Gene Information gene info

GENE:PXN

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PXN
FullNmae paxillin
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9718
EnsembleID ENSG00000089159
Uniprot P49023

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PXN apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PXN GO:0001725,GO:0005515,GO:0005829,GO:0005829,GO:0005875,GO:0005886,GO:0005886,GO:0005911,GO:0005925,GO:0005925,GO:0005925,GO:0005938,GO:0007155,GO:0007165,GO:0007172,GO:0007179,GO:0007179,GO:0008013,GO:0016477,GO:0017166,GO:0019903,GO:0030027,GO:0034446,GO:0034614,GO:0038191,GO:0043542,GO:0043542,GO:0046872,GO:0051496,GO:0060396

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PXN hsa:5829 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
PXN hsa:5829 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
PXN hsa:5829 path:hsa04510 Focal adhesion - Homo sapiens (human)
PXN hsa:5829 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
PXN hsa:5829 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
PXN hsa:5829 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
PXN hsa:5829 path:hsa05131 Shigellosis - Homo sapiens (human)
PXN hsa:5829 path:hsa05135 Yersinia infection - Homo sapiens (human)
PXN hsa:5829 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
PXN hsa:5829 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
PXN hsa:5829 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
PXN hsa:5829 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)
PXN hsa:5829 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PXN TUBGCP2 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 26192618 29021139 interaction type N/A ACSN
PXN TUBGCP3 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 26192618 29021139 interaction type N/A ACSN
PXN TUBGCP4 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 26192618 29021139 interaction type N/A ACSN
PXN TUBGCP5 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 26192618 29021139 interaction type N/A ACSN
PXN TUBGCP6 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 26192618 29021139 interaction type N/A ACSN
PXN BCAR1 12473693 14749719 15094799 15308668 15688067 16000375 18287025 18829532 18835194 22043013 26192618 29021139 9819392 interaction type N/A ACSN
PXN DOCK1 11146654 12432077 14697347 15308668 16000375 18287025 22043013 26192618 29021139 9808620 association N/A ACSN
ICAM1 PXN 10591186 11592085 12413632 12616499 14662834 15356110 1673988 19454690 19965656 20231889 2150484 23364881 23886063 24343663 24440149 25384214 26192618 7512027 9712030 9738502 interaction type N/A ACSN
TLN1 PXN 10591186 11592085 12413632 12616499 14662834 15356110 1673988 19454690 19965656 20231889 2150484 23364881 23886063 24343663 24440149 25384214 26192618 7512027 9712030 9738502 interaction type N/A ACSN
CD247 PXN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 PXN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
TRIP10 PXN 10467124 10511705 10713100 11395419 11520460 12177428 14707117 15001467 15541654 16293614 16606694 17785506 19741094 21178402 23212475 26192618 8625410 interaction type N/A ACSN
CDC42 PXN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 26192618 27248291 7761442 9831565 interaction type N/A ACSN
IQGAP1 PXN 15263019 22573807 26192618 interaction type N/A ACSN
VAV1 PXN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26192618 26552706 8189062 8226994 9438848 interaction type N/A ACSN
DIAPH1 PXN 15866170 16292343 17306570 17575049 26192618 interaction type N/A ACSN
PTP4A3 PXN 17409395 23691193 24376839 26192618 27588115 interaction type N/A ACSN
CRK PXN 15308668 16000375 26192618 association N/A ACSN
PTK2 PXN 11113628 23180781 physical association anti tag coimmunoprecipitation InnateDB
CD36 PXN 20037584 23180781 physical association anti tag coimmunoprecipitation InnateDB
PXN SELE 23180781 8609175 physical association anti tag coimmunoprecipitation InnateDB
CEACAM1 PXN 11035932 23180781 physical association anti tag coimmunoprecipitation InnateDB
LCP1 PXN 21525390 23180781 physical association anti tag coimmunoprecipitation InnateDB
PXN IL32 22203669 23180781 physical association enzyme linked immunosorbent assay InnateDB
FGR PXN 23109003 9636140 chemical activation reaction N/A SignaLink
HCK PXN 23109003 9636140 chemical activation reaction N/A SignaLink
LYN PXN 23109003 9636140 chemical activation reaction N/A SignaLink
SRC PXN 23109003 9636140 chemical activation reaction N/A SignaLink
MAPK14 PXN 22865050 23109003 chemical activation reaction N/A SignaLink
PXN NFATC2 22865050 23109003 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
PXN PDPK1 20005715 interaction type N/A PSP,SignaLink
PXN ABL1 20005715 interaction type N/A PSP,SignaLink
PXN ITGB3 20005715 interaction type N/A PSP
PXN ITGB1 20005715 interaction type N/A PSP
PXN LCK 20005715 interaction type N/A PSP,SignaLink
PXN FYN 20005715 interaction type N/A PSP,SignaLink
PXN IGF1R 20005715 interaction type N/A PSP
PXN PTPRC 20005715 interaction type N/A PSP,SignaLink
PXN AR 20005715 interaction type N/A PSP,SignaLink
PXN BCR 20005715 21071413 8641358 interaction type N/A PSP,SignaLink
PXN SRC 20005715 interaction type N/A PSP
PXN ITGA4 20005715 interaction type N/A PSP
PXN CBL 20005715 interaction type N/A PSP
PXN ITGA6 20005715 interaction type N/A PSP
PXN PTPRG 20005715 interaction type N/A PSP
PXN MAPK3 20005715 interaction type N/A PSP,SignaLink
PXN MAPK1 20005715 interaction type N/A PSP,SignaLink
PXN CSK 20005715 interaction type N/A PSP
PXN MATK 20005715 interaction type N/A PSP
PXN SYK 20005715 interaction type N/A PSP
PXN MAPK8 20005715 interaction type N/A PSP,SignaLink
PXN CRKL 20005715 interaction type N/A PSP
PXN GSK3A 20005715 interaction type N/A PSP,SignaLink
PXN GSK3B 20005715 interaction type N/A PSP,SignaLink
PXN LIMK1 20005715 interaction type N/A PSP
PXN PTEN 20005715 interaction type N/A PSP
PXN PPP2CA 20005715 interaction type N/A PSP
PXN PTK2 20005715 interaction type N/A PSP
PXN PTPN11 20005715 interaction type N/A PSP,SignaLink
PXN PTPRJ 20005715 interaction type N/A PSP
PXN ARHGAP5 20005715 interaction type N/A PSP
PXN PAK1 20005715 interaction type N/A PSP,SignaLink
PXN ILK 20005715 interaction type N/A PSP
PXN ITGA9 20005715 interaction type N/A PSP
PXN PTK2B 11036077 20005715 21071413 9099734 9422762 interaction type N/A PSP,SignaLink
PXN PTPRK 20005715 interaction type N/A PSP
PXN CBL 20005715 21071413 22203672 8641358 N/A N/A SignaLink
PXN CRKL 11463817 20005715 21071413 7493940 N/A N/A SignaLink
PXN IGF1R 10082579 20005715 21071413 N/A N/A SignaLink
PXN PTEN 11857088 20005715 21071413 N/A N/A SignaLink
PXN SRC 10085298 20005715 21071413 N/A N/A SignaLink
PXN CSK 20005715 20005715 21071413 7529872 N/A N/A SignaLink
PXN MATK 10080957 20005715 20005715 21071413 N/A N/A SignaLink
PXN PPP2CA 10675325 20005715 20005715 21071413 N/A N/A SignaLink
PXN PTK2 10753828 11919182 11919182 20005715 20005715 21071413 9422762 9442086 N/A N/A SignaLink
PXN SYK 20005715 20005715 21071413 9590268 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR PXN 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PXN 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PXN 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PXN 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PXN 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PXN 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PXN 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PXN 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PXN 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E3523 PXN 23275153 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001E3523 PXN 23275153 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000237AF9 PXN 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000170CF4 PXN 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001AFC71 PXN 25416803 26693054 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000330617 PXN 25416803 26473412 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00004F4657 PXN 25416803 25973017 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003CC709 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023BE29 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000939AF PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237E04 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000393C7 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000458AD2 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000057FDB8 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001ADE63 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AA845 PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000025EABA PXN 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC PXN 22135298 phosphorylation N/A PhosphoSite
ABL1 PXN 22135298 phosphorylation N/A PhosphoSite
MAPK14 PXN 22135298 phosphorylation N/A PhosphoSite
CDK5 PXN 22135298 phosphorylation N/A PhosphoSite
PAK1 PXN 22135298 phosphorylation N/A PhosphoSite
MAPK8 PXN 22135298 phosphorylation N/A PhosphoSite
PAK2 PXN 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
YES1 PXN 25348397 N/A two hybrid ComPPI
DPY30 PXN 25348397 N/A two hybrid ComPPI
SEC23B PXN 25348397 N/A physical interaction ComPPI
RABGGTB PXN 25348397 N/A physical interaction ComPPI
PTPRH PXN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
CRK PXN 12799422 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
EXOSC8 PXN 25348397 N/A physical interaction ComPPI
RNF5 PXN 12861019 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
PAK1 PXN 25348397 N/A in vitro ComPPI
ARHGAP5 PXN 25348397 N/A physical interaction ComPPI
NF2 PXN 25348397 N/A physical interaction,in vitro ComPPI
CBL PXN 25348397 N/A physical interaction ComPPI
MAPK1 PXN 24234451 25241761 25348397 physical association physical interaction,in vitro,proximity ligation assay ComPPI,IntAct
SYK PXN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PTK2B PXN 25348397 N/A physical interaction,in vitro ComPPI
ZYX PXN 25348397 N/A physical interaction ComPPI
CD36 PXN 20037584 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
MAPK8 PXN 23397142 24234451 25348397 physical association in vitro,in vivo,proximity ligation assay ComPPI,IntAct
PIK3R1 PXN 23397142 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PTPN11 PXN 14665621 23397142 24234451 25348397 association,physical association anti bait coimmunoprecipitation,in vitro,in vivo,proximity ligation assay ComPPI,IntAct
SRC PXN 14665621 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,in vitro ComPPI,IntAct
MATK PXN 25348397 N/A physical interaction,in vitro ComPPI
PTPRO PXN 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
CRKL PXN 24234451 25348397 7493940 association pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
LCK PXN 25348397 N/A physical interaction,in vivo ComPPI
NCK1 PXN 25348397 N/A physical interaction,in vitro ComPPI
DSTN PXN 25348397 N/A physical interaction ComPPI
CASP3 PXN 25348397 N/A in vitro ComPPI
MAPK3 PXN 25348397 N/A in vitro ComPPI
GRB2 PXN 25348397 N/A physical interaction ComPPI
NEDD9 PXN 25348397 N/A physical interaction,in vivo ComPPI
AR PXN 25348397 N/A in vitro ComPPI
BLK PXN 25348397 N/A two hybrid ComPPI
ITGB1 PXN 10604475 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
SORBS1 PXN 25348397 N/A in vitro,in vivo ComPPI
ITGAV PXN 25348397 N/A physical interaction ComPPI
ITGA9 PXN 25348397 N/A in vitro,in vivo ComPPI
GSK3B PXN 25348397 N/A in vivo ComPPI
TUBG1 PXN 25348397 N/A physical interaction,in vitro,in vivo ComPPI
TUBA1B PXN 25348397 N/A two hybrid,in vitro,in vivo ComPPI
GAB1 PXN 14665621 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
PICALM PXN 25348397 N/A physical interaction ComPPI
GIT1 PXN 16628223 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
APC PXN 20224554 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDH1 PXN 25348397 N/A physical interaction ComPPI
PKD1 PXN 25348397 N/A in vitro,in vivo ComPPI
ITGB3 PXN 25348397 N/A physical interaction ComPPI
TLN1 PXN 25348397 N/A physical interaction,in vivo ComPPI
ILK PXN 17553790 24234451 25348397 25852190 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
PDPK1 PXN 25348397 N/A in vitro ComPPI
PARVA PXN 11134073 24234451 25348397 physical association anti bait coimmunoprecipitation,classical fluorescence spectroscopy,nuclear magnetic resonance,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,IntAct
PXN ITGA4 10604475 21173240 24234451 25348397 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
PXN VCL 20308429 24234451 25348397 colocalization physical interaction,fluorescence microscopy,in vitro,in vivo ComPPI,IntAct
PXN PAK3 25348397 N/A in vitro ComPPI
PXN REPS2 25348397 N/A in vitro,in vivo ComPPI
PXN PTPN12 19167335 24234451 25348397 dephosphorylation reaction two hybrid,physical interaction,phosphatase assay,in vitro,in vivo ComPPI,IntAct
PXN CEACAM1 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PXN LIMK1 25348397 N/A in vivo ComPPI
PXN PPP2R5C 25348397 N/A in vivo ComPPI
PXN PTEN 23397142 24234451 25348397 physical association physical interaction,in vivo,proximity ligation assay ComPPI,IntAct
PXN TRIP6 25348397 N/A physical interaction,in vivo ComPPI
PXN ASAP2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
PXN PABPC1 25348397 N/A physical interaction,in vivo ComPPI
PXN ARHGEF7 25348397 N/A in vitro ComPPI
PXN TUBA8 25348397 N/A two hybrid,in vivo ComPPI
PXN TUBG2 25348397 N/A in vitro,in vivo ComPPI
PXN ASAP1 16636290 24234451 25348397 physical association pull down,physical interaction,in vitro ComPPI,IntAct
PXN SDC4 25348397 N/A in vitro ComPPI
PXN PPP2CA 25348397 N/A physical interaction,in vivo ComPPI
PXN GIT2 16628223 22728435 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
PXN CLTC 25348397 N/A in vitro ComPPI
PXN EPHB1 25348397 N/A in vivo ComPPI
PXN GSK3A 25348397 N/A in vivo ComPPI
PXN CSK 14665621 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
PXN BCL2 10417825 25348397 27898060 N/A in vitro ComPPI,OmniPath
PXN SELE 25348397 N/A physical interaction,in vitro ComPPI
PXN FYN 25348397 N/A physical interaction,in vivo ComPPI
PXN GSN 25348397 N/A physical interaction,in vivo ComPPI
PXN RASA1 25348397 N/A physical interaction,in vivo ComPPI
PXN ITGA6 25348397 N/A in vivo ComPPI
PXN BCAR1 25348397 N/A physical interaction ComPPI
PXN RAB8B 25348397 N/A physical interaction ComPPI
PXN PTK2 21034468 21741599 22270917 24234451 25348397 7561682 9756887 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,far western blotting,pull down,physical interaction,fluorescence microscopy,confocal microscopy ComPPI,IntAct
PXN TGFB1I1 25348397 N/A physical interaction ComPPI
PXN PKLR 25348397 N/A physical interaction ComPPI
PXN CEACAM5 25348397 N/A physical interaction ComPPI
PXN BCR 25348397 N/A physical interaction ComPPI
PXN CTTN 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PXN IGBP1 25348397 N/A physical interaction ComPPI
PXN NUDCD2 25348397 N/A physical interaction ComPPI
PXN FN1 19738201 21985969 24234451 25348397 colocalization,association cross-linking study,physical interaction,fluorescence microscopy ComPPI,IntAct
PXN XPO1 25348397 N/A physical interaction ComPPI
PXN AHCY 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PXN DGUOK 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PXN GART 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PXN POLR1D 25348397 N/A physical interaction ComPPI
PXN POLR1D 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PXN CREB3L2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PXN NAA10 25348397 N/A physical interaction ComPPI
PXN CHMP5 25348397 N/A physical interaction ComPPI
PXN SEC24D 25348397 N/A physical interaction ComPPI
PXN ADAM17 25348397 N/A physical interaction ComPPI
PXN ADAM10 25348397 N/A physical interaction ComPPI
PXN SHMT2 25348397 N/A physical interaction ComPPI
PXN MOV10 25348397 N/A physical interaction ComPPI
PXN NXF1 25348397 N/A physical interaction ComPPI
PXN ALK 25348397 N/A physical interaction ComPPI
PXN HDAC6 25070956 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PXN LIMS1 25348397 N/A physical interaction ComPPI
PXN TRIM15 25015296 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PXN CAP1 25348397 N/A physical interaction ComPPI
PXN ASNS 25348397 N/A physical interaction ComPPI
PXN GALE 25348397 N/A physical interaction ComPPI
PXN RHOU 25348397 N/A physical interaction ComPPI
PXN PAK4 25348397 N/A physical interaction ComPPI
PXN WHRN 24234451 25348397 physical association two hybrid,physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PXN ARF1 25348397 N/A physical interaction ComPPI
PXN NDEL1 19492042 24234451 25348397 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PXN PTPRT 25348397 N/A pull down,physical interaction ComPPI
PXN EGFR 15657067 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PXN PTPRC 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN PTPRK 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN PTPRG 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN PTPRZ1 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN PTPRB 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN PTPRJ 19167335 24234451 25348397 dephosphorylation reaction phosphatase assay ComPPI,IntAct
PXN ACO1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
PXN VCAM1 19738201 24234451 25348397 association cross-linking study ComPPI,IntAct
PXN CTNNB1 22728435 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
PXN LMO1 25348397 N/A two hybrid ComPPI
IQGAP1 PXN 25348397 N/A physical interaction ComPPI
IGF1R PXN 25348397 N/A physical interaction ComPPI
TSL PXN 25348397 N/A anti tag coimmunoprecipitation ComPPI
RNF-5 PXN 12861019 24234451 physical association anti bait coimmunoprecipitation,pull down IntAct
CDK5 PXN 18042622 27898060 N/A N/A OmniPath
SRC PXN 10823820 11695992 11774284 14636584 15107421 15817476 27898060 7534286 stimulant N/A OmniPath
FYN PXN 10804218 15572663 15870699 15944157 17046825 17148760 17574549 18676874 21399647 21423176 21898535 27898060 7493940 stimulant N/A OmniPath
CASP3 PXN 11447317 11511102 11825902 27898060 inhibition N/A OmniPath
PTK2 PXN 10330411 10455189 10545505 10753828 10764815 10980697 11113628 11134073 11304546 11337490 11514617 11919182 12408869 14527389 17389395 18669648 18707149 20068231 20489202 21034468 21741599 22270917 27898060 7537852 7561682 7615549 8922390 9054445 9230116 9422762 9442086 9658172 9756887 stimulant N/A OmniPath
MAPK3 PXN 11784715 12837288 27898060 N/A N/A OmniPath
ABL1 PXN 11695992 20841568 27898060 9603926 stimulant N/A OmniPath
MAPK1 PXN 14636584 18042622 25241761 27898060 stimulant N/A OmniPath
PAK1 PXN 10330411 11096073 16717130 17440071 23317503 27898060 stimulant N/A OmniPath
PTPN11 PXN 10082579 10655584 14665621 23397142 27898060 8986614 inhibition,stimulant N/A OmniPath
PPP2CA PXN 10675325 27898060 inhibition N/A OmniPath
MAPK8 PXN 12853963 20068231 23397142 27898060 stimulant N/A OmniPath
SELE PXN 27898060 8609175 N/A N/A OmniPath
CEACAM1 PXN 11035932 27898060 N/A N/A OmniPath
CD36 PXN 20037584 27898060 N/A N/A OmniPath
CSK PXN 11695992 14665621 17389395 18707149 27898060 7529872 9890993 stimulant N/A OmniPath
PTK6 PXN 11774284 12837288 15572663 15592455 15951569 16094384 16212419 17081983 17389395 18083107 19534553 27898060 stimulant N/A OmniPath
IL32 PXN 22203669 27898060 N/A N/A OmniPath
PXN ILK 11304546 11694518 16936772 25852190 26496610 27898060 stimulant N/A OmniPath
PTPRR PXN 20133777 27898060 inhibition N/A OmniPath
PPP2CB PXN 10675325 27898060 N/A N/A OmniPath
PAK4 PXN 16717130 18986306 20406887 27898060 N/A N/A OmniPath
PTPRT PXN 20133777 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B15F1 PXN 27087310 direct interaction,inhibition N/A NPInter

Visualization