GENE:PPP3CA
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PPP3CA |
| FullNmae | protein phosphatase 3 catalytic subunit alpha |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9314 |
| EnsembleID | ENSG00000138814 |
| Uniprot | Q08209 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PPP3CA | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PPP3CA | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PPP3CA | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PPP3CA | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PPP3CA | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PPP3CA | GO:0000082,GO:0001975,GO:0004722,GO:0004722,GO:0004722,GO:0005509,GO:0005515,GO:0005516,GO:0005516,GO:0005516,GO:0005516,GO:0005516,GO:0005654,GO:0005737,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0005886,GO:0005955,GO:0005955,GO:0005955,GO:0006470,GO:0006470,GO:0006606,GO:0006816,GO:0008287,GO:0008544,GO:0009898,GO:0010628,GO:0010629,GO:0014883,GO:0014898,GO:0016018,GO:0016311,GO:0017018,GO:0019897,GO:0019899,GO:0023057,GO:0030018,GO:0030216,GO:0030335,GO:0033173,GO:0033173,GO:0033173,GO:0033192,GO:0033192,GO:0033192,GO:0033192,GO:0033555,GO:0036057,GO:0042060,GO:0042104,GO:0042110,GO:0042383,GO:0043197,GO:0043403,GO:0044877,GO:0045669,GO:0045672,GO:0045785,GO:0045807,GO:0045944,GO:0046676,GO:0046878,GO:0046983,GO:0048741,GO:0048813,GO:0050774,GO:0050804,GO:0051117,GO:0051592,GO:0060079,GO:0061006,GO:0070262,GO:0070886,GO:0071333,GO:0090193,GO:0097205,GO:0097720,GO:0098685,GO:0098978,GO:0099170,GO:0110062,GO:1903244,GO:1905205,GO:1905665,GO:1905949 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PPP3CA | hsa:5530 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04114 | Oocyte meiosis - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04218 | Cellular senescence - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04360 | Axon guidance - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04370 | VEGF signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04625 | C-type lectin receptor signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04650 | Natural killer cell mediated cytotoxicity - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04658 | Th1 and Th2 cell differentiation - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04659 | Th17 cell differentiation - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04660 | T cell receptor signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04662 | B cell receptor signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04720 | Long-term potentiation - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04724 | Glutamatergic synapse - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04728 | Dopaminergic synapse - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04921 | Oxytocin signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04922 | Glucagon signaling pathway - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa04924 | Renin secretion - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05014 | Amyotrophic lateral sclerosis - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05020 | Prion disease - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05031 | Amphetamine addiction - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05152 | Tuberculosis - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human) |
| PPP3CA | hsa:5530 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PPP3CA | FKBP8 | 12510191 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| IRF2 | PPP3CA | 21903422 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| PPP3R1 | PPP3CA | 11015619 18296442 24243840 29145629 | physical association | inferred by curator | Reactome |
| PPP3CA | NFATC2 | 10860980 11030334 12975316 17502104 29145629 8576111 8631904 8799126 9727000 | physical association | inferred by curator | Reactome |
| PPP3CA | NFATC3 | 10860980 11030334 12975316 17502104 29145629 8576111 8631904 8799126 9727000 | physical association | inferred by curator | Reactome |
| NFATC1 | PPP3CA | 10860980 11030334 12015605 12975316 16880514 16920709 17502104 19851316 29145629 8576111 8631904 8799126 9727000 | physical association | inferred by curator | Reactome |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PPP3CA | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | PPP3CA | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | PPP3CA | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | PPP3CA | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TAL1 | PPP3CA | 18971253 20028976 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PPP3CA | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | PPP3CA | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | PPP3CA | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004F4657 | PPP3CA | 19915607 | rna interference,inhibition | array technology,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS00004F4657 | PPP3CA | 19915607 25416803 | mrna cleavage,inhibition | array technology,experimental interaction detection,experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000065D58 | PPP3CA | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MYOZ2 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | MYOZ2 | 25361965 | interaction type | N/A | PTMCode2 |
| MYOZ1 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | MYOZ1 | 25361965 | interaction type | N/A | PTMCode2 |
| FKBP8 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | FKBP8 | 25361965 | interaction type | N/A | PTMCode2 |
| CRTC2 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | CRTC2 | 25361965 | interaction type | N/A | PTMCode2 |
| PPIB | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | PPIB | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3R1 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | PPP3R1 | 25361965 | interaction type | N/A | PTMCode2 |
| BAD | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | BAD | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | PPIA | 25361965 | interaction type | N/A | PTMCode2 |
| PPIA | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| BCL2 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | BCL2 | 25361965 | interaction type | N/A | PTMCode2 |
| SOD1 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | SOD1 | 25361965 | interaction type | N/A | PTMCode2 |
| AKAP5 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | AKAP5 | 25361965 | interaction type | N/A | PTMCode2 |
| DMD | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | DMD | 25361965 | interaction type | N/A | PTMCode2 |
| FKBP3 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | FKBP3 | 25361965 | interaction type | N/A | PTMCode2 |
| RCAN2 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | RCAN2 | 25361965 | interaction type | N/A | PTMCode2 |
| ATP2B4 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
| TESC | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | TESC | 25361965 | interaction type | N/A | PTMCode2 |
| CABIN1 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | CABIN1 | 25361965 | interaction type | N/A | PTMCode2 |
| CALM3 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| CALM2 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | CALM3 | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | CALM2 | 25361965 | interaction type | N/A | PTMCode2 |
| PPP3CA | CALM1 | 25361965 | interaction type | N/A | PTMCode2 |
| CALM1 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| VCP | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| FKBP1A | PPP3CA | 14525934 25348397 7543369 8524402 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| VBP1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| BAD | PPP3CA | 10195903 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| MYOZ2 | PPP3CA | 11842093 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD |
| NFATC1 | PPP3CA | 25348397 | N/A | fluorescence polarization spectroscopy,nuclear magnetic resonance,pull down,physical interaction,physical interaction,surface plasmon resonance array | ComPPI |
| CASP3 | PPP3CA | 11478781 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| GRB2 | PPP3CA | 12577067 17474147 21900206 24234451 25348397 | association,physical association | two hybrid,peptide array,pull down,physical interaction | ComPPI,IntAct |
| JUN | PPP3CA | 24234451 25348397 25609649 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RHOC | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| GSK3B | PPP3CA | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| TUBA1B | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PDIA6 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| ARFIP1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| P3H1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PSMA6 | PPP3CA | 21420386 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TRAF3 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| MYOZ1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| XPO5 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| LASP1 | PPP3CA | 22665060 24234451 25348397 | dephosphorylation reaction | phosphatase assay | ComPPI,IntAct |
| HNRNPL | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PRKCZ | PPP3CA | 12021260 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| GABRB2 | PPP3CA | 12574411 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| GABRG2 | PPP3CA | 12574411 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| MYOZ3 | PPP3CA | 11842093 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| PDE4D | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| NFATC2 | PPP3CA | 25348397 | N/A | fluorescence polarization spectroscopy,physical interaction,surface plasmon resonance array | ComPPI |
| PDHB | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| UTRN | PPP3CA | 25348397 | N/A | anti bait coimmunoprecipitation,physical interaction | ComPPI |
| MAPK7 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| RXRB | PPP3CA | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| TNPO1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| ADRB2 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| RASSF2 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PFDN5 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PPP2R2A | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PTEN | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| SYNJ1 | PPP3CA | 14525934 14704270 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| ATP2B4 | PPP3CA | 14525934 15955804 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| BCL2 | PPP3CA | 14525934 19706527 25348397 27898060 7593193 9109491 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD,OmniPath |
| NR3C1 | PPP3CA | 20195357 24234451 25348397 | physical association | display technology | ComPPI,IntAct |
| PPIA | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| FKBP8 | PPP3CA | 12510191 14525934 15757646 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| NFATC4 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| CABIN1 | PPP3CA | 11714752 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| HNRNPH1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| KCNIP3 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| TNPO3 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PPP3R1 | PPP3CA | 11439183 14525934 19896943 24234451 25348397 25416956 8524402 | association,physical association | experimental interaction detection,light scattering,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid | ComPPI,HPRD,IntAct |
| AKT1 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| MAT2B | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| RCAN1 | PPP3CA | 10861295 12063245 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| FGFR4 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | GABRA1 | 12574411 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| PPP3CA | SOD1 | 11513882 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| PPP3CA | RCAN2 | 10861295 12102656 14525934 25348397 26186194 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| PPP3CA | CRTC2 | 14525934 15454081 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| PPP3CA | C16ORF74 | 14525934 16189514 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PPP3CA | AKAP5 | 14525934 25348397 7528941 9765270 | N/A | experimental interaction detection,fluorescent resonance energy transfer,physical interaction | ComPPI,HPRD |
| PPP3CA | IRF2 | 21903422 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PPP3CA | PHLPP2 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | MRI1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | SETSIP | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | NASP | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | NRDC | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | TSN | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | MARCHF7 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | CEP76 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | TP53 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | PABIR1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | RCAN3 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | ARMT1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | PSMD9 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | LBH | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | NCAPG | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | DEFA1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | TMEM200A | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | SMPD3 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | KLRG2 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | AATK | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | RYK | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | PTK7 | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | TARDBP | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | ABL1 | 17474147 24234451 25348397 | physical association | peptide array | ComPPI,IntAct |
| PPP3CA | USP14 | 19896943 24234451 25348397 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| SIK3 | PPP3CA | 25348397 | N/A | physical interaction | ComPPI |
| PPP3CA | PPP3CA | 12574411 14525934 | N/A | experimental interaction detection | HPRD |
| PPP3CA | DNM1 | 20496096 21689596 27898060 8052858 | stimulant | N/A | OmniPath |
| PPP3CA | PRKAR2A | 27898060 9660947 | N/A | N/A | OmniPath |
| PPP3CA | VASP | 27898060 7656973 | N/A | N/A | OmniPath |
| PPP3CA | FLNA | 16442073 27898060 | inhibition | N/A | OmniPath |
| PPP3CA | PPP1R1B | 10217279 12065642 27898060 | inhibition | N/A | OmniPath |
| PPP3CA | CSNK1E | 27898060 9430669 | N/A | N/A | OmniPath |
| PPP3CA | DNM2 | 20496096 27898060 | N/A | N/A | OmniPath |
| PPP3CA | KSR2 | 19560418 27898060 | N/A | N/A | OmniPath |
| PPP3CA | BAD | 10195903 22820751 27898060 | stimulant | N/A | OmniPath |
| PPP3CA | CRYAA | 2548498 27898060 | N/A | N/A | OmniPath |
| RCAN1 | PPP3CA | 10861295 12063245 12554096 23118980 26186194 27898060 | inhibition | N/A | OmniPath |
| PPP3CA | RCAN1 | 10861295 12063245 23118980 26186194 27898060 | N/A | N/A | OmniPath |
| PPP3CA | MAPT | 15959850 16262633 27898060 9660947 | inhibition | N/A | OmniPath |
| PPP3CA | GSK3B | 19659461 27898060 | N/A | N/A | OmniPath |
| PPP3CA | HSPB1 | 27898060 7510704 | N/A | N/A | OmniPath |
| PPP3CA | FKBP8 | 12510191 15757646 27898060 | N/A | N/A | OmniPath |
| PPP3CA | JUN | 17215518 27898060 | N/A | N/A | OmniPath |
| PPP3CA | NFATC2 | 10860980 11030334 11062529 16407284 18676376 21880741 24954618 27898060 9660947 | stimulant | N/A | OmniPath |
| PPP3CA | NFATC4 | 10860980 16407284 21880741 27898060 | stimulant | N/A | OmniPath |
| IRF2 | PPP3CA | 21903422 27898060 | N/A | N/A | OmniPath |
| PPP3CA | ELK1 | 10329725 27898060 | N/A | N/A | OmniPath |
| PPP3CA | NFATC1 | 10860980 14722106 15276472 16407284 17502104 19285944 21880741 23015147 23468591 24954618 27898060 | stimulant | N/A | OmniPath |
| PPP3CA | PPP1R1A | 11278334 27898060 | inhibition | N/A | OmniPath |
| PPP3CA | NEFH | 20031277 27898060 | N/A | N/A | OmniPath |
| PPP3CA | CANX | 20700529 27898060 | N/A | N/A | OmniPath |
| PPP3CA | DNM1L | 17721437 18838687 27898060 | stimulant | N/A | OmniPath |
| PPP3CA | SSH1 | 15671020 27898060 | stimulant | N/A | OmniPath |
| PPP3CA | NFATC3 | 10860980 11509611 16407284 21880741 27898060 | stimulant | N/A | OmniPath |
| PPP3CA | GAD1 | 15147202 27898060 7896780 | N/A | N/A | OmniPath |
| PPP3CA | GAD2 | 15147202 27898060 | N/A | N/A | OmniPath |
| PPP3CA | SLC10A1 | 12065290 27898060 | N/A | N/A | OmniPath |
