Gene Information gene info

  1. Home

GENE：PLA2G4B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLA2G4B
FullNmae phospholipase A2 group IVB
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9036
EnsembleID ENSG00000243708
Uniprot P0C869

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLA2G4B apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLA2G4B GO:0004622,GO:0004623,GO:0005509,GO:0005509,GO:0005544,GO:0005544,GO:0005576,GO:0005743,GO:0005829,GO:0005829,GO:0005829,GO:0006954,GO:0007567,GO:0008970,GO:0019369,GO:0019722,GO:0031901,GO:0036148,GO:0046475,GO:0046475,GO:0047498,GO:0047498,GO:0102545

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLA2G4B hsa:100137049 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa00591 Linoleic acid metabolism - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04217 Necroptosis - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04611 Platelet activation - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04726 Serotonergic synapse - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04730 Long-term depression - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04913 Ovarian steroidogenesis - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
PLA2G4B hsa:100137049 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CREB1 PLA2G4B 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 PLA2G4B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MITF PLA2G4B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000254A6 PLA2G4B 18991333 rna interference,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay miRSponge
URS00000254A6 PLA2G4B 18991333 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CASP3 PLA2G4B 25348397 N/A physical interaction ComPPI
SMARCD1 PLA2G4B 25348397 N/A physical interaction ComPPI
CASP1 PLA2G4B 25348397 N/A physical interaction ComPPI
CASP7 PLA2G4B 25348397 N/A physical interaction ComPPI
CASP8 PLA2G4B 25348397 N/A physical interaction ComPPI
ZDHHC17 PLA2G4B 25348397 N/A physical interaction ComPPI
SHBG PLA2G4B 14525934 15862967 25348397 N/A two hybrid,two hybrid ComPPI,HPRD

Visualization










  Return