Gene Information gene info

GENE:PRKX

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRKX
FullNmae protein kinase cAMP-dependent X-linked catalytic subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9441
EnsembleID ENSG00000183943
Uniprot P51817

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRKX apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRKX GO:0001525,GO:0001935,GO:0004691,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0007155,GO:0018105,GO:0030099,GO:0030155,GO:0030334,GO:0031589,GO:0043542,GO:0046777,GO:0060562,GO:0060993,GO:0106310,GO:2000696

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRKX EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRKX MAP3K7 23180781 25028512 physical association anti tag coimmunoprecipitation InnateDB
PRKX PREX1 16301320 23109003 inhibition N/A SignaLink
CAMP PRKX 15539636 16460834 23109003 7935349 chemical activation reaction N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR PRKX 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PRKX 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PRKX 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PRKX 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRKX 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 PRKX 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000085F64 PRKX 19536157 23313552 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000076B539 PRKX 19536157 22927820 23313552 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000015B295 PRKX 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1B PRKX 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB PRKX 22927820 23313552 23824327 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00001F8FF2 PRKX 19536157 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000018D2BE PRKX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FB065 PRKX 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 PRKX 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000285DCB PRKX 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 PRKX 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 PRKX 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000321A1A PRKX 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKX SMAD6 22135298 phosphorylation N/A PhosphoSite
PRKX PKD1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GPKOW PRKX 16491121 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
PRKAR2B PRKX 25348397 N/A physical interaction ComPPI
HSP90AB1 PRKX 22939624 24234451 25348397 physical association anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping ComPPI,IntAct
PRKAR1A PRKX 10026146 14525934 16491121 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
HSP90AA1 PRKX 25348397 N/A physical interaction ComPPI
PKIA PRKX 10026146 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKAR2A PRKX 10026146 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKX NEDD4 25348397 N/A physical interaction ComPPI
PRKX HSP90AA2P 25348397 N/A physical interaction ComPPI
PRKX XPO1 25348397 N/A physical interaction ComPPI
PRKX HNRNPL 25348397 N/A physical interaction ComPPI
PRKX SMAD6 16491121 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,protein kinase assay ComPPI,IntAct
NEDD4L PRKX 25348397 N/A physical interaction ComPPI
PRKX PKD1 17980165 27898060 stimulant N/A OmniPath
PRKX MAP3K7 25028512 27898060 N/A N/A OmniPath
PRKX SMAD6 16491121 27898060 N/A N/A OmniPath

Visualization