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GENE：PSMA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMA2
FullNmae proteasome 20S subunit alpha 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9531
EnsembleID ENSG00000106588
Uniprot P25787

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMA2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMA2 GO:0000502,GO:0000502,GO:0000932,GO:0005515,GO:0005576,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0005839,GO:0009615,GO:0010498,GO:0019773,GO:0019773,GO:0034774,GO:0043161,GO:0043161,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMA2 hsa:5683 path:hsa03050 Proteasome - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05020 Prion disease - Homo sapiens (human)
PSMA2 hsa:5683 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSMA2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PSMA2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PSMA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000028BB8 PSMA2 17612493 20371350 23446348 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS0000272A3D PSMA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PSMA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B2B5C PSMA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B PSMA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 PSMA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000195F5B PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FB065 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000015188E PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 PSMA2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EXOSC5 PSMA2 25348397 N/A physical interaction ComPPI
CDC5L PSMA2 25348397 N/A physical interaction ComPPI
EIF1B PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPA8 PSMA2 25348397 N/A physical interaction ComPPI
PSMB10 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GET3 PSMA2 25348397 N/A physical interaction ComPPI
PAK2 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BAG3 PSMA2 25348397 N/A physical interaction ComPPI
VIM PSMA2 25348397 N/A physical interaction ComPPI
SNRPA1 PSMA2 25348397 N/A physical interaction ComPPI
PSMC3 PSMA2 25348397 N/A physical interaction ComPPI
PSMC6 PSMA2 25348397 N/A physical interaction ComPPI
KIF5B PSMA2 25348397 N/A physical interaction ComPPI
PSMD14 PSMA2 25348397 N/A physical interaction ComPPI
TRAF6 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD7 PSMA2 25348397 N/A physical interaction ComPPI
VCP PSMA2 25348397 N/A physical interaction ComPPI
SKP1 PSMA2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
KEAP1 PSMA2 25348397 N/A physical interaction ComPPI
PSMB2 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HSP90AB1 PSMA2 25348397 N/A physical interaction ComPPI
PNMA2 PSMA2 25348397 N/A physical interaction ComPPI
FBXW7 PSMA2 25348397 N/A physical interaction ComPPI
JUN PSMA2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
USP7 PSMA2 25348397 N/A physical interaction ComPPI
PSMA3 PSMA2 14525934 14733938 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMD11 PSMA2 25348397 N/A physical interaction ComPPI
U2AF2 PSMA2 25348397 N/A physical interaction ComPPI
RBX1 PSMA2 25348397 N/A physical interaction ComPPI
SERPINH1 PSMA2 25348397 N/A physical interaction ComPPI
UBB PSMA2 25348397 N/A physical interaction ComPPI
UBC PSMA2 25348397 N/A physical interaction ComPPI
NTRK1 PSMA2 25348397 N/A physical interaction ComPPI
YBX1 PSMA2 25348397 N/A physical interaction ComPPI
HSPA5 PSMA2 25348397 N/A physical interaction ComPPI
HUS1 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PLK1 PSMA2 25348397 N/A physical interaction ComPPI
PSMA1 PSMA2 12376572 14525934 14733938 15225636 21988832 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,anti bait coimmunoprecipitation,two hybrid,cosedimentation in solution,pull down,x-ray crystallography,physical interaction,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
PSMA6 PSMA2 14525934 14733938 15887188 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMA5 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB9 PSMA2 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
MYC PSMA2 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFKBIA PSMA2 25348397 N/A physical interaction ComPPI
EEF1A1 PSMA2 25348397 N/A physical interaction ComPPI
CFTR PSMA2 25348397 N/A physical interaction ComPPI
PSMD8 PSMA2 25348397 N/A physical interaction ComPPI
TPM3 PSMA2 25348397 N/A physical interaction ComPPI
PSMB8 PSMA2 25348397 N/A anti bait coimmunoprecipitation,physical interaction ComPPI
PSMD1 PSMA2 25348397 N/A physical interaction ComPPI
TNIK PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SYVN1 PSMA2 25348397 N/A physical interaction ComPPI
PSMC5 PSMA2 25348397 N/A physical interaction ComPPI
ABCE1 PSMA2 25348397 N/A physical interaction ComPPI
HUWE1 PSMA2 25348397 N/A physical interaction ComPPI
UBQLN2 PSMA2 25348397 N/A physical interaction ComPPI
RAD23A PSMA2 25348397 N/A physical interaction ComPPI
UBA2 PSMA2 25348397 N/A physical interaction ComPPI
HOMER3 PSMA2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NEDD8 PSMA2 25348397 N/A physical interaction ComPPI
CUL1 PSMA2 25348397 N/A physical interaction ComPPI
VHL PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMC4 PSMA2 25348397 N/A physical interaction ComPPI
CCT7 PSMA2 25348397 N/A physical interaction ComPPI
MED23 PSMA2 25348397 N/A physical interaction ComPPI
EXOSC6 PSMA2 25348397 N/A physical interaction ComPPI
NOS2 PSMA2 25348397 N/A physical interaction ComPPI
PSMD2 PSMA2 25348397 N/A physical interaction ComPPI
ZNF24 PSMA2 25348397 N/A physical interaction ComPPI
RAD23B PSMA2 25348397 N/A physical interaction ComPPI
RANBP10 PSMA2 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PRKN PSMA2 25348397 N/A physical interaction ComPPI
PSMD4 PSMA2 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CAND1 PSMA2 25348397 N/A physical interaction ComPPI
FKBP8 PSMA2 25348397 N/A physical interaction ComPPI
PSMB5 PSMA2 14525934 14733938 15887188 24234451 25348397 association anti bait coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSME3 PSMA2 25348397 N/A physical interaction ComPPI
PSME1 PSMA2 25348397 N/A physical interaction ComPPI
PSME2 PSMA2 25348397 N/A physical interaction ComPPI
ELP1 PSMA2 25348397 N/A physical interaction ComPPI
TERF1 PSMA2 25348397 N/A physical interaction ComPPI
PSMC1 PSMA2 25348397 N/A physical interaction ComPPI
AMFR PSMA2 25348397 N/A physical interaction ComPPI
CLIC4 PSMA2 25348397 N/A physical interaction ComPPI
FBXO7 PSMA2 25348397 N/A physical interaction ComPPI
PSMB4 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB1 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB7 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA7 PSMA2 14525934 15225636 17948026 21900206 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
PSMA4 PSMA2 14525934 14733938 15225636 15887188 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
SOD1 PSMA2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EXOSC2 PSMA2 25348397 N/A physical interaction ComPPI
EXOSC9 PSMA2 25348397 N/A physical interaction ComPPI
PSMD5 PSMA2 25348397 N/A physical interaction ComPPI
IQCB1 PSMA2 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCTN2 PSMA2 25348397 N/A physical interaction ComPPI
IKBKE PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BCAR3 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MPG PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRPF19 PSMA2 25348397 N/A physical interaction ComPPI
UCHL5 PSMA2 18922472 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HEATR1 PSMA2 25348397 N/A physical interaction ComPPI
MED4 PSMA2 25348397 N/A physical interaction ComPPI
NME2 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ADRM1 PSMA2 25348397 N/A physical interaction ComPPI
PSMD13 PSMA2 25348397 N/A physical interaction ComPPI
PSMD12 PSMA2 25348397 N/A physical interaction ComPPI
PSMF1 PSMA2 25348397 N/A physical interaction ComPPI
PSMC2 PSMA2 25348397 N/A physical interaction ComPPI
PSMD6 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA2 PSMB6 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA2 PCK1 25348397 N/A physical interaction ComPPI
PSMA2 PSMD3 25348397 N/A physical interaction ComPPI
PSMA2 PAAF1 25348397 N/A physical interaction ComPPI
PSMA2 USP14 25348397 N/A physical interaction ComPPI
PSMA2 CCT3 25348397 N/A physical interaction ComPPI
PSMA2 CRBN 25348397 N/A physical interaction ComPPI
PSMA2 ZC3H4 25348397 N/A physical interaction ComPPI
PSMA2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PSMA2 PPP4R3A 25348397 N/A physical interaction ComPPI
PSMA2 AMBRA1 25348397 N/A physical interaction ComPPI
PSMA2 ATG5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA2 HLA-C 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HADH PSMA2 25348397 N/A physical interaction ComPPI
DAG1 PSMA2 24234451 association cross-linking study IntAct

Visualization










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