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GENE：CSF2RB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CSF2RB
FullNmae colony stimulating factor 2 receptor subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2436
EnsembleID ENSG00000100368
Uniprot P32927

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CSF2RB pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CSF2RB apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CSF2RB GO:0004896,GO:0004912,GO:0004914,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0007165,GO:0007259,GO:0007585,GO:0009897,GO:0015026,GO:0016064,GO:0019221,GO:0030526,GO:0030526,GO:0032496,GO:0036016,GO:0038023,GO:0038043,GO:0038156,GO:0038157,GO:0070665

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CSF2RB hsa:1439 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CSF2RB hsa:1439 path:hsa04210 Apoptosis - Homo sapiens (human)
CSF2RB hsa:1439 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
CSF2RB hsa:1439 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CSF2RB CSF2RA 11015446 11306493 11777960 11867689 12393492 12811837 14610620 18322230 19833085 20406969 20805416 21765015 22323450 22869907 23046136 23180781 24030977 24091328 26192618 27216177 interaction type,physical association anti tag coimmunoprecipitation ACSN,InnateDB
CSF2 CSF2RB 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 26192618 27216177 interaction type N/A ACSN
JAK2 CSF2RB 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 26192618 27216177 interaction type N/A ACSN
CSF2RB IL3 11698286 12393492 15034038 15549123 15573129 17200410 18633355 22323450 23026134 23046136 23125331 23762788 24778133 26192618 interaction type N/A ACSN
CSF2RB STAT1 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 26192618 27216177 interaction type N/A ACSN
CSF2RB STAT6 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 26192618 27216177 interaction type N/A ACSN
BCR CSF2RB 23180781 8758906 phosphorylation reaction,physical association anti tag coimmunoprecipitation,protein kinase assay InnateDB
CSF2RB IL5RA 1495999 23180781 physical association protein cross-linking with a bifunctional reagent InnateDB
CSF2RB IL5 1495999 23180781 physical association protein cross-linking with a bifunctional reagent InnateDB
CSF2RB SHC1 23180781 8647804 physical association pull down InnateDB
CSF2RB TRAF6 20622119 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RB CEBPA 10453008 23180781 physical association electrophoretic mobility supershift assay InnateDB
CSF2RB CEBPB 10453008 23180781 physical association electrophoretic mobility supershift assay InnateDB
CEBPE CSF2RB 10453008 23180781 physical association electrophoretic mobility supershift assay InnateDB
CSF2RB ICAM1 18322230 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RB PTPN11 18322230 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RB FYN 18322230 23180781 physical association anti tag coimmunoprecipitation InnateDB
LCP1 CSF2RB 21525390 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RB LCP1 21525390 23180781 physical association anti tag coimmunoprecipitation InnateDB
CSF2RA CSF2RB 10572088 23180781 physical association saturation binding InnateDB

Source Target Pmid Interactiontype Methods Database
CISH CSF2RB 20005715 interaction type N/A PSP
SHC1 CSF2RB 20005715 interaction type N/A PSP
YWHAZ CSF2RB 20005715 interaction type N/A PSP
CISH CSF2RB 20005715 20005715 N/A N/A SignaLink
YWHAZ CSF2RB 10477722 10477722 10477722 18988627 20005715 20005715 21071413 8278375 N/A N/A SignaLink
SHC1 CSF2RB 10477722 10704825 10704825 18988627 20005715 20005715 21071413 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
GATA2 CSF2RB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CSF2RB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CSF2RB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CSF2RB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC CSF2RB N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
LYN CSF2RB 22135298 phosphorylation N/A PhosphoSite
CSF2RB PTPN6 25361965 interaction type N/A PTMCode2
PTPN6 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB SHC1 25361965 interaction type N/A PTMCode2
SHC1 CSF2RB 25361965 interaction type N/A PTMCode2
FYN CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB FYN 25361965 interaction type N/A PTMCode2
JAK1 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB JAK1 25361965 interaction type N/A PTMCode2
EPOR CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB EPOR 25361965 interaction type N/A PTMCode2
YWHAB CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB YWHAB 25361965 interaction type N/A PTMCode2
KIT CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB KIT 25361965 interaction type N/A PTMCode2
CSF2 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB CSF2 25361965 interaction type N/A PTMCode2
IL3RA CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB IL3RA 25361965 interaction type N/A PTMCode2
IL5 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB IL5 25361965 interaction type N/A PTMCode2
JAK2 CSF2RB 25361965 interaction type N/A PTMCode2
CSF2RB JAK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STAT1 CSF2RB 14525934 25348397 8631962 N/A experimental interaction detection,in vivo ComPPI,HPRD
CSF2 CSF2RB 14525934 18692472 24234451 25348397 2645577 8278375 physical association cross-linking study,experimental interaction detection,x-ray crystallography,physical interaction,biochemical,saturation binding,in vitro,in vivo ComPPI,HPRD,IntAct
PTPN6 CSF2RB 14525934 24234451 25348397 7528537 8246974 9162089 9254654 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RACK1 CSF2RB 10490850 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
SYK CSF2RB 14525934 25348397 8666899 N/A experimental interaction detection,in vivo ComPPI,HPRD
SOCS1 CSF2RB 25348397 N/A physical interaction ComPPI
KIT CSF2RB 14525934 15308671 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LYN CSF2RB 14525934 25348397 7636265 9973406 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PIK3R1 CSF2RB 16437163 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
PTPN11 CSF2RB 14525934 24234451 25348397 9162089 9254654 9973406 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
LCK CSF2RB 14525934 1638019 25348397 7896837 N/A experimental interaction detection,in vitro ComPPI,HPRD
KDR CSF2RB 14525934 16007196 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SHC1 CSF2RB 10477722 10704825 14525934 16437163 24234451 25348397 association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
ITGB1 CSF2RB 20802515 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,pull down ComPPI,IntAct,OmniPath
YWHAZ CSF2RB 10477722 14525934 24234451 25348397 8278375 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
FES CSF2RB 14525934 25348397 8631962 N/A experimental interaction detection,in vivo ComPPI,HPRD
CSF2RA CSF2RB 14525934 25348397 9211889 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PIK3CA CSF2RB 25348397 N/A phosphorylation reaction,protein kinase assay ComPPI
JAK1 CSF2RB 11557047 14525934 24234451 25348397 9516124 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
CISH CSF2RB 14525934 25348397 7796808 N/A experimental interaction detection,in vitro ComPPI,HPRD
IKBKB CSF2RB 25348397 N/A physical interaction ComPPI
PRKCB CSF2RB 10490850 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
STAT5A CSF2RB 16437163 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EPOR CSF2RB 12488507 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
JAK2 CSF2RB 10772872 14525934 16437163 18692472 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
FYN CSF2RB 14525934 25348397 9195918 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
IL3RA CSF2RB 14525934 25348397 8649415 N/A experimental interaction detection,in vitro ComPPI,HPRD
AKT1 CSF2RB 16437163 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAD2L1 CSF2RB 11551900 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
STAT3 CSF2RB 14525934 25348397 8631962 N/A experimental interaction detection,in vivo ComPPI,HPRD
HCK CSF2RB 14525934 25348397 9195918 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CSF2RB IL3 14525934 18692472 24234451 25348397 9278420 physical association experimental interaction detection,physical interaction,biochemical,saturation binding,in vitro,in vivo ComPPI,HPRD,IntAct
CSF2RB IL5RA 14525934 1495999 24234451 25348397 9516124 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,saturation binding ComPPI,HPRD,IntAct
CSF2RB IL5 1495999 24234451 25348397 physical association cross-linking study,experimental interaction detection,physical interaction,biochemical,saturation binding ComPPI,IntAct
CSF2RB CSF2RB 10753826 11207369 14525934 8666948 N/A experimental interaction detection HPRD
LYN CSF2RB 10329850 10672044 27898060 7636265 9973406 stimulant N/A OmniPath
CSF2RB IL3RA 11700046 27898060 8649415 N/A N/A OmniPath
CSF2RB CSF2RA 10572088 10753826 18322230 27898060 2828352 9211889 N/A N/A OmniPath
CSF2RB TRAF6 20622119 27898060 N/A N/A OmniPath
IL5RA CSF2RB 1495999 27898060 9516124 N/A N/A OmniPath
PTPN6 CSF2RB 11812650 27898060 7528537 8246974 9162089 9254654 inhibition N/A OmniPath
SHC1 CSF2RB 10477722 10704825 27898060 8647804 N/A N/A OmniPath
CSF2RB SHC1 10477722 10704825 27898060 8647804 stimulant N/A OmniPath
BCR CSF2RB 27898060 8758906 N/A N/A OmniPath
CSF2RB BCR 27898060 8758906 N/A N/A OmniPath
CSF2RB PTPN11 18322230 27898060 9162089 9254654 9973406 N/A N/A OmniPath
PTPN11 CSF2RB 18322230 27898060 9162089 9254654 9973406 inhibition,stimulant N/A OmniPath
LCP1 CSF2RB 21525390 27898060 N/A N/A OmniPath
IL5 CSF2RB 1495999 27898060 7957082 stimulant N/A OmniPath
ITK CSF2RB 10329850 10362354 10949031 16437163 27898060 9257712 N/A N/A OmniPath

Visualization










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