GENE:PXDN
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PXDN |
| FullNmae | peroxidasin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14966 |
| EnsembleID | ENSG00000130508 |
| Uniprot | Q92626 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PXDN | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PXDN | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PXDN | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PXDN | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PXDN | GO:0001525,GO:0001654,GO:0001960,GO:0004601,GO:0004601,GO:0005152,GO:0005201,GO:0005201,GO:0005576,GO:0005604,GO:0005615,GO:0005615,GO:0005783,GO:0006955,GO:0006979,GO:0007155,GO:0009986,GO:0016684,GO:0016684,GO:0020037,GO:0030198,GO:0030199,GO:0031012,GO:0042744,GO:0043237,GO:0046872,GO:0051260,GO:0062023,GO:0062023,GO:0070062,GO:0070207,GO:0070207,GO:0070831,GO:0070831,GO:0071711,GO:0098869,GO:0140825 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | PXDN | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | PXDN | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA3 | PXDN | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | PXDN | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA2 | PXDN | 10438731 18971253 9558404 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | PXDN | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPE | PXDN | 12202480 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| GATA1 | PXDN | 10438731 12202480 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | PXDN | 12202480 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | PXDN | N/A | rna interference,inhibition | experimental interaction detection | miRSponge |
| URS0000076995 | PXDN | 20566844 | rna interference,inhibition | western blot,miRNA interference luciferase reporter assay | miRSponge |
| URS0000324096 | PXDN | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection,experimental interaction detection,experimental interaction detection | TarBase |
| URS0000076995 | PXDN | 20566844 25416803 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
| URS00000B59A2 | PXDN | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000122ED0 | PXDN | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000005481D | PXDN | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000083D87 | PXDN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | PXDN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | PXDN | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | PXDN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000472A9B | PXDN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | PXDN | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | PXDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000224AEA | PXDN | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NTRK1 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| PLAUR | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| CFTR | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| SPTAN1 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| ADCYAP1 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| HECW2 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| NELL2 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| HAUS1 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| DEFA1 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| FBXO6 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| CD96 | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| PTPRK | PXDN | 25348397 | N/A | physical interaction | ComPPI |
| PXDN | CNPY3 | 25348397 | N/A | physical interaction | ComPPI |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B0AAA | PXDN | 27087310 | direct interaction,inhibition | N/A | NPInter |
