Gene Information gene info

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GENE：PLCG1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLCG1
FullNmae phospholipase C gamma 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9065
EnsembleID ENSG00000124181
Uniprot P19174

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLCG1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLCG1 pyroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PLCG1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PLCG1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLCG1 GO:0001701,GO:0001726,GO:0002862,GO:0004435,GO:0004435,GO:0004435,GO:0004629,GO:0004629,GO:0005168,GO:0005509,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0005911,GO:0007173,GO:0007173,GO:0008180,GO:0009395,GO:0010634,GO:0010634,GO:0016477,GO:0019722,GO:0019901,GO:0030027,GO:0030971,GO:0032587,GO:0035254,GO:0038095,GO:0042995,GO:0043536,GO:0045766,GO:0046488,GO:0048015,GO:0050429,GO:0050804,GO:0050852,GO:0051209,GO:0051281,GO:0071364,GO:0071364,GO:0098685,GO:0098978,GO:1905564,GO:2000353

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLCG1 hsa:5335 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04066 HIF-1 signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04360 Axon guidance - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04670 Leukocyte transendothelial migration - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04919 Thyroid hormone signaling pathway - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05012 Parkinson disease - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05110 Vibrio cholerae infection - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05131 Shigellosis - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05135 Yersinia infection - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05200 Pathways in cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05214 Glioma - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05223 Non-small cell lung cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
PLCG1 hsa:5335 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GRB2 PLCG1 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26192618 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483 interaction type N/A ACSN
PLCG1 GRAP 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26192618 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483 interaction type N/A ACSN
PLCG1 LAT 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26192618 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483 interaction type N/A ACSN
PLCG1 SRC 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26192618 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483 interaction type N/A ACSN
FLT1 PLCG1 10022831 11166270 11312102 11960372 12629515 13678960 15099563 15111329 15501236 15520864 15573129 16002046 16076871 16572188 17086423 18988627 19414323 21372296 22064427 22461508 23331499 23390297 24217602 24346288 25922287 26192618 26201938 8837607 9157999 9299537 9398617 9570538 9600074 9753319 interaction type,stimulation N/A ACSN,SignaLink,SignaLink
VEGFA PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
VEGFB PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
KDR PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
NCK1 PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
SHC1 PLCG1 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26192618 26201938 26552706 8551221 8837607 9157999 9570538 9753319 interaction type N/A ACSN
ITK PLCG1 10586033 11406363 11709089 12163161 12186560 12941616 15661896 23109003 23331499 25137453 26192618 interaction type,stimulation,chemical activation reaction N/A ACSN,SignaLink,SignaLink
CD247 PLCG1 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type N/A ACSN
ZAP70 PLCG1 10562324 10925299 11353765 11438547 11709089 11875494 12415267 12731048 12811837 12941616 15735648 16713974 17371980 20435894 20814939 21059766 23109003 23414611 23508573 23620508 23886063 24378531 26192618 7600293 8478617 8642247 9625766 9738502 interaction type,chemical activation reaction N/A ACSN,SignaLink
VAV1 PLCG1 10077632 10395673 10646608 10679059 10714681 10849438 10898494 11007481 11080163 11278486 11340169 11526404 11698448 11709089 11754814 11804587 11994416 12094222 12165654 12186560 12573241 12616499 12626562 12670394 12740575 12885870 12917349 12941616 14764585 15169881 16887996 17540168 19909365 20189481 22513334 22786724 22952938 23109003 24243840 25355530 25539813 26192618 26552706 29145629 7518558 8189062 8226994 8629002 8630736 8673706 8986718 9099726 9438848 interaction type,physical association,chemical activation reaction inferred by curator ACSN,Reactome,SignaLink
TEC PLCG1 11406363 15214048 26192618 interaction type N/A ACSN
CD101 PLCG1 26192618 9647226 interaction type N/A ACSN
PLCG1 LCP2 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26192618 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483 interaction type N/A ACSN
GAST PLCG1 10426994 10477091 11907067 15536084 16713974 23523669 24584707 26192618 7890616 9535722 interaction type N/A ACSN
SH2D1B PLCG1 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
SLAMF7 PLCG1 10426994 11907067 15536084 16339536 16713974 17599905 19151721 24687958 25312647 26192618 7890616 9535722 interaction type N/A ACSN
CD48 PLCG1 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
SH2D1A PLCG1 10358138 10359122 11390470 12515815 15169881 15713798 15905190 15998796 16081768 16177062 16339513 17171759 20189481 22683124 22786724 26192618 26794910 7890616 9535722 interaction type N/A ACSN
IL13 PLCG1 12223527 12401408 14610620 14657224 15099563 18250477 18451175 20184663 21097505 26192618 26755705 7890616 9535722 interaction type N/A ACSN
AXL PLCG1 23180781 9178760 physical association anti tag coimmunoprecipitation,far western blotting InnateDB
CD33 PLCG1 17947393 23180781 physical association pull down InnateDB
MAPT PLCG1 18467332 23180781 physical association pull down InnateDB
CD22 PLCG1 23180781 8627166 physical association anti tag coimmunoprecipitation InnateDB
PLCG1 CD22 23180781 8627166 physical association anti tag coimmunoprecipitation InnateDB
PLCG1 SYK 10026222 12573241 15161916 15184383 19592646 21659545 23180781 24243840 29145629 7517665 7518558 8627166 8629002 8630736 8657103 8702662 8986718 8995445 enzymatic reaction,physical association anti tag coimmunoprecipitation,inferred by curator InnateDB,Reactome
NFAT5 PLCG1 20080774 23180781 physical association anti tag coimmunoprecipitation InnateDB
AR PLCG1 20080774 23180781 physical association electrophoretic mobility supershift assay InnateDB
PLCG1 SELE 12960351 23180781 physical association anti tag coimmunoprecipitation InnateDB
PLCG1 ASAP2 17474147 23180781 physical association peptide array,pull down InnateDB
PLCG1 ABL2 17474147 23180781 physical association peptide array,pull down InnateDB
PLCG1 RIN3 17474147 23180781 physical association peptide array,pull down InnateDB
PLCG1 SHANK2 17474147 23180781 physical association peptide array,pull down InnateDB
PLCG1 MAP4K1 17474147 23180781 physical association anti tag coimmunoprecipitation,peptide array,pull down InnateDB
PLCG1 SOS2 17474147 23180781 physical association anti tag coimmunoprecipitation,peptide array,pull down InnateDB
PLCG1 ASAP1 17474147 23180781 physical association anti tag coimmunoprecipitation,peptide array,pull down InnateDB
PLCG1 CAST 17474147 23180781 physical association peptide array InnateDB
PLCG1 DUSP15 17474147 23180781 physical association peptide array InnateDB
PLCG1 DLX4 17474147 23180781 physical association peptide array InnateDB
PLCG1 TRAIP 17474147 23180781 physical association peptide array InnateDB
PLCG1 SNX17 17474147 23180781 physical association peptide array InnateDB
PLCG1 PDIA2 17474147 23180781 physical association peptide array InnateDB
PLCG1 SLC23A1 17474147 23180781 physical association peptide array InnateDB
PLCG1 ARHGEF11 17474147 23180781 physical association peptide array InnateDB
PLCG1 EXTL3 17474147 23180781 physical association peptide array InnateDB
PLCG1 RPL13 17474147 23180781 physical association peptide array InnateDB
PLCG1 RRAS 17474147 23180781 physical association peptide array InnateDB
PLCG1 EFS 17474147 23180781 physical association peptide array InnateDB
PLCG1 GHR 17474147 23180781 physical association peptide array InnateDB
PLCG1 RYR1 17474147 23180781 physical association peptide array InnateDB
PLCG1 RGS7 17474147 23180781 physical association peptide array InnateDB
PLCG1 CKAP5 17474147 23180781 physical association peptide array InnateDB
PLCG1 JAK2 17474147 23180781 physical association peptide array InnateDB
PLCG1 SOS1 10026222 10811803 11390650 12471105 17474147 19592646 20484116 23180781 24243840 29145629 8702662 8995445 physical association peptide array,inferred by curator InnateDB,Reactome
PLCG1 FLNB 17474147 23180781 physical association peptide array InnateDB
PLCG1 ID4 17474147 23180781 physical association peptide array InnateDB
PLCG1 FLNA 17474147 23180781 physical association peptide array InnateDB
PLCG1 IL3RA 17474147 23180781 physical association peptide array InnateDB
PLCG1 ABL1 17474147 23180781 physical association peptide array InnateDB
PLCG1 SUV39H2 17474147 23180781 physical association peptide array InnateDB
PLCG1 SEC24B 17474147 23180781 physical association peptide array InnateDB
PLCG1 ZP2 17474147 23180781 physical association peptide array InnateDB
PLCG1 FCGR2B 17474147 23180781 physical association peptide array InnateDB
PLCG1 PHACTR2 17474147 23180781 physical association peptide array InnateDB
PLCG1 CSMD2 17474147 23180781 physical association peptide array InnateDB
PLCG1 SERPINC1 17474147 23180781 physical association peptide array InnateDB
PLCG1 FANCA 17474147 23180781 physical association peptide array InnateDB
PLCG1 TGOLN2 17474147 23180781 physical association peptide array InnateDB
PLCG1 CHAF1A 17474147 23180781 physical association peptide array InnateDB
PLCG1 MAP4 17474147 23180781 physical association peptide array InnateDB
PLCG1 TDRD1 17474147 23180781 physical association peptide array InnateDB
PLCG1 AFF2 17474147 23180781 physical association peptide array InnateDB
PLCG1 AIRE 17474147 23180781 physical association peptide array InnateDB
PLCG1 LIG3 17474147 23180781 physical association peptide array InnateDB
PLCG1 NELFB 17474147 23180781 physical association peptide array InnateDB
PLCG1 SNX7 17474147 23180781 physical association peptide array InnateDB
PLCG1 RAG1 17474147 23180781 physical association peptide array InnateDB
PLCG1 DTNBP1 17474147 23180781 physical association peptide array InnateDB
PLCG1 EPX 17474147 23180781 physical association peptide array InnateDB
PLCG1 FLNC 17474147 23180781 physical association peptide array InnateDB
PLCG1 MEPE 17474147 23180781 physical association peptide array InnateDB
PLCG1 DLGAP1 17474147 23180781 physical association peptide array InnateDB
PLCG1 SPEN 17474147 23180781 physical association peptide array InnateDB
PLCG1 PPFIA4 17474147 23180781 physical association peptide array InnateDB
PLCG1 ADNP 17474147 23180781 physical association peptide array InnateDB
PLCG1 F2RL2 17474147 23180781 physical association peptide array InnateDB
PLCG1 DLGAP3 17474147 23180781 physical association peptide array InnateDB
LYN PLCG1 15644415 29145629 8034732 physical association inferred by curator Reactome
PLCG1 IRS2 15644415 29145629 8034732 physical association inferred by curator Reactome
IGKC PLCG1 15161916 29145629 7517665 8657103 physical association inferred by curator Reactome
PLCG1 BTK 12573241 15184383 15365099 21659545 24243840 29145629 7518558 8629002 8630736 8986718 enzymatic reaction,physical association inferred by curator Reactome
HLA-DRA PLCG1 11048639 29145629 enzymatic reaction inferred by curator Reactome
HLA-DQA2 PLCG1 11048639 29145629 enzymatic reaction inferred by curator Reactome
HLA-DQA1 PLCG1 11048639 29145629 enzymatic reaction inferred by curator Reactome
PLCG1 HLA-DPA1 11048639 29145629 enzymatic reaction inferred by curator Reactome
NTRK1 PLCG1 10092678 10708759 1715690 18988627 21071413 23331499 8384556 stimulation N/A SignaLink,SignaLink
PDGFRA PLCG1 23331499 7535778 stimulation N/A SignaLink
PDGFRB PLCG1 23331499 7535778 8443409 stimulation N/A SignaLink
NTRK3 PLCG1 10092678 23331499 7657612 8344249 stimulation N/A SignaLink
LTK PLCG1 23331499 8084603 stimulation N/A SignaLink
ALK PLCG1 11888936 14968112 23331499 stimulation N/A SignaLink
LCP2 PLCG1 11390650 11709089 12941616 16467851 23109003 23331499 stimulation,chemical activation reaction N/A SignaLink,SignaLink
RHOA PLCG1 12071848 23331499 stimulation N/A SignaLink
GIT1 PLCG1 14523024 23331499 stimulation N/A SignaLink
GAB1 PLCG1 11507676 23331499 8596638 stimulation N/A SignaLink
GRAP PLCG1 23331499 9281317 stimulation N/A SignaLink
ERBB2 PLCG1 1676673 1683701 23331499 stimulation N/A SignaLink
EGFR PLCG1 12601080 15144186 1689310 23331499 7682059 8657103 8885868 9207933 stimulation N/A SignaLink
EEF1A1 PLCG1 11886851 23331499 stimulation N/A SignaLink
LAT PLCG1 11709089 12941616 15219999 15286727 23109003 chemical activation reaction N/A SignaLink
CBL PLCG1 11709089 12941616 23109003 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
BLNK PLCG1 20005715 interaction type N/A PSP
DAB1 PLCG1 20005715 interaction type N/A PSP
DOK1 PLCG1 20005715 interaction type N/A PSP
EFS PLCG1 20005715 interaction type N/A PSP,SignaLink
FLNB PLCG1 20005715 interaction type N/A PSP,SignaLink
GAB1 PLCG1 20005715 interaction type N/A PSP,SignaLink
GRAP PLCG1 20005715 interaction type N/A PSP
GRB2 PLCG1 20005715 21071413 9281317 interaction type N/A PSP,SignaLink
IRS2 PLCG1 18988627 20005715 21071413 9535722 interaction type N/A PSP,SignaLink
LAT PLCG1 11368773 16467851 18988627 20005715 21071413 9729044 interaction type N/A PSP,SignaLink
LAT2 PLCG1 20005715 interaction type N/A PSP,SignaLink
LCP2 PLCG1 20005715 interaction type N/A PSP
NCK1 PLCG1 20005715 interaction type N/A PSP
RGS7 PLCG1 20005715 interaction type N/A PSP,SignaLink
SH2B3 PLCG1 20005715 interaction type N/A PSP,SignaLink
SH2D2A PLCG1 20005715 interaction type N/A PSP
SH3BP2 PLCG1 20005715 interaction type N/A PSP
SHANK2 PLCG1 20005715 interaction type N/A PSP,SignaLink
SHANK3 PLCG1 20005715 interaction type N/A PSP,SignaLink
SHB PLCG1 20005715 interaction type N/A PSP
SHC1 PLCG1 20005715 interaction type N/A PSP
SNX17 PLCG1 20005715 interaction type N/A PSP,SignaLink
SOCS7 PLCG1 20005715 interaction type N/A PSP
TRAIP PLCG1 20005715 interaction type N/A PSP,SignaLink
DAB1 PLCG1 15062102 18988627 20005715 20005715 N/A N/A SignaLink
DOK1 PLCG1 20005715 20005715 N/A N/A SignaLink
NCK1 PLCG1 18988627 20005715 20005715 9314836 N/A N/A SignaLink
SHB PLCG1 12084069 18988627 20005715 20005715 N/A N/A SignaLink
GRAP PLCG1 20005715 20005715 N/A N/A SignaLink
LCP2 PLCG1 20005715 20005715 N/A N/A SignaLink
SHC1 PLCG1 20005715 20005715 N/A N/A SignaLink
BLNK PLCG1 20005715 20005715 N/A N/A SignaLink
SH2D2A PLCG1 20005715 20005715 N/A N/A SignaLink
SH3BP2 PLCG1 11390470 11390470 18988627 20005715 20005715 21071413 N/A N/A SignaLink
SOCS7 PLCG1 18988627 20005715 20005715 9344857 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR PLCG1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PLCG1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PLCG1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PLCG1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PLCG1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TAL1 PLCG1 20028976 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C PLCG1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PLCG1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PLCG1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 PLCG1 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000EC1BE PLCG1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075D1FC PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PLCG1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF PLCG1 22100165 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 PLCG1 22100165 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027080C PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 PLCG1 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 PLCG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 PLCG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 PLCG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 PLCG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B PLCG1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 PLCG1 25416803 25964059 mrna cleavage,inhibition array technology,quantitative reverse transcription pcr TarBase
URS0000302909 PLCG1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000338542 PLCG1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000060B2B PLCG1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E177F PLCG1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SYK PLCG1 22135298 phosphorylation N/A PhosphoSite
PRKACA PLCG1 22135298 phosphorylation N/A PhosphoSite
ABL1 PLCG1 22135298 phosphorylation N/A PhosphoSite
ITK PLCG1 22135298 phosphorylation N/A PhosphoSite
PRKCA PLCG1 22135298 phosphorylation N/A PhosphoSite
EGFR PLCG1 22135298 phosphorylation N/A PhosphoSite
RET PLCG1 22135298 phosphorylation N/A PhosphoSite
AKT1 PLCG1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HNRNPK PLCG1 25348397 N/A physical interaction ComPPI
LCP2 PLCG1 11390650 14525934 15929943 16467851 21725281 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
RNF40 PLCG1 25348397 N/A physical interaction ComPPI
SPRY1 PLCG1 25348397 N/A physical interaction ComPPI
LAT PLCG1 10811803 11368773 14525934 16467851 16938345 24234451 24642916 25348397 9489702 9729044 association,physical association anti bait coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,pull down,surface plasmon resonance,physical interaction ComPPI,HPRD,IntAct
BAG3 PLCG1 10980614 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LZTS2 PLCG1 25348397 N/A physical interaction ComPPI
NPM1 PLCG1 25348397 N/A physical interaction ComPPI
AGTR1 PLCG1 24234451 25348397 9516477 association pull down ComPPI,IntAct
WAS PLCG1 14525934 24234451 25348397 8892607 physical association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
SLC23A1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PTPN6 PLCG1 25348397 N/A physical interaction ComPPI
KHDRBS2 PLCG1 25348397 N/A physical interaction ComPPI
RAC1 PLCG1 19264842 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down ComPPI,IntAct
RACK1 PLCG1 14525934 25348397 8290562 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ERBB2 PLCG1 14525934 16273093 1676673 1683701 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction ComPPI,HPRD,IntAct
PAK1 PLCG1 25348397 N/A physical interaction ComPPI
CBL PLCG1 12061819 14525934 16467851 24234451 25241761 25348397 9234717 9712732 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
VAV1 PLCG1 14525934 16467851 25348397 9891995 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SYK PLCG1 14525934 15144186 1689310 24234451 25348397 7682059 8657103 8885868 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
SHB PLCG1 12084069 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SH3BP2 PLCG1 11390470 14525934 15345594 24234451 25348397 association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
BLNK PLCG1 14525934 25348397 9697839 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PECAM1 PLCG1 25348397 N/A physical interaction ComPPI
MST1R PLCG1 14525934 25348397 8918464 N/A experimental interaction detection,physical interaction ComPPI,HPRD
KIT PLCG1 14525934 24234451 24728074 25241761 25348397 7536744 7537096 association,physical association coimmunoprecipitation,experimental interaction detection,fluorescence polarization spectroscopy,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
PIK3R1 PLCG1 24234451 25348397 9020117 physical association pull down ComPPI,IntAct
PTPN11 PLCG1 14525934 15563458 24234451 25348397 27898060 9020117 physical association experimental interaction detection,pull down ComPPI,HPRD,IntAct,OmniPath
SRC PLCG1 14525934 1689310 25348397 7510703 7682059 8657103 8885868 N/A experimental interaction detection,physical interaction ComPPI,HPRD
DOK1 PLCG1 11071635 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SH2B3 PLCG1 25348397 N/A physical interaction ComPPI
FLT1 PLCG1 11312102 14525934 23397142 24234451 25348397 9299537 9398617 9600074 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
KDR PLCG1 12598525 14525934 24234451 25348397 association experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
PLCG2 PLCG1 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
SHC1 PLCG1 10652211 14525934 25348397 8155326 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SOS1 PLCG1 10913276 14525934 17474147 24234451 25348397 9020117 physical association experimental interaction detection,fluorescence technology,peptide array,pull down,physical interaction ComPPI,HPRD,IntAct
RRAS PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
EPHB2 PLCG1 25348397 N/A physical interaction ComPPI
MAP4K1 PLCG1 17474147 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence technology,peptide array,pull down ComPPI,IntAct
KHDRBS1 PLCG1 14525934 24234451 25348397 7537265 7799925 9045636 9743338 physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
GAB2 PLCG1 25348397 N/A physical interaction ComPPI
FCGR2B PLCG1 17474147 24234451 25348397 physical association fluorescence technology,peptide array ComPPI,IntAct
GRB2 PLCG1 14525934 21706016 24234451 25348397 9020117 9281317 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction ComPPI,HPRD,IntAct
AR PLCG1 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
PRKD1 PLCG1 14525934 25348397 8885868 N/A experimental interaction detection,physical interaction ComPPI,HPRD
NELFB PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FGFR2 PLCG1 24234451 25241761 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescent resonance energy transfer,pull down,physical interaction,proximity ligation assay,microscale thermophoresis ComPPI,IntAct
FLNC PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
ZAP70 PLCG1 14525934 25348397 7629168 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ITK PLCG1 10586033 12163161 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
RHOA PLCG1 12071848 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
FLNA PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PKN2 PLCG1 14525934 25348397 8910519 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ARHGEF11 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
ARHGEF2 PLCG1 25348397 N/A physical interaction ComPPI
SERPINC1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PDGFRB PLCG1 11896612 1396585 14525934 15641795 23063561 23397142 24234451 25348397 8443409 association,physical association biophysical,coimmunoprecipitation,experimental interaction detection,nuclear magnetic resonance,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
IRS2 PLCG1 14525934 22974441 25348397 27898060 9535722 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
GHR PLCG1 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
GAB1 PLCG1 14525934 24234451 24728074 25348397 8596638 N/A experimental interaction detection,fluorescence polarization spectroscopy,physical interaction ComPPI,HPRD,IntAct
PFKP PLCG1 25348397 N/A physical interaction ComPPI
PDGFRA PLCG1 14525934 24234451 25241761 25348397 7535778 association,physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
NTRK1 PLCG1 14525934 1715690 24234451 25348397 8384556 association coimmunoprecipitation,experimental interaction detection,physical interaction,competition binding ComPPI,HPRD,IntAct
TUB PLCG1 10455176 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SOS2 PLCG1 10940929 14525934 17474147 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,fluorescence technology,peptide array,physical interaction,two hybrid ComPPI,HPRD,IntAct
DGKZ PLCG1 12890670 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PLD2 PLCG1 12646582 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PICALM PLCG1 10926122 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
GIT1 PLCG1 14523024 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LAT2 PLCG1 25348397 N/A physical interaction ComPPI
TNK1 PLCG1 10873601 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TRPM7 PLCG1 11941371 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
JAK1 PLCG1 25348397 N/A physical interaction ComPPI
PDGFA PLCG1 25348397 N/A physical interaction ComPPI
CAV1 PLCG1 20808760 24234451 25348397 association protein array,pull down,physical interaction ComPPI,IntAct
SNX17 PLCG1 17474147 24234451 25348397 physical association fluorescence technology,peptide array ComPPI,IntAct
DLGAP1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CHAF1A PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HNRNPU PLCG1 25348397 N/A coimmunoprecipitation,physical interaction ComPPI
NTRK2 PLCG1 12419535 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
AKAP2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
F2RL2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
EEF1A1 PLCG1 11886851 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
RYR1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
HNRNPL PLCG1 25348397 N/A physical interaction ComPPI
RGS7 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RIN3 PLCG1 17474147 24234451 25348397 physical association fluorescence technology,peptide array,pull down ComPPI,IntAct
RAG1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SELE PLCG1 12960351 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
UNC45A PLCG1 25348397 N/A physical interaction ComPPI
MET PLCG1 14525934 24234451 24728074 25348397 7513258 8662733 N/A experimental interaction detection,fluorescence polarization spectroscopy ComPPI,HPRD,IntAct
ABI1 PLCG1 20598684 24234451 25348397 N/A array technology ComPPI,IntAct
ZP2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RET PLCG1 14525934 16153436 24234451 25241761 25348397 8628282 association,physical association experimental interaction detection,physical interaction,competition binding,proximity ligation assay ComPPI,HPRD,IntAct
AXL PLCG1 14525934 24234451 25348397 9178760 association coimmunoprecipitation,experimental interaction detection,far western blotting ComPPI,HPRD,IntAct
SYNCRIP PLCG1 25348397 N/A physical interaction ComPPI
EGFR PLCG1 12601080 14525934 14568990 15144186 16273093 1689310 24234451 25348397 7682059 7693694 7993895 8657103 8885868 9020117 9207933 association,physical association coimmunoprecipitation,cross-linking study,experimental interaction detection,far western blotting,protein array,pull down,physical interaction ComPPI,HPRD,IntAct
EPOR PLCG1 14525934 15329338 15953601 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
FGFR1 PLCG1 1656221 20932831 23063561 24234451 25241761 25348397 8321198 phosphorylation reaction,association,physical association anti bait coimmunoprecipitation,bioluminescence resonance energy transfer,isothermal titration calorimetry,pull down,phosphorylation reaction,physical interaction,protein kinase assay,proximity ligation assay ComPPI,IntAct
RAB11A PLCG1 25348397 N/A physical interaction ComPPI
RASA1 PLCG1 24234451 25348397 9020117 physical association pull down,physical interaction ComPPI,IntAct
FYB1 PLCG1 22074159 24234451 25348397 association pull down ComPPI,IntAct
JAK2 PLCG1 17474147 24234451 25348397 physical association peptide array,physical interaction ComPPI,IntAct
SCARB2 PLCG1 25348397 N/A pull down ComPPI
ASAP1 PLCG1 17474147 24234451 25348397 physical association anti bait coimmunoprecipitation,fluorescence technology,peptide array ComPPI,IntAct
STRAP PLCG1 25348397 N/A physical interaction ComPPI
TRAIP PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
NCKIPSD PLCG1 25348397 N/A physical interaction ComPPI
LIG3 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FLNB PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PYGB PLCG1 25348397 N/A physical interaction ComPPI
PRKN PLCG1 25348397 N/A physical interaction ComPPI
DLX4 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
IBTK PLCG1 25348397 N/A physical interaction ComPPI
PDIA2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
ASAP2 PLCG1 17474147 24234451 25348397 physical association fluorescence technology,peptide array,pull down ComPPI,IntAct
IL3RA PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CD244 PLCG1 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
SPEN PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
EFS PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
AIRE PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
DOK2 PLCG1 25348397 N/A physical interaction ComPPI
ID4 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
INSR PLCG1 11796522 14525934 14568990 24234451 25348397 9593725 colocalization,physical association coimmunoprecipitation,cross-linking study,experimental interaction detection,pull down,physical interaction,fluorescence microscopy ComPPI,HPRD,IntAct
CAST PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
SH2D1B PLCG1 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
DDIT4 PLCG1 19557001 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RIC8A PLCG1 25348397 N/A physical interaction ComPPI
CACNB3 PLCG1 25348397 N/A physical interaction ComPPI
NCAM1 PLCG1 25348397 N/A physical interaction ComPPI
PLXNB1 PLCG1 25348397 N/A physical interaction ComPPI
DTNBP1 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
AKT1 PLCG1 16525023 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
KCNJ5 PLCG1 25348397 N/A physical interaction ComPPI
PML PLCG1 25348397 N/A physical interaction ComPPI
CKAP5 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RPL13 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
TGOLN2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
FAS PLCG1 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
NELL1 PLCG1 21723284 24234451 25348397 physical association phage display ComPPI,IntAct
GTF3C4 PLCG1 25348397 N/A physical interaction ComPPI
PLXNB2 PLCG1 25348397 N/A physical interaction ComPPI
NFAT5 PLCG1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
SEC24B PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PPFIA4 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
DPP7 PLCG1 25348397 N/A physical interaction ComPPI
ABL2 PLCG1 17474147 24234451 25348397 physical association fluorescence technology,peptide array,pull down ComPPI,IntAct
UCHL5 PLCG1 25348397 N/A physical interaction ComPPI
SARNP PLCG1 25348397 N/A physical interaction ComPPI
HCK PLCG1 10586033 14525934 15144186 1689310 23397142 24234451 25348397 7682059 8657103 8885868 physical association experimental interaction detection,proximity ligation assay ComPPI,HPRD,IntAct
MAP4 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
WDR61 PLCG1 25348397 N/A physical interaction ComPPI
RHOU PLCG1 14525934 15556869 24234451 25348397 physical association experimental interaction detection,pull down ComPPI,HPRD,IntAct
LIMD1 PLCG1 25348397 N/A physical interaction ComPPI
GSN PLCG1 25348397 N/A physical interaction ComPPI
ALK PLCG1 14525934 25348397 9174053 N/A experimental interaction detection,physical interaction ComPPI,HPRD
VIL1 PLCG1 12937273 14525934 16921170 17229814 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer ComPPI,HPRD,IntAct,OmniPath
MCMBP PLCG1 25348397 N/A physical interaction ComPPI
SUV39H2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CCDC120 PLCG1 25348397 N/A physical interaction ComPPI
SNX7 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
AASDHPPT PLCG1 25348397 N/A physical interaction ComPPI
ISG20L2 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CD22 PLCG1 14525934 24234451 25348397 8627166 association,physical association coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
CTPS1 PLCG1 25348397 N/A physical interaction ComPPI
DLGAP3 PLCG1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
RPL38 PLCG1 25348397 N/A physical interaction ComPPI
LTK PLCG1 25348397 N/A physical interaction ComPPI
EEF1A1P5 PLCG1 25348397 N/A physical interaction ComPPI
PLCG1 PTK2 23397142 24234451 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
PLCG1 ARHGAP32 12454018 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PLCG1 NTRK3 14525934 25348397 7657612 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PLCG1 PTPRJ 11259588 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PLCG1 ABL1 1383690 14525934 17474147 24234451 25348397 physical association experimental interaction detection,peptide array,physical interaction ComPPI,HPRD,IntAct
PLCG1 CAMK2A 25348397 N/A physical interaction ComPPI
PLCG1 NTMT1 25348397 N/A physical interaction ComPPI
PLCG1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PLCG1 EHD4 25348397 N/A physical interaction ComPPI
PLCG1 NXF1 25348397 N/A physical interaction ComPPI
PLCG1 MVB12B 25348397 N/A physical interaction ComPPI
PLCG1 GAS2L1 25348397 N/A physical interaction ComPPI
PLCG1 SNX11 25348397 N/A physical interaction ComPPI
PLCG1 TEKT2 25348397 N/A physical interaction ComPPI
PLCG1 LDLRAD4 25348397 N/A physical interaction ComPPI
PLCG1 NPEPL1 25348397 N/A physical interaction ComPPI
PLCG1 SKIV2L 25348397 N/A physical interaction ComPPI
PLCG1 TIPRL 25348397 N/A physical interaction ComPPI
PLCG1 TTC9B 25348397 N/A physical interaction ComPPI
PLCG1 ZNF785 25348397 N/A physical interaction ComPPI
PLCG1 SHANK2 17474147 24234451 25348397 physical association fluorescence technology,peptide array,pull down ComPPI,IntAct
PLCG1 DUSP15 17474147 24234451 25348397 physical association fluorescence technology,peptide array ComPPI,IntAct
PLCG1 SHANK3 17474147 24234451 25348397 physical association fluorescence technology,peptide array ComPPI,IntAct
PLCG1 EXTL3 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 FCGR2C 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 PHACTR2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 CSMD2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 FANCA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 TDRD1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 AFF2 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 EPX 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 MEPE 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 BICRA 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 ADNP 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLCG1 PLD1 19323535 24234451 25348397 N/A atomic force microscopy ComPPI,IntAct
PLCG1 TESPA1 22561606 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PLCG1 THEMIS 21189249 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
UBR7 PLCG1 25348397 N/A physical interaction ComPPI
HAVCR2 PLCG1 24234451 25348397 26492563 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
HSCB PLCG1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
LYN PLCG1 10586033 14525934 15144186 1689310 7682059 8657103 8885868 N/A experimental interaction detection HPRD
CD28 PLCG1 14525934 27898060 8386518 N/A experimental interaction detection HPRD,OmniPath
GTF2H1 PLCG1 10467411 14525934 N/A experimental interaction detection HPRD
SYN1 PLCG1 10899172 14525934 N/A experimental interaction detection HPRD
PITPNA PLCG1 14525934 7761838 N/A experimental interaction detection HPRD
DDR1 PLCG1 10783152 14525934 N/A experimental interaction detection HPRD
DAB1 PLCG1 14525934 15062102 N/A experimental interaction detection HPRD
AGAP2 PLCG1 11823862 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
VAV3 PLCG1 11094073 14525934 N/A experimental interaction detection HPRD
SNAP91 PLCG1 11779129 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath
SOCS7 PLCG1 14525934 9344857 N/A experimental interaction detection HPRD
TRPC3 PLCG1 14525934 15744307 15766521 N/A experimental interaction detection,two hybrid HPRD
PLCG1 CTSS 14525934 27898060 9164868 N/A experimental interaction detection HPRD,OmniPath
BCR PLCG1 1383690 14525934 N/A experimental interaction detection HPRD
NCK1 PLCG1 14525934 9314836 N/A experimental interaction detection HPRD
ARHGEF5 PLCG1 14525934 9314836 N/A experimental interaction detection HPRD
FGFR4 PLCG1 14525934 7518429 N/A experimental interaction detection HPRD
PLCG1 BTK 14525934 15184383 N/A experimental interaction detection HPRD
PLCG1 TEC 10823839 14525934 N/A experimental interaction detection HPRD
PLCG1 DNM1 14525934 15252117 N/A experimental interaction detection HPRD
PLCG1 GRAP 14525934 8995379 N/A experimental interaction detection HPRD
PLCG1 SH2D2A 10692392 14525934 N/A experimental interaction detection HPRD
PLCG1 DAPP1 10770799 14525934 N/A experimental interaction detection HPRD
PLCG1 INPP5D 14525934 15953601 N/A experimental interaction detection HPRD
PLCG1 GRIN1 14525934 16767099 N/A experimental interaction detection HPRD
PLCG1 FYN 10586033 14525934 N/A experimental interaction detection HPRD
GRIN2B PLCG1 14525934 9231720 N/A experimental interaction detection HPRD
GRIN2A PLCG1 14525934 9231720 N/A experimental interaction detection HPRD
PLCG1 LIFR 14525934 27898060 7512571 N/A experimental interaction detection HPRD,OmniPath
PLCG1 LCK 14525934 1500851 N/A experimental interaction detection HPRD
PLCG1 PLCG1 11434923 24234451 dephosphorylation reaction biochemical IntAct
PLCG1 CEBPZ 10779349 27898060 N/A N/A OmniPath
USO1 PLCG1 12507498 27898060 N/A N/A OmniPath
SRC PLCG1 16497976 1689310 17016520 17389395 20068231 27898060 7510703 7682059 8388373 8657103 8885868 stimulant N/A OmniPath
PRKACA PLCG1 1370476 2479646 27898060 inhibition N/A OmniPath
LCK PLCG1 1500851 27898060 7682059 stimulant N/A OmniPath
PRKCA PLCG1 12601080 12645577 1370476 16038803 1708307 27898060 inhibition,stimulant N/A OmniPath
PLCG1 PRKCA 12645577 1370476 27898060 stimulant N/A OmniPath
LYN PLCG1 10586033 15144186 16497976 1689310 17016520 17389395 20068231 27898060 7682059 8657103 8885868 stimulant N/A OmniPath
PTPN1 PLCG1 21123182 27898060 N/A N/A OmniPath
PRKD1 PLCG1 1370476 19651622 20068231 27898060 8885868 inhibition,stimulant N/A OmniPath
PLCG1 TRPM7 11941371 27898060 inhibition N/A OmniPath
FYN PLCG1 10586033 27898060 7682059 stimulant N/A OmniPath
PLCG1 TRPC1 15654973 27898060 stimulant N/A OmniPath
PLCG1 FLNA 17474147 27898060 N/A N/A OmniPath
NTRK1 PLCG1 10092678 10708759 1715690 25921289 27898060 8384556 8552402 9856458 stimulant N/A OmniPath
EGFR PLCG1 11983899 12029091 12061819 12601080 12648464 12730118 12803489 12952950 14523024 14568990 15144186 15509800 15623534 15975899 16081816 16273093 16497976 16525023 16713569 1689310 17016520 17148460 17389395 17561374 19901323 20068231 21760611 22847294 23778885 24412752 2472219 24797263 27898060 7682059 7693694 7805859 7993895 8657103 8885868 9020117 9176240 9207933 9756944 stimulant N/A OmniPath
HCK PLCG1 10586033 15144186 16497976 1689310 17016520 17389395 18707149 20068231 23397142 27898060 7682059 8657103 8885868 stimulant N/A OmniPath
PLCG1 TRPC3 12437926 15744307 15766521 18276585 27898060 stimulant N/A OmniPath
RHOA PLCG1 12071848 27898060 stimulant N/A OmniPath
PLCG1 IL3RA 17474147 27898060 N/A N/A OmniPath
PTPRF PLCG1 11121408 27898060 inhibition N/A OmniPath
RET PLCG1 16153436 16497976 1689310 17016520 17389395 20068231 25241761 27898060 7682059 8628282 8657103 8885868 N/A N/A OmniPath
PDGFRB PLCG1 11896612 1396585 15641795 22974441 23063561 23397142 2472219 27898060 7486683 7535778 8443409 stimulant N/A OmniPath
KDR PLCG1 10672011 12598525 16835467 27898060 stimulant N/A OmniPath
LAT PLCG1 10811803 11368773 16467851 16938345 24642916 27898060 9489702 9729044 stimulant N/A OmniPath
AKT1 PLCG1 1370476 16525023 27898060 N/A N/A OmniPath
PLCG1 SOS1 10913276 10940929 17474147 27898060 9020117 stimulant N/A OmniPath
SOS1 PLCG1 10913276 10940929 17474147 27898060 9020117 N/A N/A OmniPath
GAB1 PLCG1 11507676 24728074 27898060 8596638 stimulant N/A OmniPath
ABL1 PLCG1 12652307 1383690 17474147 20841568 27898060 inhibition N/A OmniPath
CDK1 PLCG1 1370476 27898060 N/A N/A OmniPath
ERBB2 PLCG1 16273093 1676673 1683701 27898060 stimulant N/A OmniPath
PLCG1 GHR 17474147 27898060 N/A N/A OmniPath
EEF1A1 PLCG1 11886851 12898421 27898060 stimulant N/A OmniPath
PLCG1 RRAS 17474147 27898060 N/A N/A OmniPath
PLCG1 MAPT 18467332 27898060 N/A N/A OmniPath
JAK2 PLCG1 17474147 27898060 stimulant N/A OmniPath
FLT1 PLCG1 11312102 23397142 27898060 9299537 9398617 9600074 stimulant N/A OmniPath
LCP2 PLCG1 1139065 11390650 15929943 16467851 27898060 stimulant N/A OmniPath
NTRK3 PLCG1 10092678 10235685 27898060 7657612 8344249 stimulant N/A OmniPath
LTK PLCG1 27898060 8084603 stimulant N/A OmniPath
PLCG1 FLNC 17474147 27898060 N/A N/A OmniPath
SYK PLCG1 12601080 15144186 15592455 16038803 16126727 16497976 1689310 17016520 17081983 1708307 17389395 19534553 19690332 20068231 27898060 7682059 7744830 7831290 7991458 8627166 8657103 8885868 stimulant N/A OmniPath
PDGFRA PLCG1 25241761 27898060 7535778 stimulant N/A OmniPath
PLCG1 FLNB 17474147 27898060 N/A N/A OmniPath
PLCG1 SOS2 10940929 17474147 27898060 N/A N/A OmniPath
SOS2 PLCG1 10940929 17474147 27898060 N/A N/A OmniPath
GRAP PLCG1 27898060 8995379 9281317 stimulant N/A OmniPath
PLCG1 MAP4K1 17474147 27898060 N/A N/A OmniPath
ITK PLCG1 10586033 11564877 1216316 12163161 15215251 15951569 17389395 19534553 19690332 20519342 27898060 8657103 stimulant N/A OmniPath
GNGT1 PLCG1 23074268 27898060 stimulant N/A OmniPath
ALK PLCG1 11888936 1496811 14968112 27898060 9174053 9819383 stimulant N/A OmniPath
GIT1 PLCG1 14523024 27898060 stimulant N/A OmniPath
GRIN2A PLCG1 27898060 9231720 stimulant N/A OmniPath
GNG3 PLCG1 23074268 27898060 stimulant N/A OmniPath
GNB3 PLCG1 23074268 27898060 stimulant N/A OmniPath
GNG2 PLCG1 23074268 27898060 stimulant N/A OmniPath
PTPRJ PLCG1 11259588 27898060 inhibition N/A OmniPath

Visualization










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