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GENE：PSMB2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMB2
FullNmae proteasome 20S subunit beta 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9539
EnsembleID ENSG00000126067
Uniprot P49721

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMB2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMB2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMB2 GO:0000502,GO:0000502,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0005839,GO:0010243,GO:0010498,GO:0014070,GO:0016020,GO:0019774,GO:0019774,GO:0043161,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMB2 hsa:5690 path:hsa03050 Proteasome - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05020 Prion disease - Homo sapiens (human)
PSMB2 hsa:5690 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSMB2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMB2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PSMB2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMB2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PSMB2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PSMB2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002971AB PSMB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE PSMB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PSMB2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003E226A PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 PSMB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD PSMB2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000005CE28 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEF5F PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B7450 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D5FFC PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 PSMB2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA4 25361965 interaction type N/A PTMCode2
SKP1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 SKP1 25361965 interaction type N/A PTMCode2
USP14 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 USP14 25361965 interaction type N/A PTMCode2
PSMD1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMD1 25361965 interaction type N/A PTMCode2
PSMC1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMC1 25361965 interaction type N/A PTMCode2
PSMB2 PSMC6 25361965 interaction type N/A PTMCode2
PSMC6 PSMB2 25361965 interaction type N/A PTMCode2
PSMA5 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA5 25361965 interaction type N/A PTMCode2
PSMA1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA1 25361965 interaction type N/A PTMCode2
PSMB10 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMB10 25361965 interaction type N/A PTMCode2
PSMD11 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMD11 25361965 interaction type N/A PTMCode2
PSMA7 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA7 25361965 interaction type N/A PTMCode2
PSMD7 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMD7 25361965 interaction type N/A PTMCode2
PSMA3 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMA3 25361965 interaction type N/A PTMCode2
PSMD10 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMD10 25361965 interaction type N/A PTMCode2
CUL1 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 CUL1 25361965 interaction type N/A PTMCode2
PSMC3 PSMB2 25361965 interaction type N/A PTMCode2
PSMB2 PSMC3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GET3 PSMB2 25348397 N/A physical interaction ComPPI
KCTD9 PSMB2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP19-5 PSMB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VIM PSMB2 25348397 N/A physical interaction ComPPI
PSMC3 PSMB2 25348397 N/A physical interaction ComPPI
PSMC6 PSMB2 25348397 N/A physical interaction ComPPI
TRAF6 PSMB2 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
PSMB2 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PSMB2 PSMA1 12376572 14525934 14733938 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,two hybrid,pull down,x-ray crystallography,physical interaction,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
PSMB2 PSMB3 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB2 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 UBC 25348397 N/A physical interaction ComPPI
PSMB2 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 RAD23A 25348397 N/A physical interaction ComPPI
PSMB2 FKBP8 25348397 N/A physical interaction ComPPI
PSMB2 UCHL5 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 POMP 17948026 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB2 PSMB5 14733938 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMB2 PSMB7 20723761 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 PSMA3 25348397 N/A physical interaction ComPPI
PSMB2 PSMA4 25348397 N/A physical interaction ComPPI
PSMB2 PSMA5 25348397 N/A physical interaction ComPPI
PSMB2 PSMA6 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 PSMA7 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 PSMB6 25348397 N/A physical interaction ComPPI
PSMB2 PSMB8 25348397 N/A physical interaction ComPPI
PSMB2 PSMC1 25348397 N/A physical interaction ComPPI
PSMB2 PSMC4 25348397 N/A physical interaction ComPPI
PSMB2 PSMC2 25348397 N/A physical interaction ComPPI
PSMB2 PSMC5 25348397 N/A physical interaction ComPPI
PSMB2 PSMD11 25348397 N/A physical interaction ComPPI
PSMB2 PSMD7 25348397 N/A physical interaction ComPPI
PSMB2 PSMD1 25348397 N/A physical interaction ComPPI
PSMB2 PSMD2 25348397 N/A physical interaction ComPPI
PSMB2 PSMD8 25348397 N/A physical interaction ComPPI
PSMB2 PSMD6 25348397 N/A physical interaction ComPPI
PSMB2 PSMD12 25348397 N/A physical interaction ComPPI
PSMB2 PSMD13 25348397 N/A physical interaction ComPPI
PSMB2 PSMD3 25348397 N/A physical interaction ComPPI
PSMB2 PSMD14 25348397 N/A physical interaction ComPPI
PSMB2 PSMD4 25348397 N/A physical interaction ComPPI
PSMB2 PSME1 25348397 N/A physical interaction ComPPI
PSMB2 PSMD5 25348397 N/A physical interaction ComPPI
PSMB2 PSME3 25348397 N/A physical interaction ComPPI
PSMB2 PSMA8 25348397 N/A physical interaction ComPPI
PSMB2 UBA52 25348397 N/A physical interaction ComPPI
PSMB2 RAD23B 25348397 N/A physical interaction ComPPI
PSMB2 TST 25348397 N/A physical interaction ComPPI
PSMB2 UBE2A 25348397 N/A physical interaction ComPPI
PSMB2 FOLR1 25348397 N/A physical interaction ComPPI
PSMB2 YBX1 25348397 N/A physical interaction ComPPI
PSMB2 HRAS 25348397 N/A physical interaction ComPPI
PSMB2 SMARCA2 25348397 N/A physical interaction ComPPI
PSMB2 TUBB 25348397 N/A physical interaction ComPPI
PSMB2 SMAP 25348397 N/A physical interaction ComPPI
PSMB2 PIR 25348397 N/A physical interaction ComPPI
PSMB2 UBE2B 25348397 N/A physical interaction ComPPI
PSMB2 SEC23A 25348397 N/A physical interaction ComPPI
PSMB2 SULT1A3 25348397 N/A physical interaction ComPPI
PSMB2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PSMB2 VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PSMB2 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB2 ITGA4 25348397 N/A physical interaction ComPPI
PSMB2 PRKN 25348397 N/A physical interaction ComPPI
PSMB2 GPX2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMB2 DDX49 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMB2 CDK20 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMB2 HOXA2 25348397 N/A physical interaction ComPPI
PSMB2 PYCR3 25348397 N/A physical interaction ComPPI
PSMB2 KRT13 25348397 N/A physical interaction ComPPI
PSMB2 AMFR 25348397 N/A physical interaction ComPPI
PSMB2 SYVN1 25348397 N/A physical interaction ComPPI
PSMB2 PSMB9 25348397 N/A physical interaction ComPPI
PSMB2 HSPB1 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
PSMB2 AMBRA1 25348397 N/A physical interaction ComPPI
PSMB2 ACACA 25348397 N/A physical interaction ComPPI
PSMB2 ADRM1 25348397 N/A physical interaction ComPPI
PSMB2 MRPS9 25348397 N/A physical interaction ComPPI
PSMB2 PGK1 25348397 N/A physical interaction ComPPI
PSMB2 YWHAE 25348397 N/A physical interaction ComPPI
PSMB2 XPOT 25348397 N/A physical interaction ComPPI
PSMB2 MCM2 25348397 N/A physical interaction ComPPI
PSMB2 POU5F1 25348397 N/A physical interaction ComPPI
PSMB2 UBLCP1 25348397 N/A physical interaction ComPPI
PSMB2 PSME4 25348397 N/A physical interaction ComPPI
PSMB2 AKIRIN2 25348397 N/A physical interaction ComPPI
PSMB2 PSMG2 25348397 N/A physical interaction ComPPI
PSMB2 PSME2 25348397 N/A physical interaction ComPPI
PSMB2 PSMF1 25348397 N/A physical interaction ComPPI
PSMB2 FBXO7 25348397 N/A physical interaction ComPPI
PSMB2 PSMG1 25348397 N/A physical interaction ComPPI
PSMB2 CYLD 25348397 N/A physical interaction ComPPI
PSMB2 CFTR 25348397 N/A physical interaction ComPPI
PSMB2 KEAP1 25348397 N/A physical interaction ComPPI
PSMB2 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMB2 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB2 SKP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB2 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PSMB2 KRTAP19-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB2 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB2 AXIN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB2 KRTAP19-6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP19-7 PSMB2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PYGB PSMB2 25348397 N/A physical interaction ComPPI
PSMB4 PSMB2 25348397 N/A physical interaction ComPPI
PSMB1 PSMB2 17948026 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DAG1 PSMB2 24234451 association cross-linking study IntAct

Visualization










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