1 11463840 14525934 18408014 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
SIN3A SATB1 25348397 N/A physical interaction ComPPI
UBR5 SATB1 25348397 N/A physical interaction ComPPI
NFATC2 SATB1 25348397 N/A physical interaction ComPPI
BAZ1A SATB1 25348397 N/A physical interaction,in vitro ComPPI
CBX4 SATB1 18408014 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TAL1 SATB1 25348397 N/A physical interaction ComPPI
TOPORS SATB1 18408014 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SPG21 SATB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HDAC2 SATB1 25348397 N/A physical interaction ComPPI
CTNNB1 SATB1 20126258 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
PIAS4 SATB1 18408014 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIRT1 SATB1 25348397 N/A physical interaction ComPPI
FOXA1 SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
ZMIZ1 SATB1 25348397 N/A physical interaction ComPPI
FOXE1 SATB1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PIAS3 SATB1 18408014 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SATB1 SMARCA5 25348397 N/A physical interaction,in vitro ComPPI
SATB1 MTA2 12374985 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SATB1 CUX1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SATB1 GATA3 14525934 17057718 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
SATB1 HDAC1 12374985 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SATB1 CUX1 10373541 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
SATB1 PML 17173041 18408014 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SATB1 CHD3 12374985 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SATB1 RBPJ 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 TEAD2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXC1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXD3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXF1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXN1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXO1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXP1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXP3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 FOXS1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
SATB1 P4HA3 25348397 N/A physical interaction ComPPI
SATB1 SUMO1P1 24234451 25348397 25416956 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SATB1 PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SATB1 IGF2BP1 19029303 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR2J SATB1 12036295 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
SATB1 SATB1 11463840 12374985 14525934 N/A experimental interaction detection,two hybrid HPRD
H1-5 SATB1 24234451 30021884 physical association cross-linking study IntAct
CASP6 SATB1 11463840 18408014 27898060 stimulant N/A OmniPath

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