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GENE：LMNB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LMNB2
FullNmae lamin B2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6638
EnsembleID ENSG00000176619
Uniprot Q03252

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LMNB2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LMNB2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LMNB2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
LMNB2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LMNB2 GO:0003674,GO:0005200,GO:0005515,GO:0005635,GO:0005652,GO:0005882,GO:0006998,GO:0007010,GO:0007097,GO:0008150,GO:0031507,GO:0031965,GO:0042802,GO:0051664,GO:0090435

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
LMNB2 hsa:84823 path:hsa04210 Apoptosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 LMNB2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 LMNB2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR LMNB2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 LMNB2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ESR1 LMNB2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 LMNB2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 LMNB2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LMNB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC LMNB2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 LMNB2 19074876 rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000B59A2 LMNB2 19074876 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,experimental interaction detection,western blot,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000065D58 LMNB2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS00003380CC LMNB2 17612493 20371350 21572407 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS00000F31F4 LMNB2 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00001B341F LMNB2 20371350 22473208 25416803 26701625 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000035CC3E LMNB2 20371350 23622248 25416803 mrna cleavage,inhibition nucleotide sequence identification,clash TarBase
URS000033EBB8 LMNB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D LMNB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 LMNB2 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS00000AA464 LMNB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004719AB LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000028C188 LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E92A8 LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 LMNB2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004A6E26 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008C563 LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC LMNB2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF LMNB2 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000077AED LMNB2 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F4657 LMNB2 20371350 21572407 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003A5E54 LMNB2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 LMNB2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000048B5E9 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E5E03 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000098B3B LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000D0874 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000239117 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000026A1D LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015CE89 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000002103A LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000008A99 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C770D LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000083D87 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000184017 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001E96DA LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000166778 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000001EB3 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000192A75 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000049704B LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003B6B84 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000254A6 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000148B91 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004900F1 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000451A1 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000328C0D LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000025307A LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B1B47 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000043B1D LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000018E6CD LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000480E22 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000221168 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075BC91 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E5ECC LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005D35D9 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000010BD8D LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005F9738 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002ED720 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002F5FEE LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000011A030 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122F23 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023F008 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006A1CB LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002578DA LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E226A LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000913AC LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006372A LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001496AE LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000054A671 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000055929F LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000585553 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075CC78 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D814 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000EC1BE LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001012BC LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000246356 LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA LMNB2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 LMNB2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MFAP1 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA2 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WASHC3 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R13B LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CA8 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VCP LMNB2 25348397 N/A physical interaction ComPPI
LMNA LMNB2 24234451 25348397 29568061 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FOXB1 LMNB2 25348397 N/A physical interaction ComPPI
BMI1 LMNB2 25348397 N/A physical interaction ComPPI
KEAP1 LMNB2 25348397 N/A physical interaction ComPPI
GPRASP2 LMNB2 25348397 N/A physical interaction ComPPI
MAPK1 LMNB2 25348397 N/A physical interaction ComPPI
PRKCD LMNB2 25348397 N/A in vitro ComPPI
MAPK3 LMNB2 25348397 N/A physical interaction ComPPI
JUN LMNB2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
TUBG1 LMNB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 LMNB2 25348397 N/A physical interaction ComPPI
CFTR LMNB2 25348397 N/A physical interaction ComPPI
VDAC1 LMNB2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
TMPO LMNB2 25348397 N/A physical interaction ComPPI
ABCE1 LMNB2 25348397 N/A physical interaction ComPPI
SOX4 LMNB2 25348397 N/A physical interaction ComPPI
YY1 LMNB2 23531880 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LMNB1 LMNB2 24234451 25348397 26524528 30021884 association,physical association anti bait coimmunoprecipitation,two hybrid,cross-linking study,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BANF1 LMNB2 25348397 N/A physical interaction ComPPI
RNF2 LMNB2 25348397 N/A physical interaction ComPPI
EED LMNB2 25348397 N/A physical interaction ComPPI
CUL7 LMNB2 25348397 N/A physical interaction ComPPI
SVIL LMNB2 25348397 N/A two hybrid,physical interaction ComPPI
CDC37 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RFXANK LMNB2 25348397 N/A physical interaction ComPPI
ANKRA2 LMNB2 25348397 N/A physical interaction ComPPI
TFIP11 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM25 LMNB2 25348397 N/A physical interaction ComPPI
ELAVL1 LMNB2 25348397 N/A physical interaction ComPPI
DYNLT1 LMNB2 25348397 N/A physical interaction ComPPI
TRIM27 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SOD1 LMNB2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
PAN2 LMNB2 25348397 N/A physical interaction ComPPI
LZTS1 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SUZ12 LMNB2 25348397 N/A physical interaction ComPPI
CCDC88B LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THAP1 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCM7 LMNB2 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
DLST LMNB2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
USP2 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CCDC120 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMOTL2 LMNB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SIRT7 LMNB2 25348397 N/A physical interaction ComPPI
LEO1 LMNB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FNTB LMNB2 25348397 N/A physical interaction ComPPI
LMNB2 TMPO 25348397 N/A physical interaction ComPPI
LMNB2 OBSL1 25348397 N/A physical interaction ComPPI
LMNB2 CCDC8 25348397 N/A physical interaction ComPPI
LMNB2 TRNAU1AP 25348397 N/A physical interaction ComPPI
LMNB2 HERC2 25348397 N/A physical interaction ComPPI
LMNB2 HERC2P3 25348397 N/A physical interaction ComPPI
LMNB2 KDM3B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMNB2 FOXA3 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LMNB2 GAN 25348397 N/A physical interaction ComPPI
LMNB2 FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
LMNB2 HYPK 25348397 N/A physical interaction ComPPI
LMNB2 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LMNB2 SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
LMNB2 LRRK2 23075850 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
LMNB2 PHC3 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
LMNB2 OVOL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNB2 POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNB2 TSGA10IP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNB2 EFHC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNB2 FH 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNB2 LMNB2 24234451 physical association two hybrid array,two hybrid prey pooling approach IntAct
MKI67 LMNB2 24234451 26949251 association anti tag coimmunoprecipitation IntAct
ZBTB3 LMNB2 24234451 30021884 physical association cross-linking study IntAct
LMNB2 GPR101 24234451 30021884 physical association cross-linking study IntAct
LMNB2 SFI1 24234451 30021884 physical association cross-linking study IntAct
CDK2 LMNB2 20580708 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B9383 LMNB2 27087310 direct interaction,inhibition N/A NPInter

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