Gene Information gene info

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GENE：FGF6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FGF6
FullNmae fibroblast growth factor 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3684
EnsembleID ENSG00000111241
Uniprot P10767

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FGF6 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FGF6 GO:0001502,GO:0001525,GO:0001934,GO:0005104,GO:0005515,GO:0005576,GO:0005615,GO:0005737,GO:0008083,GO:0008284,GO:0008284,GO:0008543,GO:0008543,GO:0009887,GO:0010628,GO:0030154,GO:0030334,GO:0042383,GO:0045445,GO:0051781

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FGF6 hsa:2251 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
FGF6 hsa:2251 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
FGF6 hsa:2251 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
FGF6 hsa:2251 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
FGF6 hsa:2251 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
FGF6 hsa:2251 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
FGF6 hsa:2251 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FGF6 hsa:2251 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
FGF6 hsa:2251 path:hsa05218 Melanoma - Homo sapiens (human)
FGF6 hsa:2251 path:hsa05224 Breast cancer - Homo sapiens (human)
FGF6 hsa:2251 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FGF6 FGFR2 23331499 8663044 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
YBX1 FGF6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 FGF6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
FGFR2 FGF6 25348397 N/A physical interaction,physical interaction,biochemical,in vitro ComPPI
FGFR3 FGF6 14525934 25348397 8663044 N/A experimental interaction detection,in vitro ComPPI,HPRD
FGFR1 FGF6 25348397 N/A physical interaction,in vitro ComPPI
FGFR4 FGF6 1385111 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FGF6 FGFR2 27898060 8663044 stimulant N/A OmniPath
FGF6 FGFR4 1385111 27898060 stimulant N/A OmniPath

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