GENE:PSMB10
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PSMB10 |
| FullNmae | proteasome 20S subunit beta 10 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9538 |
| EnsembleID | ENSG00000205220 |
| Uniprot | P40306 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PSMB10 | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PSMB10 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| PSMB10 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PSMB10 | GO:0000502,GO:0000902,GO:0004175,GO:0004298,GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0005839,GO:0006959,GO:0010498,GO:0019774,GO:0019774,GO:0042098,GO:1990111 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PSMB10 | hsa:5699 | path:hsa03050 | Proteasome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PSMB10 | IRF1 | 10575004 18694960 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| PSMB10 | IRF2 | 10575004 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| PSMB10 | RELA | 18694960 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| PSMB10 | PRDM1 | 20421211 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| PSMB10 | IRF8 | 22096565 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | PSMB10 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | PSMB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | PSMB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PSMB10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IRF1 | PSMB10 | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB1 | PSMB10 | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RELA | PSMB10 | 18694960 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PSMA4 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA4 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMA6 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA6 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMC4 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMC4 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD6 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD6 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD8 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD8 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD1 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD1 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMC1 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMC1 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB1 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMB1 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMA5 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA5 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMA1 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA1 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB3 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMB3 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PIPSL | 25361965 | interaction type | N/A | PTMCode2 |
| PIPSL | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA7 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMA7 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMB2 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB2 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD14 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD14 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD11 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD11 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB7 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMB7 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB4 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMB4 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMD7 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMD7 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMA3 | PSMB10 | 25361965 | interaction type | N/A | PTMCode2 |
| PSMB10 | PSMA3 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CRX | PSMB10 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PSMB10 | MEOX2 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PSMB10 | PSMB9 | 10329130 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| PSMB10 | PTN | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PSMB10 | ANXA7 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PSMB10 | PSMA2 | 15887188 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PSMB10 | PSMA1 | 14733938 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PSMB10 | PSMB3 | 14733938 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PSMB10 | PSMB8 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | POMP | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMA3 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMB6 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSME1 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSME2 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMB1 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMB5 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMD6 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | CCNDBP1 | 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| PSMB10 | PSMD4 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMD5 | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | MYH9 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PSMB10 | TARDBP | 25348397 | N/A | physical interaction | ComPPI |
| PSMB10 | PSMB7 | 20723761 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| PSMB10 | DDIT4L | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PSMB4 | PSMB10 | 25348397 | N/A | physical interaction | ComPPI |
| H3-4 | PSMB10 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| IFNG | PSMB10 | 27898060 8811196 | stimulant | N/A | OmniPath |
