Gene Information gene info

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GENE：THBS4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol THBS4
FullNmae thrombospondin 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11788
EnsembleID ENSG00000113296
Uniprot P35443

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
THBS4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
THBS4 GO:0001938,GO:0005178,GO:0005509,GO:0005515,GO:0005576,GO:0005604,GO:0005615,GO:0005783,GO:0006986,GO:0007165,GO:0008083,GO:0008201,GO:0016525,GO:0016529,GO:0034103,GO:0034976,GO:0034976,GO:0048266,GO:0048771,GO:0050731,GO:0051451,GO:0051781,GO:0062023,GO:0062023,GO:0070062,GO:0071603,GO:0090023

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
THBS4 hsa:7060 path:hsa04145 Phagosome - Homo sapiens (human)
THBS4 hsa:7060 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
THBS4 hsa:7060 path:hsa04510 Focal adhesion - Homo sapiens (human)
THBS4 hsa:7060 path:hsa04512 ECM-receptor interaction - Homo sapiens (human)
THBS4 hsa:7060 path:hsa05144 Malaria - Homo sapiens (human)
THBS4 hsa:7060 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 THBS4 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC THBS4 12747840 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 THBS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF THBS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 THBS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS THBS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001E0AEA THBS4 25416803 28177895 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
RAD21 THBS4 25348397 N/A physical interaction ComPPI
SLC25A6 THBS4 25348397 N/A physical interaction ComPPI
BBS2 THBS4 25348397 N/A physical interaction ComPPI
ARHGEF1 THBS4 25348397 N/A physical interaction ComPPI
PKN2 THBS4 25348397 N/A physical interaction ComPPI
PLD2 THBS4 25348397 N/A physical interaction ComPPI
THBS1 THBS4 25348397 N/A physical interaction ComPPI
APBB1 THBS4 25348397 N/A physical interaction ComPPI
DNAJA3 THBS4 25348397 N/A physical interaction ComPPI
TUBA4A THBS4 25348397 N/A physical interaction ComPPI
TUBA1A THBS4 25348397 N/A physical interaction ComPPI
CCT7 THBS4 25348397 N/A physical interaction ComPPI
MAP3K7 THBS4 25348397 N/A physical interaction ComPPI
TRO THBS4 25348397 N/A physical interaction ComPPI
RIC8B THBS4 25348397 N/A physical interaction ComPPI
DIP2A THBS4 25348397 N/A physical interaction ComPPI
PEX1 THBS4 25348397 N/A physical interaction ComPPI
PEX6 THBS4 25348397 N/A physical interaction ComPPI
RPL23 THBS4 25348397 N/A physical interaction ComPPI
RAD51C THBS4 25348397 N/A physical interaction ComPPI
ASCC3 THBS4 25348397 N/A physical interaction ComPPI
RFC1 THBS4 25348397 N/A physical interaction ComPPI
TOP2A THBS4 25348397 N/A physical interaction ComPPI
HSPD1 THBS4 25348397 N/A physical interaction ComPPI
PC THBS4 25348397 N/A physical interaction ComPPI
TUBB3 THBS4 25348397 N/A physical interaction ComPPI
CCT2 THBS4 25348397 N/A physical interaction ComPPI
NOL11 THBS4 25348397 N/A physical interaction ComPPI
FANCB THBS4 25348397 N/A physical interaction ComPPI
NSUN2 THBS4 25348397 N/A physical interaction ComPPI
PIK3C2A THBS4 25348397 N/A physical interaction ComPPI
APP THBS4 25348397 N/A physical interaction ComPPI
RIPK4 THBS4 25348397 N/A physical interaction ComPPI
THBS4 SMG8 25348397 N/A physical interaction ComPPI
THBS4 NDUFA3 25348397 N/A physical interaction ComPPI
THBS4 LRWD1 25348397 N/A physical interaction ComPPI
THBS4 MTPAP 25348397 N/A physical interaction ComPPI
THBS4 UTP4 25348397 N/A physical interaction ComPPI
THBS4 BBS7 25348397 N/A physical interaction ComPPI
THBS4 RTEL1 25348397 N/A physical interaction ComPPI
THBS4 CORO7 25348397 N/A physical interaction ComPPI
THBS4 HASPIN 25348397 N/A physical interaction ComPPI
BLVRA THBS4 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00008BF0A9 THBS4 27087310 direct interaction,inhibition N/A NPInter

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