GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
PRKX |
FullNmae |
protein kinase cAMP-dependent X-linked catalytic subunit |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:9441 |
EnsembleID |
ENSG00000183943 |
Uniprot |
P51817 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
PRKX |
apoptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
PRKX |
GO:0001525,GO:0001935,GO:0004691,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0007155,GO:0018105,GO:0030099,GO:0030155,GO:0030334,GO:0031589,GO:0043542,GO:0046777,GO:0060562,GO:0060993,GO:0106310,GO:2000696 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
PRKX |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
ETS1 |
PRKX |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
PRKX |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
PRDM14 |
PRKX |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
SMARCA4 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F4 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
SPI1 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
TRIM28 |
PRKX |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00000ED600 |
PRKX |
20215506
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000085F64 |
PRKX |
19536157
23313552
23824327
24906430
25416803
27418678
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000076B539 |
PRKX |
19536157
22927820
23313552
23824327
24906430
25416803
27418678
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000015B295 |
PRKX |
23313552
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000016FD1B |
PRKX |
23313552
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004DA9DB |
PRKX |
22927820
23313552
23824327
25416803
28735896
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001F8FF2 |
PRKX |
19536157
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000018D2BE |
PRKX |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002FB065 |
PRKX |
23824327
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00001EFEC1 |
PRKX |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000285DCB |
PRKX |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000101787 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000003ABC4 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00004AF715 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000209F04 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000EE7F0 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000030F801 |
PRKX |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000F4AC3 |
PRKX |
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000321A1A |
PRKX |
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PRKX |
SMAD6 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
PRKX |
PKD1 |
22135298
|
phosphorylation |
N/A |
PhosphoSite |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
GPKOW |
PRKX |
16491121
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,two hybrid |
ComPPI,IntAct |
PRKAR2B |
PRKX |
25348397
|
N/A |
physical interaction |
ComPPI |
HSP90AB1 |
PRKX |
22939624
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping |
ComPPI,IntAct |
PRKAR1A |
PRKX |
10026146
14525934
16491121
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo |
ComPPI,HPRD,IntAct |
HSP90AA1 |
PRKX |
25348397
|
N/A |
physical interaction |
ComPPI |
PKIA |
PRKX |
10026146
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
PRKAR2A |
PRKX |
10026146
14525934
25348397
|
N/A |
experimental interaction detection,in vitro |
ComPPI,HPRD |
PRKX |
NEDD4 |
25348397
|
N/A |
physical interaction |
ComPPI |
PRKX |
HSP90AA2P |
25348397
|
N/A |
physical interaction |
ComPPI |
PRKX |
XPO1 |
25348397
|
N/A |
physical interaction |
ComPPI |
PRKX |
HNRNPL |
25348397
|
N/A |
physical interaction |
ComPPI |
PRKX |
SMAD6 |
16491121
24234451
25348397
|
phosphorylation reaction,physical association |
anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,protein kinase assay |
ComPPI,IntAct |
NEDD4L |
PRKX |
25348397
|
N/A |
physical interaction |
ComPPI |
PRKX |
PKD1 |
17980165
27898060
|
stimulant |
N/A |
OmniPath |
PRKX |
MAP3K7 |
25028512
27898060
|
N/A |
N/A |
OmniPath |
PRKX |
SMAD6 |
16491121
27898060
|
N/A |
N/A |
OmniPath |
Visualization