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GENE：TNFRSF10C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNFRSF10C
FullNmae TNF receptor superfamily member 10c
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11906
EnsembleID ENSG00000173535
Uniprot O14798

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNFRSF10C apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TNFRSF10C apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
TNFRSF10C GO:0004888,GO:0005515,GO:0005886,GO:0005886,GO:0009986,GO:0036462,GO:0043065,GO:0045569,GO:0098552

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TNFRSF10C hsa:8794 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
TNFRSF10C hsa:8794 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TNFRSF10C RAP1A 15207703 23180781 physical association antibody array InnateDB

Source Target Pmid Interactiontype Methods Database
ESR2 TNFRSF10C 20034404 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 TNFRSF10C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TNFRSF10C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TNFSF10 TNFRSF10C 25361965 interaction type N/A PTMCode2
TNFRSF10C TNFSF10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SGTA TNFRSF10C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNA TNFRSF10C 25348397 N/A physical interaction ComPPI
SLC25A6 TNFRSF10C 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DNAJC1 TNFRSF10C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APOA1 TNFRSF10C 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAP1A TNFRSF10C 14525934 15207703 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SRPK1 TNFRSF10C 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
ZHX1 TNFRSF10C 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KCNJ6 TNFRSF10C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CD79A TNFRSF10C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRPK2 TNFRSF10C 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
LRSAM1 TNFRSF10C 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TNFSF10 TNFRSF10C 14525934 20103630 24234451 25348397 9314565 9325248 9613612 N/A experimental interaction detection,surface plasmon resonance,in vitro,in vivo,surface plasmon resonance array ComPPI,HPRD,IntAct
TNFRSF10C SLC27A6 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
TNFRSF10C RFLNB 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TNFRSF10C A1BG 25348397 N/A coimmunoprecipitation,physical interaction ComPPI
TNFRSF10C MRPS18B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C MGST1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C TMEM45B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C ERGIC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C SYAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C CREB3L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C KCNK5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C GPR37L1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C COQ9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C PDZK1IP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C ARL13B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C ASZ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C SLC30A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C CYB5R3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C TMEM80 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFRSF10C STOM 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TP53 TNFRSF10C 10435597 10933923 14623878 18431400 27898060 stimulant N/A OmniPath
TNFRSF10C TNFSF10 20103630 27898060 9082980 9314565 9325248 9613612 inhibition N/A OmniPath
TNFSF10 TNFRSF10C 20103630 27898060 9082980 9314565 9325248 9613612 inhibition,stimulant N/A OmniPath
RAP1A TNFRSF10C 15207703 27898060 N/A N/A OmniPath

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