Gene Information gene info

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GENE：USP25

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol USP25
FullNmae ubiquitin specific peptidase 25
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12624
EnsembleID ENSG00000155313
Uniprot Q9UHP3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
USP25 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
USP25 GO:0004843,GO:0004843,GO:0004843,GO:0005515,GO:0005634,GO:0005783,GO:0005829,GO:0005829,GO:0005829,GO:0006508,GO:0008233,GO:0016579,GO:0016579,GO:0019783,GO:0031625,GO:0031647,GO:0032183,GO:0032183,GO:0036211,GO:0043130,GO:0051117,GO:0070536,GO:0071108,GO:1904293

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
USP25 hsa:29761 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR USP25 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 USP25 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 USP25 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 USP25 20554955 23395819 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
PRDM14 USP25 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 USP25 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001B341F USP25 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000031602A USP25 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171525 USP25 23807165 24997798 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00004719AB USP25 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 USP25 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F USP25 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 USP25 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00004BCD9C USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 USP25 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
USP25 FLNC 25361965 interaction type N/A PTMCode2
FLNC USP25 25361965 interaction type N/A PTMCode2
KCTD10 USP25 25361965 interaction type N/A PTMCode2
USP25 KCTD10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBE2I USP25 25348397 N/A physical interaction ComPPI
MAGEB4 USP25 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT4 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ANXA1 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SKIL USP25 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
TRAF6 USP25 23042150 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDC37L1 USP25 25348397 N/A physical interaction ComPPI
KCTD13 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
APPBP2 USP25 25348397 N/A physical interaction ComPPI
ZNF426 USP25 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SYK USP25 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO1 USP25 25348397 N/A physical interaction ComPPI
FLNC USP25 25348397 N/A physical interaction ComPPI
CUL3 USP25 25348397 N/A physical interaction ComPPI
GAPDH USP25 25348397 N/A physical interaction ComPPI
UBB USP25 25348397 N/A physical interaction ComPPI
UBC USP25 25348397 N/A physical interaction ComPPI
HSP90B1 USP25 25348397 N/A physical interaction ComPPI
TNFAIP1 USP25 25348397 N/A physical interaction ComPPI
GDI1 USP25 25348397 N/A physical interaction ComPPI
RAD23A USP25 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO2 USP25 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO3 USP25 25348397 N/A physical interaction ComPPI
NEDD8 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL2 USP25 25348397 N/A physical interaction ComPPI
SON USP25 25348397 N/A physical interaction ComPPI
TRAF5 USP25 23042150 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PIP USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WRNIP1 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD23B USP25 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MYO6 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNKS USP25 25348397 N/A physical interaction ComPPI
TNKS2 USP25 22153077 24234451 25348397 N/A fluorescence polarization spectroscopy,physical interaction ComPPI,IntAct
SENP2 USP25 25348397 N/A physical interaction ComPPI
FEM1B USP25 25348397 N/A physical interaction ComPPI
MT2A USP25 25348397 N/A physical interaction ComPPI
UGGT1 USP25 25348397 N/A physical interaction ComPPI
MYBPC1 USP25 25348397 N/A physical interaction ComPPI
ACTA1 USP25 25348397 N/A physical interaction ComPPI
TMEM43 USP25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LYZ USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP28 USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZG16B USP25 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP25 KLHL9 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP25 KCTD10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP25 BTBD9 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP25 KLHL13 25348397 N/A physical interaction ComPPI
USP25 RELCH 25348397 N/A physical interaction ComPPI
USP25 SENP1 25348397 N/A physical interaction ComPPI
USP25 CROT 25348397 N/A physical interaction ComPPI
USP25 APP 25348397 N/A physical interaction ComPPI
USP25 HRNR 25348397 N/A physical interaction ComPPI
USP25 KLHDC10 25348397 N/A physical interaction ComPPI
USP25 PUS10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LRFN4 USP25 25348397 N/A physical interaction ComPPI
TRAF2 USP25 24234451 30561431 association virotrap IntAct
VRK2 USP25 25755282 27898060 N/A N/A OmniPath

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