GENE：AMHR2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AMHR2 |
| FullNmae | anti-Mullerian hormone receptor type 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:465 |
| EnsembleID | ENSG00000135409 |
| Uniprot | Q16671 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AMHR2 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AMHR2 | GO:0001568,GO:0001880,GO:0005024,GO:0005026,GO:0005515,GO:0005524,GO:0005886,GO:0005886,GO:0005886,GO:0006468,GO:0007179,GO:0007548,GO:0007548,GO:0008584,GO:0008585,GO:0016310,GO:0030509,GO:0042562,GO:0042803,GO:0043235,GO:0046872,GO:0071363,GO:1990262,GO:1990262,GO:1990272,GO:1990272 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AMHR2 | hsa:269 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| AMHR2 | hsa:269 | path:hsa04350 | TGF-beta signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AMH | AMHR2 | 16446785 18988627 23331499 8889695 | stimulation | N/A | SignaLink,SignaLink |
| BMP6 | AMHR2 | 16446785 23331499 | stimulation | N/A | SignaLink |
| AMHR2 | ACVR1 | 16446785 23331499 | stimulation | N/A | SignaLink |
| AMHR2 | BMPR1B | 16446785 23331499 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | AMHR2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | AMHR2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AMHR2 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | AMHR2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | AMHR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AMHR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AMHR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AMHR2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| APC | AMHR2 | 12724325 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HSP90AB1 | AMHR2 | 22939624 24234451 25348397 | physical association | anti tag coimmunoprecipitation,luminescence based mammalian interactome mapping | ComPPI,IntAct |
| HSP90AA1 | AMHR2 | 24234451 25036637 25348397 | physical association | physical interaction,luminescence based mammalian interactome mapping | ComPPI,IntAct |
| AMHR2 | AMH | 14525934 25348397 8889695 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| AMHR2 | BMPR1B | 11420127 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| AMHR2 | PTEN | 25348397 | N/A | physical interaction | ComPPI |
| AMHR2 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
| AMHR2 | CDC37 | 24234451 25036637 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| AMHR2 | MAL | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AMHR2 | TGFBR1 | 11420127 14525934 | N/A | experimental interaction detection | HPRD |
| AMHR2 | BMPR1B | 11420127 14746809 27898060 | stimulant | N/A | OmniPath |
| AMHR2 | ACVR1 | 14746809 27898060 | stimulant | N/A | OmniPath |
| AMH | AMHR2 | 27898060 7997230 8119126 8889695 | stimulant | N/A | OmniPath |