GENE:ATP2B4
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | ATP2B4 |
FullNmae | ATPase plasma membrane Ca2+ transporting 4 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:817 |
EnsembleID | ENSG00000058668 |
Uniprot | P23634 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
ATP2B4 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
ATP2B4 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
ATP2B4 | GO:0003407,GO:0005388,GO:0005388,GO:0005388,GO:0005515,GO:0005516,GO:0005524,GO:0005886,GO:0005886,GO:0005886,GO:0005901,GO:0006357,GO:0006874,GO:0006874,GO:0006874,GO:0007283,GO:0010629,GO:0010751,GO:0014832,GO:0015085,GO:0016020,GO:0016020,GO:0016323,GO:0016525,GO:0016887,GO:0017080,GO:0019901,GO:0021766,GO:0030018,GO:0030165,GO:0030315,GO:0030317,GO:0030346,GO:0030346,GO:0030346,GO:0032991,GO:0033138,GO:0034220,GO:0036126,GO:0036487,GO:0043231,GO:0043537,GO:0045019,GO:0045121,GO:0046872,GO:0048787,GO:0050998,GO:0051001,GO:0051480,GO:0051599,GO:0070588,GO:0070885,GO:0070885,GO:0071872,GO:0097110,GO:0097228,GO:0097553,GO:0098703,GO:0098736,GO:0098978,GO:0140199,GO:0150104,GO:1900082,GO:1901660,GO:1902083,GO:1902305,GO:1902548,GO:1902806,GO:1903078,GO:1903243,GO:1903249,GO:1903779,GO:1905145,GO:2000481 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
ATP2B4 | hsa:493 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04024 | cAMP signaling pathway - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04261 | Adrenergic signaling in cardiomyocytes - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04925 | Aldosterone synthesis and secretion - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04961 | Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04970 | Salivary secretion - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04972 | Pancreatic secretion - Homo sapiens (human) |
ATP2B4 | hsa:493 | path:hsa04978 | Mineral absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
ERBIN | ATP2B4 | 15123239 23180781 | physical association | peptide array | InnateDB |
NOS3 | ATP2B4 | 20211863 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
ADRB2 | ATP2B4 | 23180781 23798571 | physical association | anti tag coimmunoprecipitation | InnateDB |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | ATP2B4 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | ATP2B4 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA1 | ATP2B4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | ATP2B4 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
FOXP3 | ATP2B4 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | ATP2B4 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TRIM28 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TAL1 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | ATP2B4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | ATP2B4 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000009262D | ATP2B4 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000BE495 | ATP2B4 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00002FC5B0 | ATP2B4 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | ATP2B4 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000427B68 | ATP2B4 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
URS00004719AB | ATP2B4 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
URS00001BCAC5 | ATP2B4 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000047A8F | ATP2B4 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000E7139 | ATP2B4 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000101787 | ATP2B4 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000035CC3E | ATP2B4 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
RASSF1 | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | RASSF1 | 25361965 | interaction type | N/A | PTMCode2 |
DLG4 | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | DLG4 | 25361965 | interaction type | N/A | PTMCode2 |
YWHAE | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | YWHAE | 25361965 | interaction type | N/A | PTMCode2 |
CD22 | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | CD22 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | DLG3 | 25361965 | interaction type | N/A | PTMCode2 |
DLG3 | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | CASK | 25361965 | interaction type | N/A | PTMCode2 |
CASK | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
ATP2B4 | PPP3CA | 25361965 | interaction type | N/A | PTMCode2 |
PPP3CA | ATP2B4 | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
LGALS3 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
AGTR1 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
CALM1 | ATP2B4 | 25348397 | N/A | x-ray crystallography,physical interaction | ComPPI |
NMUR2 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
LGALS9C | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
DLG4 | ATP2B4 | 11274188 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
ERBIN | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
SRC | ATP2B4 | 12540962 14525934 25348397 9182531 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
CANX | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
CDH1 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
KCNA5 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
DLG2 | ATP2B4 | 11274188 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
LILRB4 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
CFTR | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
CD47 | ATP2B4 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
CASK | ATP2B4 | 12511555 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
AQP1 | ATP2B4 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
DLG1 | ATP2B4 | 11274188 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
ATP1A1 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
ADRB2 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
EGFR | ATP2B4 | 24189400 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
YWHAE | ATP2B4 | 16126729 24234451 25348397 | association | coimmunoprecipitation | ComPPI,IntAct |
CDK7 | ATP2B4 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
RASSF1 | ATP2B4 | 14525934 15145946 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
DLG3 | ATP2B4 | 11274188 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
GPC1 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
LGALS8 | ATP2B4 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | PPP3CA | 14525934 15955804 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
ATP2B4 | CD22 | 14525934 15133509 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
ATP2B4 | NOS1 | 11591728 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD,OmniPath |
ATP2B4 | BSG | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | TAS2R7 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | EDA2R | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | HSD17B6 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | LGALS9 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | SLC39A4 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | LYPD3 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | DLK1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | WBP1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | PTGER3 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | TMEM52B | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | ATP9A | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | HM13 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | ATP5PF | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | CLGN | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | TMEM17 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
ATP2B4 | CTDSPL | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | ATP2B2 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | RXYLT1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | LPAR1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | FPR2 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | IPPK | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | FAM174A | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | C3AR1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | CYP2B6 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | PCDHGB1 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | APLNR | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | HTR3A | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | VAC14 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
ATP2B4 | CALCA | 17689535 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
ATP2B4 | STIM1 | 22246182 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct,OmniPath |
ATP2B4 | SLC4A1 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | FLOT1 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | FLOT2 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | SLC2A1 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | SLC29A1 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | STOM | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
ATP2B4 | SLC14A1 | 23219802 24234451 25348397 | association | cross-linking study | ComPPI,IntAct |
COX5B | ATP2B4 | 24234451 30021884 | physical association | cross-linking study | IntAct |
SRC | ATP2B4 | 12540962 27898060 9182531 | N/A | N/A | OmniPath |
PTK2 | ATP2B4 | 12540962 25847233 27898060 | N/A | N/A | OmniPath |
SYK | ATP2B4 | 12540962 27898060 9182531 | N/A | N/A | OmniPath |
DLG1 | ATP2B4 | 11274188 27898060 | N/A | N/A | OmniPath |
ERBIN | ATP2B4 | 15123239 27898060 | N/A | N/A | OmniPath |
DLG4 | ATP2B4 | 11274188 27898060 | N/A | N/A | OmniPath |
DLG3 | ATP2B4 | 11274188 27898060 | N/A | N/A | OmniPath |
DLG2 | ATP2B4 | 11274188 17384233 27898060 | N/A | N/A | OmniPath |