GENE：INHBB
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | INHBB |
| FullNmae | inhibin subunit beta B |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:6067 |
| EnsembleID | ENSG00000163083 |
| Uniprot | P09529 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| INHBB | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| INHBB | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| INHBB | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| INHBB | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| INHBB | GO:0001541,GO:0005125,GO:0005125,GO:0005179,GO:0005515,GO:0005576,GO:0005615,GO:0006952,GO:0007283,GO:0008083,GO:0009267,GO:0009611,GO:0017085,GO:0021983,GO:0030154,GO:0032686,GO:0032869,GO:0032924,GO:0034698,GO:0042803,GO:0044320,GO:0044650,GO:0045444,GO:0046676,GO:0046789,GO:0046881,GO:0046882,GO:0048471,GO:0048599,GO:0060279,GO:0071277,GO:0071320,GO:0071347,GO:0071397,GO:0071944,GO:0072520,GO:0097067,GO:0097190,GO:1904017,GO:2001235 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| INHBB | hsa:3625 | path:hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| INHBB | hsa:3625 | path:hsa04350 | TGF-beta signaling pathway - Homo sapiens (human) |
| INHBB | hsa:3625 | path:hsa04550 | Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GATA2 | INHBB | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| CEBPA | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | INHBB | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | INHBB | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000EED18 | INHBB | 24446339 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ACVR1C | INHBB | 25361965 | interaction type | N/A | PTMCode2 |
| INHBB | ACVR1C | 25361965 | interaction type | N/A | PTMCode2 |
| ACVR2A | INHBB | 25361965 | interaction type | N/A | PTMCode2 |
| INHBB | ACVR2A | 25361965 | interaction type | N/A | PTMCode2 |
| ACVR1 | INHBB | 25361965 | interaction type | N/A | PTMCode2 |
| INHBB | ACVR1 | 25361965 | interaction type | N/A | PTMCode2 |
| INHBB | ACVR2B | 25361965 | interaction type | N/A | PTMCode2 |
| ACVR2B | INHBB | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ACVR1B | INHBB | 11266516 12032389 14525934 15196700 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| ACVR1C | INHBB | 14525934 15196700 24234451 25241761 25348397 | physical association | experimental interaction detection,physical interaction,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
| IGSF1 | INHBB | 11266516 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| ACVR2B | INHBB | 14525934 25348397 9202237 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| ACVR1 | INHBB | 11266516 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| FNTA | INHBB | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| INHBA | INHBB | 11134153 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| INHBB | ACVR2A | 11266516 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| INHBB | INHBC | 11134153 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| INHA | INHBB | 11134153 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| INHBB | INHBB | 11266516 14525934 | N/A | experimental interaction detection | HPRD |
| INHBB | BAMBI | 10918299 27898060 | stimulant | N/A | OmniPath |