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GENE：RBL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RBL1
FullNmae RB transcriptional corepressor like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9893
EnsembleID ENSG00000080839
Uniprot P28749

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RBL1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RBL1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RBL1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RBL1 GO:0000122,GO:0000785,GO:0000977,GO:0005515,GO:0005654,GO:0005654,GO:0005667,GO:0006325,GO:0007049,GO:0010629,GO:0030154,GO:0043550,GO:1990841,GO:2000134,GO:2000773

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RBL1 hsa:5933 path:hsa04110 Cell cycle - Homo sapiens (human)
RBL1 hsa:5933 path:hsa04218 Cellular senescence - Homo sapiens (human)
RBL1 hsa:5933 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
RBL1 hsa:5933 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
RBL1 hsa:5933 path:hsa05203 Viral carcinogenesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PHB RBL1 10523633 23180781 physical association anti tag coimmunoprecipitation InnateDB
BECN1 RBL1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBL1 SNX19 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 RBL1 11564866 23180781 physical association anti tag coimmunoprecipitation InnateDB
BEGAIN RBL1 16189514 23180781 physical association pull down InnateDB
PA2G4 RBL1 21085677 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBL1 L3MBTL1 20622854 23180781 physical association anti tag coimmunoprecipitation InnateDB
PHF8 RBL1 20622854 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBL1 HCFC1 20622854 23180781 physical association anti tag coimmunoprecipitation InnateDB
SETD1A RBL1 20622854 23180781 physical association anti tag coimmunoprecipitation InnateDB
IRF3 RBL1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 RBL1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 RBL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RBL1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RBL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ARID3A RBL1 23659165 trascriptional regulation,stimulation inferred by curator TFlink
RB1 RBL1 9671466 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RBL1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYB RBL1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 RBL1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002075FA RBL1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000042E1F RBL1 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00002075FA RBL1 21283765 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS0000042E1F RBL1 21283765 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000600E6 RBL1 21283765 24166509 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003808EC RBL1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 RBL1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D RBL1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 RBL1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C RBL1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 RBL1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000096022 RBL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 RBL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 RBL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000018D2BE RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RBL1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 RBL1 22135298 phosphorylation N/A PhosphoSite
CDK4 RBL1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GOLGA2 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNW1 RBL1 12466551 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
DYNLL1 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CD2BP2 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CCND1 RBL1 14525934 25348397 8643455 N/A experimental interaction detection,in vivo ComPPI,HPRD
CDK6 RBL1 22094256 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
LIN37 RBL1 25348397 N/A physical interaction ComPPI
EMD RBL1 25348397 N/A physical interaction ComPPI
SMAD4 RBL1 12150994 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MRFAP1 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RINT1 RBL1 25348397 N/A physical interaction ComPPI
C3ORF62 RBL1 25348397 N/A physical interaction ComPPI
BEGAIN RBL1 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
SP1 RBL1 14525934 25348397 27898060 7565695 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
EPHB2 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TAF1 RBL1 14525934 25348397 9242374 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
AR RBL1 25348397 N/A physical interaction ComPPI
SMAD2 RBL1 12150994 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SMAD3 RBL1 12150994 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
HDAC3 RBL1 25348397 N/A physical interaction ComPPI
CTBP1 RBL1 25348397 N/A physical interaction ComPPI
PLSCR1 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MYBL2 RBL1 12439743 12947099 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
YWHAZ RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NTRK1 RBL1 25348397 N/A physical interaction ComPPI
DGKZ RBL1 14525934 16286473 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD
IRF3 RBL1 21903422 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHB RBL1 10376528 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RBL2 RBL1 15467457 24234451 25348397 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F1 RBL1 16360038 24234451 25348397 physical association isothermal titration calorimetry,physical interaction ComPPI,IntAct
SMARCA4 RBL1 25348397 N/A physical interaction ComPPI
CDKN1C RBL1 25348397 N/A physical interaction ComPPI
MYC RBL1 14525934 25348397 8076603 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EPHA2 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TRIP6 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DYRK1B RBL1 23602568 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,bimolecular fluorescence complementation ComPPI,IntAct
MAPK6 RBL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP2CA RBL1 15467457 24234451 25348397 dephosphorylation reaction,physical association coimmunoprecipitation,phosphatase assay ComPPI,IntAct
SUV39H1 RBL1 12588981 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
E2F2 RBL1 25348397 N/A physical interaction ComPPI
E2F4 RBL1 11573202 12150994 14525934 16360038 24234451 25348397 8643455 physical association coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RBBP9 RBL1 14525934 25348397 9697699 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
USP4 RBL1 11571651 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CCNA1 RBL1 10022926 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RBBP8 RBL1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
KDM5A RBL1 14525934 25348397 7935440 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CREG1 RBL1 14525934 25348397 9710587 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
AATF RBL1 25348397 N/A physical interaction ComPPI
LIN9 RBL1 25348397 N/A physical interaction ComPPI
E2F5 RBL1 14525934 25348397 7892279 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
NR2E3 RBL1 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SNRPD3 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK2 RBL1 11884610 14525934 23455922 23602568 24234451 25348397 25852190 8230483 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
NR4A1 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HDAC2 RBL1 25348397 N/A physical interaction ComPPI
TFDP1 RBL1 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction ComPPI
TFDP2 RBL1 25348397 N/A coimmunoprecipitation,physical interaction,physical interaction ComPPI
BRF1 RBL1 10330166 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NUCB1 RBL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ID2 RBL1 11034201 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PPP2R3A RBL1 14525934 25348397 27898060 9927208 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
FOXO3 RBL1 24234451 25348397 25609649 association,physical association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
CDK4 RBL1 12006580 14525934 22094256 24234451 25348397 phosphorylation reaction experimental interaction detection,physical interaction,protein kinase assay,in vivo ComPPI,HPRD,IntAct
BRCA1 RBL1 25348397 N/A physical interaction ComPPI
CCNA2 RBL1 12439743 14525934 1532458 25348397 8230483 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NEK6 RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL1 CEBPA 10082561 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RBL1 CCNE1 14525934 25348397 8230483 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RBL1 MCM7 14525934 25348397 9566894 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
RBL1 DHX30 14525934 17255935 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RBL1 KMT5C 14525934 15750587 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
RBL1 HDAC1 14525934 25348397 9724731 N/A affinity chromatography technology,coimmunoprecipitation,experimental interaction detection,physical interaction,biochemical ComPPI,HPRD
RBL1 ARID4A 25348397 N/A physical interaction ComPPI
RBL1 E2F3 25348397 N/A physical interaction ComPPI
RBL1 LIN54 25348397 N/A physical interaction ComPPI
RBL1 TOP1 25348397 N/A physical interaction ComPPI
RBL1 AOX1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBL1 FN1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBL1 LAMB2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RBL1 MAGEA11 25348397 N/A physical interaction ComPPI
RBL1 DYRK1A 23602568 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,bimolecular fluorescence complementation ComPPI,IntAct
RBL1 TXNDC11 25348397 N/A physical interaction ComPPI
RBL1 AP5Z1 25348397 N/A physical interaction ComPPI
RBL1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
RBL1 TSC22D2 25348397 N/A physical interaction ComPPI
RBL1 MARF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RBL1 HELZ 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RBL1 TSPAN7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL1 CD320 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL1 NTHL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL1 ACTR3B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNPEP RBL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RBL1 RBL1 14525934 7935440 N/A experimental interaction detection HPRD
MAP2K1 RBL1 12006580 27898060 N/A N/A OmniPath
CDK2 RBL1 11884610 17495531 19690332 23455922 23602568 25852190 26186194 27898060 8230483 8643455 9472014 9891079 N/A N/A OmniPath
RBL1 IRF3 21903422 27898060 N/A N/A OmniPath
IRF3 RBL1 21903422 27898060 N/A N/A OmniPath
RBL1 E2F4 11573202 12150994 15838517 17671431 27898060 7958924 7958925 8643455 8657117 8832394 9144196 9501179 9724731 9858615 stimulant N/A OmniPath
CDK4 RBL1 10069453 11884610 12006580 19664994 19664995 22094256 27898060 8643455 inhibition,stimulant N/A OmniPath
PPP2CA RBL1 15467457 18927618 27898060 stimulant N/A OmniPath
CCND1 RBL1 12006580 27898060 8643455 inhibition N/A OmniPath
PPP2CB RBL1 18927618 27898060 N/A N/A OmniPath

Visualization










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