GENE：BMP5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BMP5 |
| FullNmae | bone morphogenetic protein 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1072 |
| EnsembleID | ENSG00000112175 |
| Uniprot | P22003 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BMP5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BMP5 | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BMP5 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BMP5 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BMP5 | GO:0001501,GO:0001503,GO:0003272,GO:0003323,GO:0003344,GO:0005125,GO:0005515,GO:0005575,GO:0005615,GO:0005615,GO:0007389,GO:0008083,GO:0008284,GO:0008285,GO:0010719,GO:0010894,GO:0021502,GO:0030509,GO:0030539,GO:0030902,GO:0031982,GO:0032348,GO:0043569,GO:0043583,GO:0045944,GO:0048738,GO:0050679,GO:0051216,GO:0060037,GO:0060391,GO:0060411,GO:0060710,GO:0061384,GO:0070700,GO:0071676,GO:0097065,GO:1900006,GO:1902042,GO:1905069,GO:2000065 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| BMP5 | hsa:653 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| BMP5 | hsa:653 | path:hsa04350 | TGF-beta signaling pathway - Homo sapiens (human) |
| BMP5 | hsa:653 | path:hsa04390 | Hippo signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CEBPA | BMP5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BMP5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | BMP5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | BMP5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | BMP5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000075E2C3 | BMP5 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | BMP5 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | BMP5 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D860 | BMP5 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BMPR1A | BMP5 | 11580864 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| NOG | BMP5 | 11580864 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| FST | BMP5 | 11580864 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| BMP5 | HBB | 25348397 | N/A | physical interaction | ComPPI |
| BMP5 | VWA8 | 25348397 | N/A | physical interaction | ComPPI |
| BMP5 | ANKRD46 | 25348397 | N/A | physical interaction | ComPPI |
| CHRDL2 | BMP5 | 14525934 14660436 | N/A | experimental interaction detection | HPRD |