GENE：PLA2G3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PLA2G3 |
| FullNmae | phospholipase A2 group III |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17934 |
| EnsembleID | ENSG00000100078 |
| Uniprot | Q9NZ20 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PLA2G3 | lysosomal_cd | 36341760 | 220 lysosome-dependent cell death genes. | retulator signature |
| PLA2G3 | lysosomal_cd | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| PLA2G3 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PLA2G3 | GO:0001675,GO:0002532,GO:0005576,GO:0005615,GO:0005814,GO:0005886,GO:0006644,GO:0006658,GO:0007288,GO:0010629,GO:0010744,GO:0010976,GO:0019372,GO:0031394,GO:0032308,GO:0034374,GO:0034375,GO:0042116,GO:0043303,GO:0043524,GO:0046337,GO:0046470,GO:0046471,GO:0046473,GO:0046488,GO:0046872,GO:0047498,GO:0048469,GO:0050482,GO:0055037,GO:0060271,GO:0060376,GO:1900017,GO:1900222,GO:1903595,GO:2001135 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PLA2G3 | hsa:50487 | path:hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa00565 | Ether lipid metabolism - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa00590 | Arachidonic acid metabolism - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa00591 | Linoleic acid metabolism - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa00592 | alpha-Linolenic acid metabolism - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa04014 | Ras signaling pathway - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa04270 | Vascular smooth muscle contraction - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa04972 | Pancreatic secretion - Homo sapiens (human) |
| PLA2G3 | hsa:50487 | path:hsa04975 | Fat digestion and absorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | PLA2G3 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CTCF | PLA2G3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PLA2G3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |