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GENE：PRKAR2B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRKAR2B
FullNmae protein kinase cAMP-dependent type II regulatory subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9392
EnsembleID ENSG00000005249
Uniprot P31323

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRKAR2B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PRKAR2B apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRKAR2B GO:0004862,GO:0004862,GO:0005515,GO:0005737,GO:0005813,GO:0005829,GO:0005829,GO:0005886,GO:0005952,GO:0006631,GO:0007612,GO:0008603,GO:0019904,GO:0030552,GO:0031625,GO:0034236,GO:0034236,GO:0035556,GO:0043025,GO:0043197,GO:0043198,GO:0048471,GO:0050804,GO:0070062,GO:0097332,GO:0097546,GO:0098978,GO:2000480,GO:2000480

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRKAR2B hsa:5577 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
USO1 PRKAR2B 22792062 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 PRKAR2B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 PRKAR2B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 PRKAR2B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PRKAR2B 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PRKAR2B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000272039 PRKAR2B 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA PRKAR2B 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
GNAI3 PRKAR2B 25348397 N/A physical interaction ComPPI
PDE4DIP PRKAR2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPRE1 PRKAR2B 25348397 N/A physical interaction ComPPI
TOMM22 PRKAR2B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRKAR2B KIF5B 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR2B TAF12 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR2B RYR2 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP5 11557526 14525934 25348397 26186194 27898060 8509414 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PRKAR2B CFAP91 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP11 10864471 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PRKAR2B USO1 25348397 N/A physical interaction ComPPI
PRKAR2B GCH1 25348397 N/A physical interaction ComPPI
PRKAR2B SOX2 25348397 N/A physical interaction ComPPI
PRKAR2B PRKACA 17148597 23455922 24234451 24605759 25348397 26496610 27107012 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,protein kinase assay,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
PRKAR2B PRKACB 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PRKAR2B AKAP7 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP7 25348397 N/A physical interaction ComPPI
PRKAR2B SPA17 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP1 10764601 11483602 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PRKAR2B PRKAR2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B AKAP9 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP13 25348397 N/A physical interaction ComPPI
PRKAR2B CDK5RAP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B PRKACG 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP2 25348397 N/A physical interaction ComPPI
PRKAR2B MAP2 25348397 N/A physical interaction ComPPI
PRKAR2B ZG16B 25348397 N/A physical interaction ComPPI
PRKAR2B AMY1C 25348397 N/A physical interaction ComPPI
PRKAR2B PRKX 25348397 N/A physical interaction ComPPI
PRKAR2B CRYBG3 25348397 N/A physical interaction ComPPI
PRKAR2B PRKAR1B 25348397 N/A physical interaction ComPPI
PRKAR2B NAA25 25348397 N/A physical interaction ComPPI
PRKAR2B VAPB 25348397 N/A physical interaction ComPPI
PRKAR2B AKAP14 12475942 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,HPRD,IntAct
PRKAR2B HERC2 25348397 N/A physical interaction ComPPI
PRKAR2B HERC2P3 25348397 N/A physical interaction ComPPI
PRKAR2B CSNK1D 25348397 N/A physical interaction ComPPI
PRKAR2B DYNC1I2 25348397 N/A physical interaction ComPPI
PRKAR2B PCM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B SURF4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B VAV2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B OFD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B CEP170 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B CEP131 25348397 N/A physical interaction ComPPI
PRKAR2B CEP68 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B HBP1 25348397 N/A physical interaction ComPPI
PRKAR2B BABAM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B COPS7A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B CEP72 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B MIB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B CCDC77 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B SSX2 25348397 N/A physical interaction ComPPI
PRKAR2B ALX3 25348397 N/A physical interaction ComPPI
PRKAR2B ROPN1 25348397 N/A physical interaction ComPPI
PRKAR2B IQCN 25348397 N/A physical interaction ComPPI
PRKAR2B GJB7 25348397 N/A physical interaction ComPPI
PRKAR2B CSNK1E 25348397 N/A physical interaction ComPPI
PRKAR2B PRKAR1A 25348397 N/A physical interaction ComPPI
PRKAR2B NUFIP1 25348397 N/A physical interaction ComPPI
PRKAR2B HAX1 25348397 N/A physical interaction ComPPI
PRKAR2B TRIM25 25348397 N/A physical interaction ComPPI
PRKAR2B TNFRSF1A 18625701 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
PRKAR2B ARFGEF2 18625701 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,confocal microscopy ComPPI,IntAct
PRKAR2B C2ORF88 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR2B ECM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR2B TOMM20 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ZNF707 PRKAR2B 25348397 N/A physical interaction ComPPI
PRKAR2B PRKAR2B 14525934 7479855 N/A experimental interaction detection HPRD
AKAP4 PRKAR2B 14525934 9852104 N/A experimental interaction detection,two hybrid HPRD
AKAP10 PRKAR2B 14525934 9326583 N/A experimental interaction detection HPRD
NBEA PRKAR2B 11102458 14525934 N/A experimental interaction detection HPRD
PRKACA PRKAR2B 15187164 17148597 23455922 26186194 26496610 27898060 stimulant N/A OmniPath
ATM PRKAR2B 27898060 7479855 N/A N/A OmniPath
PRKAR2B LASP1 12432067 12571245 17287340 18077418 18088087 18212344 18669648 20068231 20166139 27898060 N/A N/A OmniPath

Visualization










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