Gene Information gene info

GENE:FST

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FST
FullNmae follistatin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3971
EnsembleID ENSG00000134363
Uniprot P19883

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FST apoptosis 34001106 FST inhibited the apoptosis of mesenchymal cells by targeting BMP7. retulator signature

Go Annotation:

GeneSymbol Go id
FST GO:0000122,GO:0001501,GO:0002244,GO:0005515,GO:0005576,GO:0005615,GO:0005634,GO:0005737,GO:0007275,GO:0007276,GO:0007389,GO:0008585,GO:0014070,GO:0030154,GO:0030509,GO:0030510,GO:0030857,GO:0031069,GO:0032926,GO:0032926,GO:0032926,GO:0036305,GO:0038102,GO:0042475,GO:0043395,GO:0043616,GO:0048185,GO:0048185,GO:0051798

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FST hsa:10468 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FST GLI2 18319260 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FST 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 FST 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 FST 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FST 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
RELA FST 18226221 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 FST 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 FST 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FST 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA1 FST 22685544 trascriptional regulation,stimulation inferred by curator TFlink
CTNNB1 FST 24667650 trascriptional regulation,stimulation inferred by curator TFlink
GLI2 FST 18319260 trascriptional regulation,stimulation inferred by curator TFlink
SMAD3 FST 24330518 trascriptional regulation,stimulation inferred by curator TFlink
TCF7L2 FST 24667650 trascriptional regulation,stimulation inferred by curator TFlink
TCF4 FST 24667650 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FF522 FST 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 FST 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HOXA1 FST 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CATSPER1 FST 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TK1 FST 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ADAM12 FST 25348397 N/A far western blotting ComPPI
ZNF587 FST 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXN FST 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BMPR2 FST 25348397 N/A physical interaction ComPPI
ANG FST 17991437 24234451 25348397 27898060 colocalization,physical association two hybrid,fluorescent resonance energy transfer,pull down,confocal microscopy ComPPI,IntAct,OmniPath
BMPR1A FST 25348397 N/A physical interaction ComPPI
INHBA FST 14525934 25348397 7887917 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FST BMP5 11580864 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FST INHBE 12242034 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
FST MEST 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FST C8ORF33 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FST ADAM8 15574124 24234451 25348397 N/A far western blotting ComPPI,IntAct
FST FSTL1 20860622 24234451 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
FST DIP2A 20860622 24234451 25348397 physical association surface plasmon resonance,competition binding,surface plasmon resonance array ComPPI,IntAct
FST BEX2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
INHA FST 14525934 2036994 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FN1 FST 14525934 16336961 N/A experimental interaction detection HPRD
FST KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
NPM1 FST 24234451 30021884 physical association cross-linking study IntAct
CREB1 FST 17482756 27898060 stimulant N/A OmniPath
FST INHBA 22037168 27898060 7887917 inhibition N/A OmniPath

Visualization