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GENE：SMURF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SMURF1
FullNmae SMAD specific E3 ubiquitin protein ligase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16807
EnsembleID ENSG00000198742
Uniprot Q9HCE7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SMURF1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMURF1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
SMURF1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SMURF1 GO:0000209,GO:0004842,GO:0005160,GO:0005515,GO:0005543,GO:0005654,GO:0005737,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006511,GO:0006511,GO:0006611,GO:0007398,GO:0016567,GO:0030154,GO:0030424,GO:0030509,GO:0030512,GO:0030514,GO:0030514,GO:0030514,GO:0032801,GO:0032926,GO:0043025,GO:0043161,GO:0043161,GO:0045773,GO:0060071,GO:0061630,GO:0061630,GO:0061630,GO:0061736,GO:0061753,GO:0070062,GO:0070411,GO:0070412,GO:0070697,GO:0071211,GO:0072659,GO:0072659,GO:1903861,GO:2000060

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SMURF1 hsa:57154 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
SMURF1 hsa:57154 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
SMURF1 hsa:57154 path:hsa04144 Endocytosis - Homo sapiens (human)
SMURF1 hsa:57154 path:hsa04340 Hedgehog signaling pathway - Homo sapiens (human)
SMURF1 hsa:57154 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
SMURF1 hsa:57154 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMURF1 PARD6A 14657501 14722617 14744429 15265520 15761148 16472676 21572392 22949611 26192618 association N/A ACSN
CTHRC1 SMURF1 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
PRICKLE1 SMURF1 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
RACK1 SMURF1 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
ROR2 SMURF1 11226259 14657501 14704854 14722617 14744429 14747478 15265520 15265686 15618519 15761148 16263762 17127310 17884187 18497258 18851840 19020754 19379695 19565474 19853559 20006983 20930545 21087212 21397842 21572392 22017973 22949611 26192618 7641885 8655584 interaction type N/A ACSN
SMURF1 TGFBR1 12519765 12857866 14657019 14657501 14722617 14744429 15265520 15761148 21572392 22949611 23331499 26192618 interaction type,stimulation N/A ACSN,SignaLink
SMURF1 RHOA 14657501 14722617 14744429 15265520 15761148 16472676 21572392 22949611 26192618 interaction type N/A ACSN
SMURF1 SQSTM1 15761153 23180781 physical association luminescence based mammalian interactome mapping InnateDB
SMAD7 SMURF1 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMURF1 SMAD7 11278251 12151385 12408818 12519765 14722617 15221015 16720724 18988627 21071413 23180781 23331499 stimulation,physical association anti tag coimmunoprecipitation InnateDB,SignaLink,SignaLink
SMURF1 ACVR1B 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMURF1 FKBP1A 16720724 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMURF1 SMURF1 12519765 12738770 14701828 15817471 17317136 22298955 26467481 ubiquitination reaction,down-regulates,down-regulates activity,relocalization reaction N/A Signor
SMURF1 SMAD6 11278251 15123739 15221015 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
SMURF1 AXIN1 23959799 ubiquitination reaction,inhibition N/A SignaLink
SMURF1 SMAD3 10458166 15221015 23331499 stimulation N/A SignaLink
SMURF1 SMAD2 10458166 15221015 20207742 23331499 stimulation N/A SignaLink
SMURF1 SMAD5 12857866 14711801 15221015 18641638 23331499 interaction type N/A SignaLink
SMURF1 SMAD1 14701756 14711801 15221015 17289590 23331499 interaction type N/A SignaLink
KAT2A SMURF1 12408818 23331499 inhibition N/A SignaLink
PARD6A SMURF1 19114990 21262463 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
DVL2 SMURF1 20005715 interaction type N/A PSP
PAK1IP1 SMURF1 20005715 interaction type N/A PSP
RHPN2 SMURF1 20005715 interaction type N/A PSP
SQSTM1 SMURF1 20005715 interaction type N/A PSP
PAK1IP1 SMURF1 15761153 18988627 20005715 N/A N/A SignaLink
SQSTM1 SMURF1 20005715 N/A N/A SignaLink
DVL2 SMURF1 18988627 19379695 20005715 N/A N/A SignaLink
RHPN2 SMURF1 15761153 18988627 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 SMURF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SMURF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SMURF1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 SMURF1 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SMURF1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SMURF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C SMURF1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 SMURF1 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 SMURF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA SMURF1 21898695 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F0F49 SMURF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000007D64A SMURF1 24858688 25416803 mrna cleavage,inhibition western blot,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000041CB9C SMURF1 22473208 24435757 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS000040EE1D SMURF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 SMURF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 SMURF1 25416803 27214554 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
HNRNPK SMURF1 25348397 N/A physical interaction ComPPI
BYSL SMURF1 25348397 N/A physical interaction ComPPI
NUDT21 SMURF1 25348397 N/A physical interaction ComPPI
SNRPB SMURF1 25348397 N/A physical interaction ComPPI
CUL5 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RBM17 SMURF1 25348397 N/A physical interaction ComPPI
SNRPA SMURF1 25348397 N/A physical interaction ComPPI
DDX21 SMURF1 25348397 N/A physical interaction ComPPI
HSPA8 SMURF1 25348397 N/A physical interaction ComPPI
EIF3H SMURF1 25348397 N/A physical interaction ComPPI
OXSR1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LDHB SMURF1 25348397 N/A physical interaction ComPPI
VIM SMURF1 25348397 N/A physical interaction ComPPI
SNRPA1 SMURF1 25348397 N/A physical interaction ComPPI
PCBP1 SMURF1 25348397 N/A physical interaction ComPPI
TRIB3 SMURF1 25348397 N/A physical interaction ComPPI
CFL1 SMURF1 25348397 N/A physical interaction ComPPI
PPP2R1A SMURF1 25348397 N/A physical interaction ComPPI
PTS SMURF1 25348397 N/A physical interaction ComPPI
STAT1 SMURF1 25348397 N/A physical interaction ComPPI
TUBB SMURF1 25348397 N/A physical interaction ComPPI
GNG11 SMURF1 14525934 15761153 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
CLNS1A SMURF1 25348397 N/A physical interaction ComPPI
SNRPD1 SMURF1 25348397 N/A physical interaction ComPPI
VCP SMURF1 25348397 N/A physical interaction ComPPI
LMNA SMURF1 25348397 N/A physical interaction ComPPI
ACTB SMURF1 25348397 N/A physical interaction ComPPI
U2AF1L5 SMURF1 25348397 N/A physical interaction ComPPI
RPS15 SMURF1 25348397 N/A physical interaction ComPPI
UBE2D1 SMURF1 25348397 N/A physical interaction ComPPI
ROCK1 SMURF1 25348397 N/A physical interaction ComPPI
SMAD4 SMURF1 25348397 N/A physical interaction ComPPI
GTF2B SMURF1 25348397 N/A physical interaction ComPPI
JUNB SMURF1 20200942 25348397 27898060 N/A physical interaction ComPPI,OmniPath
TUFM SMURF1 25348397 N/A physical interaction ComPPI
EIF3E SMURF1 25348397 N/A physical interaction ComPPI
HNRNPH2 SMURF1 25348397 N/A physical interaction ComPPI
CSNK1D SMURF1 25348397 N/A physical interaction ComPPI
PADI4 SMURF1 25348397 N/A physical interaction ComPPI
PAK1 SMURF1 25348397 N/A in vivo ComPPI
SMURF2 SMURF1 25348397 N/A physical interaction ComPPI
ARHGAP5 SMURF1 25348397 N/A physical interaction ComPPI
SMAD1 SMURF1 14525934 14701756 15231748 15761153 19914168 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
BTK SMURF1 25348397 N/A physical interaction ComPPI
TGFBR2 SMURF1 25348397 N/A physical interaction ComPPI
OCLN SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMAD7 SMURF1 11278251 12151385 12519765 14525934 25348397 N/A experimental interaction detection,isothermal titration calorimetry,nuclear magnetic resonance,physical interaction,in vitro,in vivo,ion mobility mass spectrometry of complexes ComPPI,HPRD
PRKCA SMURF1 25348397 N/A physical interaction ComPPI
MATK SMURF1 25348397 N/A physical interaction ComPPI
LCK SMURF1 25348397 N/A physical interaction ComPPI
GDI2 SMURF1 25348397 N/A physical interaction ComPPI
RUNX2 SMURF1 16299379 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMAD2 SMURF1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMAD3 SMURF1 14525934 15231748 15761153 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
DHX9 SMURF1 25348397 N/A physical interaction ComPPI
SMAD5 SMURF1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SF3B1 SMURF1 25348397 N/A physical interaction ComPPI
FZR1 SMURF1 22152476 22949615 25348397 27898060 N/A physical interaction ComPPI,OmniPath
ITK SMURF1 25348397 N/A physical interaction ComPPI
UBE2G1 SMURF1 25348397 N/A physical interaction ComPPI
UBE2D2 SMURF1 25348397 N/A physical interaction ComPPI
UBE2L3 SMURF1 25348397 N/A physical interaction ComPPI
RHPN2 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RTKN SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RHOA SMURF1 14525934 15710384 16472676 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
FLNA SMURF1 25348397 N/A physical interaction ComPPI
SPART SMURF1 25348397 N/A physical interaction ComPPI
KPNB1 SMURF1 25348397 N/A physical interaction ComPPI
PRKAR1A SMURF1 25348397 N/A physical interaction ComPPI
FES SMURF1 25348397 N/A physical interaction ComPPI
UBTF SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PPM1A SMURF1 25348397 N/A physical interaction ComPPI
RASD2 SMURF1 25348397 N/A in vivo ComPPI
PDIA6 SMURF1 25348397 N/A physical interaction ComPPI
UBB SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBC SMURF1 25348397 N/A physical interaction,in vivo ComPPI
RPS27A SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBA52 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBE2N SMURF1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
PDGFRA SMURF1 25348397 N/A physical interaction ComPPI
PICALM SMURF1 25348397 N/A physical interaction ComPPI
PRMT1 SMURF1 25348397 N/A physical interaction ComPPI
BTRC SMURF1 25348397 N/A physical interaction ComPPI
AXIN1 SMURF1 25348397 N/A physical interaction ComPPI
JAK1 SMURF1 25348397 N/A physical interaction ComPPI
YBX1 SMURF1 25348397 N/A physical interaction ComPPI
TLN1 SMURF1 25348397 N/A physical interaction ComPPI
RPS3A SMURF1 25348397 N/A physical interaction ComPPI
XRCC5 SMURF1 25348397 N/A physical interaction ComPPI
HSPA5 SMURF1 25348397 N/A physical interaction ComPPI
MAP3K10 SMURF1 25348397 N/A physical interaction ComPPI
HSPA1A SMURF1 25348397 N/A physical interaction ComPPI
HSPA1B SMURF1 25348397 N/A physical interaction ComPPI
SUB1 SMURF1 25348397 N/A physical interaction ComPPI
ING1 SMURF1 25348397 N/A physical interaction ComPPI
ASH2L SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
HNRNPU SMURF1 25348397 N/A physical interaction ComPPI
XRCC6 SMURF1 25348397 N/A physical interaction ComPPI
EEF1A1 SMURF1 25348397 N/A physical interaction ComPPI
CAPZA1 SMURF1 25348397 N/A physical interaction ComPPI
PRMT5 SMURF1 25348397 N/A physical interaction ComPPI
HNRNPL SMURF1 25348397 N/A physical interaction ComPPI
DCTN1 SMURF1 25348397 N/A physical interaction ComPPI
NEK2 SMURF1 25348397 N/A physical interaction ComPPI
CALCOCO1 SMURF1 25348397 N/A physical interaction ComPPI
DDX5 SMURF1 25348397 N/A physical interaction ComPPI
FSCN1 SMURF1 25348397 N/A physical interaction ComPPI
PDLIM7 SMURF1 25348397 N/A physical interaction ComPPI
SPTAN1 SMURF1 25348397 N/A physical interaction ComPPI
PPP2CA SMURF1 25348397 N/A physical interaction ComPPI
PRKCG SMURF1 25348397 N/A physical interaction ComPPI
PARD6A SMURF1 25348397 N/A physical interaction ComPPI
SQSTM1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
STK38 SMURF1 25348397 N/A physical interaction ComPPI
ITGB1BP1 SMURF1 25348397 N/A physical interaction ComPPI
RABEP1 SMURF1 25348397 N/A physical interaction ComPPI
TNIK SMURF1 25348397 N/A physical interaction ComPPI
RBM10 SMURF1 25348397 N/A physical interaction ComPPI
EPHA1 SMURF1 25348397 N/A physical interaction ComPPI
UBAC1 SMURF1 25348397 N/A physical interaction ComPPI
H2BC21 SMURF1 25348397 N/A physical interaction ComPPI
XPO1 SMURF1 12519765 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
DNAJC7 SMURF1 25348397 N/A in vivo ComPPI
YWHAQ SMURF1 25348397 N/A physical interaction ComPPI
CLASP2 SMURF1 25348397 N/A physical interaction ComPPI
TMPO SMURF1 25348397 N/A physical interaction ComPPI
PSMC5 SMURF1 23032291 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIP10 SMURF1 25348397 N/A physical interaction ComPPI
CLTC SMURF1 25348397 N/A physical interaction ComPPI
RPS6 SMURF1 25348397 N/A physical interaction ComPPI
RPS25 SMURF1 25348397 N/A physical interaction ComPPI
UBQLN2 SMURF1 25348397 N/A physical interaction ComPPI
RAD23A SMURF1 25348397 N/A physical interaction ComPPI
ANKRD13A SMURF1 25348397 N/A physical interaction ComPPI
EPN3 SMURF1 25348397 N/A physical interaction ComPPI
RPS18 SMURF1 25348397 N/A physical interaction ComPPI
RPS13 SMURF1 25348397 N/A physical interaction ComPPI
EPN1 SMURF1 25348397 N/A physical interaction ComPPI
TOM1L2 SMURF1 25348397 N/A physical interaction ComPPI
RIT1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
AP2B1 SMURF1 25348397 N/A in vivo ComPPI
HNRNPA2B1 SMURF1 25348397 N/A physical interaction ComPPI
SRSF1 SMURF1 25348397 N/A physical interaction ComPPI
ZRANB2 SMURF1 25348397 N/A physical interaction ComPPI
HOMER2 SMURF1 25348397 N/A physical interaction ComPPI
NEDD8 SMURF1 25348397 N/A physical interaction ComPPI
DVL2 SMURF1 14525934 19379695 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
SNRPD3 SMURF1 25348397 N/A physical interaction ComPPI
CSNK2A2 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
WDR77 SMURF1 25348397 N/A physical interaction ComPPI
MDM2 SMURF1 25348397 N/A physical interaction ComPPI
EPB41L3 SMURF1 25348397 N/A physical interaction ComPPI
SPTBN1 SMURF1 25348397 N/A physical interaction ComPPI
ACTR1A SMURF1 25348397 N/A physical interaction ComPPI
ODF2 SMURF1 25348397 N/A physical interaction ComPPI
CHEK1 SMURF1 24234451 25249323 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
SYNCRIP SMURF1 25348397 N/A physical interaction ComPPI
TUBA1A SMURF1 25348397 N/A physical interaction ComPPI
VHL SMURF1 25348397 N/A physical interaction ComPPI
PSMC4 SMURF1 25348397 N/A physical interaction ComPPI
MARK2 SMURF1 25348397 N/A physical interaction ComPPI
FKBP3 SMURF1 25348397 N/A physical interaction ComPPI
TCP1 SMURF1 25348397 N/A physical interaction ComPPI
CCT7 SMURF1 25348397 N/A physical interaction ComPPI
ACVR1B SMURF1 25348397 N/A physical interaction ComPPI
CTTN SMURF1 25348397 N/A physical interaction ComPPI
WEE1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
OGT SMURF1 25348397 N/A physical interaction ComPPI
SF3A1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TRIM28 SMURF1 25348397 N/A physical interaction ComPPI
MAP4K5 SMURF1 25348397 N/A physical interaction ComPPI
POLR2A SMURF1 25348397 N/A physical interaction ComPPI
IRAK2 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RASSF1 SMURF1 25348397 N/A physical interaction ComPPI
EFNB1 SMURF1 25348397 N/A physical interaction ComPPI
PRKCI SMURF1 25348397 N/A physical interaction ComPPI
BMPR1B SMURF1 25348397 N/A physical interaction ComPPI
STRAP SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PPP2R2A SMURF1 25348397 N/A physical interaction ComPPI
TNNT1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CTNNB1 SMURF1 25348397 26015066 27898060 N/A physical interaction ComPPI,OmniPath
TUBB4B SMURF1 25348397 N/A physical interaction ComPPI
TNIP2 SMURF1 25348397 N/A physical interaction ComPPI
HSPA9 SMURF1 25348397 N/A physical interaction ComPPI
UBE2K SMURF1 25348397 N/A physical interaction ComPPI
SETD7 SMURF1 25348397 N/A physical interaction ComPPI
TNK2 SMURF1 25348397 N/A physical interaction ComPPI
RIPK2 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMD2 SMURF1 25348397 N/A physical interaction ComPPI
MSN SMURF1 25348397 N/A physical interaction ComPPI
ATXN3 SMURF1 25348397 N/A physical interaction ComPPI
ETV6 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRAF4 SMURF1 19937093 23973329 25348397 27898060 N/A physical interaction ComPPI,OmniPath
LIMS1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FHL1 SMURF1 25348397 N/A physical interaction ComPPI
SSB SMURF1 25348397 N/A physical interaction ComPPI
LRPPRC SMURF1 25348397 N/A physical interaction ComPPI
PSMD4 SMURF1 25348397 N/A physical interaction ComPPI
MYD88 SMURF1 25348397 N/A physical interaction ComPPI
BCLAF1 SMURF1 25348397 N/A physical interaction ComPPI
GRIPAP1 SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ARHGEF9 SMURF1 14525934 18208356 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
PRPS1 SMURF1 25348397 N/A physical interaction ComPPI
UBE2D3 SMURF1 25348397 N/A physical interaction ComPPI
UBA1 SMURF1 24234451 25260751 25348397 ubiquitination reaction ubiquitinase assay ComPPI,IntAct
NFIC SMURF1 25348397 N/A physical interaction ComPPI
AVEN SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RUNX3 SMURF1 25348397 N/A physical interaction,in vivo ComPPI
SMURF1 SMAD6 11278251 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SMURF1 ANAPC5 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 APBB2 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 ARL14 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 ARHGAP15 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 CDC40 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 CDKL1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 CXXC1 25348397 N/A in vivo ComPPI
SMURF1 DUSP13 25348397 N/A in vivo ComPPI
SMURF1 ELP3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 FBXO30 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 FCHO1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 HDGFL3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 ING2 14525934 15761153 20621832 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
SMURF1 INPP5B 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 LHX9 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 LONRF3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 NAA16 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 PAK1IP1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 CDK14 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 PWP1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 RNF141 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 SRSF4 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 SRSF5 25348397 N/A in vivo ComPPI
SMURF1 ECSIT 14525934 15761153 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
SMURF1 STK35 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 STUB1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 TTC17 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 WDR61 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 ZBTB8B 25348397 N/A in vivo ComPPI
SMURF1 PLEKHO1 14525934 15761153 20580715 23032291 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
SMURF1 RRP9 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 UBXN1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 ARHGAP31 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 SASH3 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SMURF1 MAP3K2 14525934 15820682 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
SMURF1 TGFBR1 25348397 N/A physical interaction ComPPI
SMURF1 KLF2 21382345 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct,OmniPath
SMURF1 WFS1 21454619 25348397 27898060 N/A physical interaction ComPPI,OmniPath
SMURF1 ESR1 25348397 N/A physical interaction ComPPI
SMURF1 PSME3 20580715 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
SMURF1 TP53 25348397 N/A physical interaction ComPPI
SMURF1 ACVR1 25348397 N/A physical interaction ComPPI
SMURF1 BMPR1A 25348397 N/A physical interaction ComPPI
SMURF1 CCM2 25348397 N/A physical interaction ComPPI
SMURF1 MAP3K3 25348397 N/A physical interaction ComPPI
SMURF1 NDFIP1 25348397 N/A physical interaction ComPPI
SMURF1 MAVS 25348397 N/A physical interaction ComPPI
SMURF1 APP 25348397 N/A physical interaction ComPPI
SMURF1 ARHGAP32 25348397 N/A physical interaction ComPPI
SMURF1 NUDT5 25348397 N/A physical interaction ComPPI
SMURF1 PPAT 25348397 N/A physical interaction ComPPI
SMURF1 USP9X 25348397 N/A physical interaction ComPPI
SMURF1 RPS11 25348397 N/A physical interaction ComPPI
SMURF1 NUMA1 25348397 N/A physical interaction ComPPI
SMURF1 RPS12 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPA1 25348397 N/A physical interaction ComPPI
SMURF1 RPS17 25348397 N/A physical interaction ComPPI
SMURF1 RPS19 25348397 N/A physical interaction ComPPI
SMURF1 MRPS22 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPA0 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPAB 25348397 N/A physical interaction ComPPI
SMURF1 U2AF1 25348397 N/A physical interaction ComPPI
SMURF1 RPS15A 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPD 25348397 N/A physical interaction ComPPI
SMURF1 RPS10 25348397 N/A physical interaction ComPPI
SMURF1 CPSF6 25348397 N/A physical interaction ComPPI
SMURF1 H1-2 25348397 N/A physical interaction ComPPI
SMURF1 RPS3 25348397 N/A physical interaction ComPPI
SMURF1 RPS8 25348397 N/A physical interaction ComPPI
SMURF1 RPL17 25348397 N/A physical interaction ComPPI
SMURF1 RPL22 25348397 N/A physical interaction ComPPI
SMURF1 RPS4X 25348397 N/A physical interaction ComPPI
SMURF1 RPS20 25348397 N/A physical interaction ComPPI
SMURF1 NCL 25348397 N/A physical interaction ComPPI
SMURF1 MRPS27 25348397 N/A physical interaction ComPPI
SMURF1 FASN 25348397 N/A physical interaction ComPPI
SMURF1 SLC25A3 25348397 N/A physical interaction ComPPI
SMURF1 SF3B2 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPA3 25348397 N/A physical interaction ComPPI
SMURF1 RPS9 25348397 N/A physical interaction ComPPI
SMURF1 RPS16 25348397 N/A physical interaction ComPPI
SMURF1 TIMM50 25348397 N/A physical interaction ComPPI
SMURF1 RPS5 25348397 N/A physical interaction ComPPI
SMURF1 CCT2 25348397 N/A physical interaction ComPPI
SMURF1 SLC25A5 25348397 N/A physical interaction ComPPI
SMURF1 RPL24 25348397 N/A physical interaction ComPPI
SMURF1 CCT4 25348397 N/A physical interaction ComPPI
SMURF1 MAP1B 25348397 N/A physical interaction ComPPI
SMURF1 CCAR1 25348397 N/A physical interaction ComPPI
SMURF1 USP15 25348397 N/A physical interaction ComPPI
SMURF1 CCT8 25348397 N/A physical interaction ComPPI
SMURF1 EEF1A1P5 25348397 N/A physical interaction ComPPI
SMURF1 EEF1G 25348397 N/A physical interaction ComPPI
SMURF1 EIF3A 25348397 N/A physical interaction ComPPI
SMURF1 SNRPD2 25348397 N/A physical interaction ComPPI
SMURF1 HSPD1 25348397 N/A physical interaction ComPPI
SMURF1 CIRBP 25348397 N/A physical interaction ComPPI
SMURF1 TMPO 25348397 N/A physical interaction ComPPI
SMURF1 IVNS1ABP 25348397 N/A physical interaction ComPPI
SMURF1 LTBP1 25348397 N/A physical interaction ComPPI
SMURF1 ANKFY1 25348397 N/A physical interaction ComPPI
SMURF1 SPIN1 25348397 N/A physical interaction ComPPI
SMURF1 KIF11 25348397 N/A physical interaction ComPPI
SMURF1 STK38L 25348397 N/A physical interaction ComPPI
SMURF1 CCT6A 25348397 N/A physical interaction ComPPI
SMURF1 PRPF31 25348397 N/A physical interaction ComPPI
SMURF1 RPL31 25348397 N/A physical interaction ComPPI
SMURF1 EIF4B 25348397 N/A physical interaction ComPPI
SMURF1 CMBL 25348397 N/A physical interaction ComPPI
SMURF1 KCTD5 25348397 N/A physical interaction ComPPI
SMURF1 E2F7 25348397 N/A physical interaction ComPPI
SMURF1 MAT2A 25348397 N/A physical interaction ComPPI
SMURF1 EEF2 25348397 N/A physical interaction ComPPI
SMURF1 YY1AP1 25348397 N/A physical interaction ComPPI
SMURF1 COPRS 25348397 N/A physical interaction ComPPI
SMURF1 PSMA4 25348397 N/A physical interaction ComPPI
SMURF1 HNRNPH1 25348397 N/A physical interaction ComPPI
SMURF1 GOLGA3 25348397 N/A physical interaction ComPPI
SMURF1 RIOK1 25348397 N/A physical interaction ComPPI
SMURF1 CCDC88A 25348397 N/A physical interaction ComPPI
SMURF1 DCTN2 25348397 N/A physical interaction ComPPI
SMURF1 CCDC88C 25348397 N/A physical interaction ComPPI
SMURF1 ACAP2 25348397 N/A physical interaction ComPPI
SMURF1 THRAP3 25348397 N/A physical interaction ComPPI
SMURF1 RPS24 25348397 N/A physical interaction ComPPI
SMURF1 EIF3B 25348397 N/A physical interaction ComPPI
SMURF1 FBXL15 21572392 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,confocal microscopy ComPPI,IntAct
SMURF1 FBXO42 25348397 N/A physical interaction ComPPI
SMURF1 FBXO21 25348397 N/A physical interaction ComPPI
SMURF1 FBXL5 25348397 N/A physical interaction ComPPI
SMURF1 RNF11 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SMURF1 TRIB2 24234451 25311538 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
SMURF1 UBE2M 25348397 N/A physical interaction ComPPI
SMURF1 SENP8 25348397 N/A physical interaction ComPPI
SMURF1 PTCH1 25348397 N/A physical interaction ComPPI
SMURF1 LATS1 25348397 N/A physical interaction ComPPI
SMURF1 LDLRAD4 25348397 N/A physical interaction ComPPI
SMURF1 FBXO3 25348397 N/A physical interaction ComPPI
SMURF1 NR2E1 25348397 N/A physical interaction ComPPI
SMURF1 USP5 25348397 N/A physical interaction ComPPI
SMURF1 ANKRD13D 25348397 N/A physical interaction ComPPI
SMURF1 UBE2V1 24234451 25260751 25348397 ubiquitination reaction physical interaction,ubiquitinase assay ComPPI,IntAct
SMURF1 TOM1 25348397 N/A physical interaction ComPPI
SMURF1 RBCK1 25348397 N/A physical interaction ComPPI
SMURF1 CUEDC1 25348397 N/A physical interaction ComPPI
SMURF1 MINDY3 25348397 N/A physical interaction ComPPI
SMURF1 TAOK3 25348397 N/A physical interaction ComPPI
SMURF1 ILRUN 25348397 N/A physical interaction ComPPI
SMURF1 ANKS4B 25348397 N/A physical interaction ComPPI
SMURF1 UBXN6 25348397 N/A physical interaction ComPPI
SMURF1 UBQLN1 25348397 N/A physical interaction ComPPI
SMURF1 HIP1 25348397 N/A physical interaction ComPPI
SMURF1 UBXN7 25348397 N/A physical interaction ComPPI
SMURF1 ENTR1 25348397 N/A physical interaction ComPPI
SMURF1 ANKRD50 25348397 N/A physical interaction ComPPI
SMURF1 TPM4 25348397 N/A physical interaction ComPPI
SMURF1 KRT36 25348397 N/A physical interaction ComPPI
SMURF1 FAF2 25348397 N/A physical interaction ComPPI
SMURF1 ELOF1 25348397 N/A physical interaction ComPPI
SMURF1 RIOK3 25348397 N/A physical interaction ComPPI
SMURF1 SCYL1 25348397 N/A physical interaction ComPPI
SMURF1 RNF114 25348397 N/A physical interaction ComPPI
SMURF1 MAP3K9 25348397 N/A physical interaction ComPPI
SMURF1 IMPACT 25348397 N/A physical interaction ComPPI
SMURF1 ANXA6 25348397 N/A physical interaction ComPPI
SMURF1 SLAIN2 25348397 N/A physical interaction ComPPI
SMURF1 OTUD6B 25348397 N/A physical interaction ComPPI
SMURF1 PRR16 25348397 N/A physical interaction ComPPI
SMURF1 ASCC2 25348397 N/A physical interaction ComPPI
SMURF1 FGF12 25348397 N/A physical interaction ComPPI
SMURF1 FGR 25348397 N/A physical interaction ComPPI
SMURF1 C9ORF78 25348397 N/A physical interaction ComPPI
SMURF1 CCDC69 25348397 N/A physical interaction ComPPI
SMURF1 TAB1 25348397 N/A physical interaction ComPPI
SMURF1 GRK3 25348397 N/A physical interaction ComPPI
SMURF1 STK31 25348397 N/A physical interaction ComPPI
SMURF1 DDX54 25348397 N/A physical interaction ComPPI
SMURF1 TBK1 25348397 N/A physical interaction ComPPI
HNRNPF SMURF1 25348397 N/A physical interaction ComPPI
ARL4D SMURF1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RPL23 SMURF1 25348397 N/A physical interaction ComPPI
EEF1D SMURF1 25348397 N/A physical interaction ComPPI
EEF1B2 SMURF1 25348397 N/A physical interaction ComPPI
ZFAND5 SMURF1 25348397 N/A physical interaction ComPPI
ADRM1 SMURF1 25348397 N/A physical interaction ComPPI
RPS14 SMURF1 25348397 N/A physical interaction ComPPI
MRPS23 SMURF1 25348397 N/A physical interaction ComPPI
NDFIP2 SMURF1 14525934 15252135 N/A experimental interaction detection HPRD
DUSP13 SMURF1 14525934 15761153 N/A experimental interaction detection HPRD
SMURF1 TGFBR2 11278251 22298955 27898060 inhibition N/A OmniPath
KAT2A SMURF1 12408818 27898060 inhibition N/A OmniPath
SMURF1 SMAD1 14701756 14711801 15221015 15231748 15761153 16611643 17289590 17510966 17676934 19914168 19917253 21685363 21708152 22152476 22298955 22670624 24828823 27898060 inhibition N/A OmniPath
SMURF1 SMAD5 11278251 12857866 14711801 15221015 15231748 16516194 17676934 18641638 19914168 20484049 22298955 22670624 27898060 inhibition N/A OmniPath
SMURF1 SMAD2 10458166 15221015 15231748 20207742 27898060 stimulant N/A OmniPath
SMURF1 SMAD4 15817471 23973329 27898060 inhibition N/A OmniPath
SMURF1 TGFBR1 11278251 12519765 12857866 14657019 17317136 27898060 inhibition,stimulant N/A OmniPath
SMURF1 SMAD3 10458166 15221015 1522102 15231748 15761153 27898060 stimulant N/A OmniPath
SMURF1 RUNX2 12738770 14701828 16299379 27898060 inhibition,stimulant N/A OmniPath
SMURF1 SMAD9 22298955 27898060 inhibition N/A OmniPath
SMURF1 BMPR1A 17317136 22298955 27898060 inhibition N/A OmniPath
SMURF1 DAB2IP 27858941 27898060 inhibition N/A OmniPath
SMAD7 SMURF1 11278251 12151385 12408818 12519765 14722617 15221015 16720724 19352540 20937913 21791611 22152476 22773947 22921829 23959799 24700460 27898060 stimulant N/A OmniPath
SMURF1 SMAD7 11278251 12151385 12408818 12519765 14722617 15221015 16720724 19352540 20937913 21791611 22152476 22773947 22921829 23959799 24700460 27898060 inhibition,stimulant N/A OmniPath
SMURF1 SMAD6 11278251 15221015 17676934 21897371 22298955 27898060 inhibition,stimulant N/A OmniPath
SMURF1 BMPR2 17317136 22298955 27898060 inhibition N/A OmniPath
PARD6A SMURF1 15761148 19114990 2126246 21262463 27898060 stimulant N/A OmniPath

Visualization










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