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GENE：GDF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GDF7
FullNmae growth differentiation factor 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4222
EnsembleID ENSG00000143869
Uniprot Q7Z4P5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GDF7 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GDF7 GO:0005125,GO:0005515,GO:0005615,GO:0007411,GO:0008083,GO:0010628,GO:0021509,GO:0021527,GO:0022612,GO:0030509,GO:0030509,GO:0030855,GO:0030901,GO:0032924,GO:0042802,GO:0045165,GO:0045666,GO:0045893,GO:0048608,GO:0048754,GO:0048853,GO:0060391,GO:0060571,GO:2001051

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GDF7 hsa:151449 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
GDF7 hsa:151449 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)
GDF7 hsa:151449 path:hsa04360 Axon guidance - Homo sapiens (human)
GDF7 hsa:151449 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRDM14 GDF7 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA GDF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GDF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GDF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GDF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GDF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F4AC3 GDF7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D8730 GDF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000306C70 GDF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 GDF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 GDF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 GDF7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD80B GDF7 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 GDF7 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GDF7 BMP7 12741987 14525934 27898060 N/A experimental interaction detection HPRD,OmniPath

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