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GENE：CD244

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD244
FullNmae CD244 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18171
EnsembleID ENSG00000122223
Uniprot Q9BZW8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD244 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CD244 GO:0002250,GO:0002323,GO:0002323,GO:0005515,GO:0005886,GO:0007165,GO:0009897,GO:0009897,GO:0032729,GO:0032757,GO:0038023,GO:0042288,GO:0042288,GO:0045087,GO:0060732,GO:0071663

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD244 hsa:51744 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SH2D1A CD244 15187115 19150402 23180781 physical association anti tag coimmunoprecipitation,peptide array InnateDB

Source Target Pmid Interactiontype Methods Database
LAT CD244 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
E2F4 CD244 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CD244 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CD244 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CD244 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 CD244 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000553F51 CD244 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 CD244 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 CD244 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D CD244 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 CD244 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LAT CD244 12077228 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN6 CD244 11489943 24234451 24642916 25348397 association,physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
SH3BP2 CD244 16177062 24234451 25348397 physical association three hybrid ComPPI,IntAct
PIK3R1 CD244 25348397 N/A physical interaction ComPPI
PTPN11 CD244 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
INPP5D CD244 24234451 24642916 25348397 26221972 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
PLCG2 CD244 24234451 24642916 25348397 N/A surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct
GRB2 CD244 24234451 24642916 25348397 association pull down ComPPI,IntAct
INPPL1 CD244 24234451 24642916 25348397 association pull down ComPPI,IntAct
CD247 CD244 14525934 16049493 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ST7 CD244 25348397 N/A physical interaction ComPPI
CSK CD244 24234451 24642916 25348397 association pull down ComPPI,IntAct
ARFGEF1 CD244 25348397 N/A physical interaction ComPPI
PTPRC CD244 23346089 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SH2D1A CD244 11489943 16920955 23346089 24234451 24642916 25348397 26221972 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,surface plasmon resonance,physical interaction,surface plasmon resonance array ComPPI,IntAct
FYN CD244 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
ARHGEF7 CD244 14525934 16983070 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
B2M CD244 20164429 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CD48 CD244 11163399 14525934 15153464 16002700 18296487 24234451 25348397 9834056 physical association experimental interaction detection,fluorescence-activated cell sorting,in vitro,in vivo,solid phase assay ComPPI,HPRD,IntAct
CD244 SH2D1B 11689425 14525934 23346089 24234451 24642916 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,surface plasmon resonance,in vitro,in vivo,surface plasmon resonance array,two hybrid ComPPI,HPRD,IntAct
CD244 IMMT 25348397 N/A physical interaction ComPPI
CD244 CAND2 25348397 N/A physical interaction ComPPI
CD244 HEATR1 25348397 N/A physical interaction ComPPI
CD244 HEATR6 25348397 N/A physical interaction ComPPI
CD244 PDXDC1 25348397 N/A physical interaction ComPPI
CD244 PI4KA 25348397 N/A physical interaction ComPPI
CD244 ARFGEF2 25348397 N/A physical interaction ComPPI
CD244 MTOR 25348397 N/A physical interaction ComPPI
CD244 POMT2 25348397 N/A physical interaction ComPPI
CD244 POMT1 25348397 N/A physical interaction ComPPI
CD244 UFSP2 25348397 N/A physical interaction ComPPI
CD244 LTN1 25348397 N/A physical interaction ComPPI
CD244 RNF213 25348397 N/A physical interaction ComPPI
CD244 MTX2 25348397 N/A physical interaction ComPPI
CD244 MTX3 25348397 N/A physical interaction ComPPI
CD244 MYADM 25348397 N/A physical interaction ComPPI
CD244 CARD19 25348397 N/A physical interaction ComPPI
CD244 TSPOAP1 25348397 N/A physical interaction ComPPI
CD244 CHCHD6 25348397 N/A physical interaction ComPPI
CD244 PLCG1 24234451 24642916 25348397 association pull down,surface plasmon resonance,surface plasmon resonance array ComPPI,IntAct

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