Gene Information gene info

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GENE：PSMA8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMA8
FullNmae proteasome 20S subunit alpha 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:22985
EnsembleID ENSG00000154611
Uniprot Q8TAA3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMA8 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMA8 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMA8 GO:0005634,GO:0005634,GO:0005634,GO:0005829,GO:0006511,GO:0007283,GO:0010498,GO:0010498,GO:0019773,GO:0019773,GO:0030154,GO:0051321,GO:0060631,GO:0070062,GO:1990111

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMA8 hsa:143471 path:hsa03050 Proteasome - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05020 Prion disease - Homo sapiens (human)
PSMA8 hsa:143471 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PSMA8 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PSMA8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF PSMA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PSMA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PSMA8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
VIM PSMA8 25348397 N/A physical interaction ComPPI
PSMC3 PSMA8 25348397 N/A physical interaction ComPPI
PSMC6 PSMA8 25348397 N/A physical interaction ComPPI
PSMD14 PSMA8 25348397 N/A physical interaction ComPPI
PSMD7 PSMA8 25348397 N/A physical interaction ComPPI
MCM2 PSMA8 25348397 N/A physical interaction ComPPI
PSMB2 PSMA8 25348397 N/A physical interaction ComPPI
PSMA3 PSMA8 25348397 N/A physical interaction ComPPI
PSMA1 PSMA8 25348397 N/A physical interaction ComPPI
PSMA6 PSMA8 25348397 N/A physical interaction ComPPI
PSMA5 PSMA8 25348397 N/A physical interaction ComPPI
PSMB9 PSMA8 25348397 N/A physical interaction ComPPI
CFTR PSMA8 25348397 N/A physical interaction ComPPI
PSMD8 PSMA8 25348397 N/A physical interaction ComPPI
PSMB8 PSMA8 25348397 N/A physical interaction ComPPI
PSMD1 PSMA8 25348397 N/A physical interaction ComPPI
PSMC5 PSMA8 25348397 N/A physical interaction ComPPI
MDM2 PSMA8 25348397 N/A physical interaction ComPPI
PSMC4 PSMA8 25348397 N/A physical interaction ComPPI
PSMD2 PSMA8 25348397 N/A physical interaction ComPPI
PSMB5 PSMA8 25348397 N/A physical interaction ComPPI
PSME3 PSMA8 25348397 N/A physical interaction ComPPI
PSMC1 PSMA8 25348397 N/A physical interaction ComPPI
PSMB4 PSMA8 25348397 N/A physical interaction ComPPI
PSMB1 PSMA8 25348397 N/A physical interaction ComPPI
PSMB3 PSMA8 25348397 N/A physical interaction ComPPI
PSMB7 PSMA8 25348397 N/A physical interaction ComPPI
PSMA7 PSMA8 25348397 N/A physical interaction ComPPI
PSMA4 PSMA8 25348397 N/A physical interaction ComPPI
PSMD13 PSMA8 25348397 N/A physical interaction ComPPI
PSMC2 PSMA8 25348397 N/A physical interaction ComPPI
PSMD6 PSMA8 25348397 N/A physical interaction ComPPI
XBP1 PSMA8 25348397 N/A physical interaction ComPPI
PSMD3 PSMA8 25348397 N/A physical interaction ComPPI
PSMB6 PSMA8 25348397 N/A physical interaction ComPPI
H2BC9 PSMA8 24234451 30021884 physical association cross-linking study IntAct

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