Gene Information gene info

  1. Home

GENE：TPX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TPX2
FullNmae TPX2 microtubule nucleation factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1249
EnsembleID ENSG00000088325
Uniprot Q9ULW0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TPX2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TPX2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TPX2 GO:0000278,GO:0000922,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005819,GO:0005829,GO:0005874,GO:0006915,GO:0007020,GO:0007026,GO:0015630,GO:0019901,GO:0032147,GO:0043203,GO:0045171,GO:0051301,GO:0060236,GO:0061676,GO:0072686,GO:0090307

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SIAH2 TPX2 17716627 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
AR TPX2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 TPX2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 TPX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR TPX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 TPX2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
AURKA TPX2 22135298 phosphorylation N/A PhosphoSite
CDK1 TPX2 22135298 phosphorylation N/A PhosphoSite
CDK2 TPX2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GOLGA2 TPX2 25348397 N/A physical interaction ComPPI
CDC5L TPX2 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTM3 TPX2 25348397 N/A physical interaction ComPPI
CDK6 TPX2 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
KPNA1 TPX2 25348397 N/A physical interaction ComPPI
LMNA TPX2 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
H2BC4 TPX2 25348397 N/A physical interaction ComPPI
CRK TPX2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SIAH2 TPX2 17716627 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RNF111 TPX2 25348397 N/A physical interaction ComPPI
PIK3R1 TPX2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
NCK1 TPX2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 TPX2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
JUN TPX2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
MAPK14 TPX2 25348397 N/A physical interaction ComPPI
FZR1 TPX2 25348397 N/A physical interaction ComPPI
KPNB1 TPX2 25348397 N/A physical interaction ComPPI
SERPINH1 TPX2 25348397 N/A physical interaction ComPPI
RPA1 TPX2 25348397 N/A physical interaction ComPPI
IKBKB TPX2 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AFAP1 TPX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 TPX2 25348397 N/A physical interaction ComPPI
RPA3 TPX2 25348397 N/A physical interaction ComPPI
CHUK TPX2 17939994 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
AURKA TPX2 12177045 14525934 14580337 19357306 20360068 22110403 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,x-ray crystallography,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
MDC1 TPX2 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 TPX2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HDAC9 TPX2 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF1 TPX2 25348397 N/A physical interaction ComPPI
HMMR TPX2 14525934 15705883 22110403 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
BRCA1 TPX2 22110403 24234451 25348397 29656893 association anti bait coimmunoprecipitation,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AURKB TPX2 25348397 N/A physical interaction ComPPI
PPIF TPX2 25348397 N/A physical interaction ComPPI
SAP130 TPX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SARNP TPX2 25348397 N/A physical interaction ComPPI
RBPJ TPX2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NAP1L1 TPX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ZNF598 TPX2 25348397 N/A physical interaction ComPPI
NDUFA7 TPX2 25348397 N/A physical interaction ComPPI
SCAMP3 TPX2 25348397 N/A physical interaction ComPPI
THAP11 TPX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
H2BC11 TPX2 25348397 N/A physical interaction ComPPI
IKBKG TPX2 25348397 N/A physical interaction ComPPI
TPX2 THUMPD2 25348397 N/A physical interaction ComPPI
TPX2 DNAJC8 25348397 N/A physical interaction ComPPI
TPX2 UBE2S 25348397 N/A physical interaction ComPPI
MRPL53 TPX2 25348397 N/A physical interaction ComPPI
TPX2 TPX2 12177045 14525934 N/A experimental interaction detection HPRD
MKI67 TPX2 24234451 26949251 association anti tag coimmunoprecipitation IntAct
AURKA TPX2 12177045 14580337 14600264 15630414 18773538 19357306 20360068 22110403 26186194 26240182 27898060 stimulant N/A OmniPath
TPX2 AURKA 12177045 14580337 14600264 15630414 18773538 19357306 20360068 22110403 26186194 27898060 stimulant N/A OmniPath
CDK1 TPX2 25688093 27898060 N/A N/A OmniPath
TPX2 HMMR 15705883 27898060 N/A N/A OmniPath

Visualization










  Return