Gene Information gene info

GENE:PSMD3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMD3
FullNmae proteasome 26S subunit, non-ATPase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9560
EnsembleID ENSG00000108344
Uniprot O43242

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMD3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD3 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMD3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMD3 GO:0000502,GO:0000502,GO:0005515,GO:0005576,GO:0005634,GO:0005654,GO:0005829,GO:0006511,GO:0008541,GO:0016020,GO:0022624,GO:0030234,GO:0034774,GO:0042176,GO:0043161,GO:0070062,GO:1904813

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMD3 hsa:5709 path:hsa03050 Proteasome - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05020 Prion disease - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PSMD3 hsa:5709 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CIITA PSMD3 18437201 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRAF6 PSMD3 14743216 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR PSMD3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PSMD3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PSMD3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PSMD3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMD3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PSMD3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PSMD3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRCA2 PSMD3 17563742 trascriptional regulation,stimulation inferred by curator TFlink
MYC PSMD3 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000512C88 PSMD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004E008F PSMD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 PSMD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 PSMD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PSMD3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000014F13C PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002394F5 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A PSMD3 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GNAI3 PSMD3 25348397 N/A physical interaction ComPPI
BCAS2 PSMD3 25348397 N/A physical interaction ComPPI
SNW1 PSMD3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L PSMD3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ZBTB43 PSMD3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BAG3 PSMD3 25348397 N/A physical interaction ComPPI
RPS28 PSMD3 25348397 N/A physical interaction ComPPI
PSMC3 PSMD3 25348397 N/A physical interaction ComPPI
PSMC6 PSMD3 25348397 N/A physical interaction ComPPI
SNAI2 PSMD3 25348397 N/A physical interaction ComPPI
PSMD14 PSMD3 19615732 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 PSMD3 14743216 24234451 25348397 physical association physical interaction,tandem affinity purification ComPPI,IntAct
PSMD7 PSMD3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPN6 PSMD3 25348397 N/A pull down ComPPI
MCM2 PSMD3 25348397 N/A physical interaction ComPPI
PSMB2 PSMD3 25348397 N/A physical interaction ComPPI
ABRAXAS2 PSMD3 19214193 24234451 25348397 association biochemical ComPPI,IntAct
SF3A2 PSMD3 25348397 N/A physical interaction ComPPI
PLCG2 PSMD3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
JUN PSMD3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
FLNC PSMD3 25348397 N/A physical interaction ComPPI
PSMA3 PSMD3 25348397 N/A physical interaction ComPPI
PSMD11 PSMD3 25348397 N/A physical interaction ComPPI
PPIL4 PSMD3 25348397 N/A physical interaction ComPPI
GAPDH PSMD3 25348397 N/A physical interaction ComPPI
UBC PSMD3 25348397 N/A physical interaction ComPPI
DLD PSMD3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 PSMD3 25348397 N/A physical interaction ComPPI
PSMA1 PSMD3 25348397 N/A physical interaction ComPPI
PSMA6 PSMD3 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMA5 PSMD3 25348397 N/A physical interaction ComPPI
PSMB9 PSMD3 25348397 N/A physical interaction ComPPI
MYC PSMD3 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NFKBIA PSMD3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CFTR PSMD3 25348397 N/A physical interaction ComPPI
MAPK6 PSMD3 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
PPP2CA PSMD3 25348397 N/A physical interaction ComPPI
PSMD8 PSMD3 25348397 N/A physical interaction ComPPI
SQSTM1 PSMD3 25348397 N/A physical interaction ComPPI
PSMB8 PSMD3 25348397 N/A physical interaction ComPPI
PSMD1 PSMD3 25348397 N/A physical interaction ComPPI
BRCA2 PSMD3 25348397 N/A physical interaction ComPPI
BLM PSMD3 25348397 N/A physical interaction ComPPI
AHR PSMD3 25348397 N/A physical interaction ComPPI
BRF2 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMC5 PSMD3 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HUWE1 PSMD3 25348397 N/A physical interaction ComPPI
RAD23A PSMD3 25348397 N/A physical interaction ComPPI
RPS13 PSMD3 25348397 N/A physical interaction ComPPI
SPR PSMD3 25348397 N/A physical interaction ComPPI
CDK2 PSMD3 25348397 N/A physical interaction ComPPI
PSMC4 PSMD3 25348397 N/A physical interaction ComPPI
NOS2 PSMD3 25348397 N/A physical interaction ComPPI
UBE2A PSMD3 25348397 N/A physical interaction ComPPI
PSMD2 PSMD3 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
VCAM1 PSMD3 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 PSMD3 25348397 N/A physical interaction ComPPI
FLNB PSMD3 25348397 N/A physical interaction ComPPI
MID1 PSMD3 25348397 N/A physical interaction ComPPI
MID2 PSMD3 25348397 N/A physical interaction ComPPI
PRKN PSMD3 25348397 N/A physical interaction ComPPI
TSPYL2 PSMD3 25348397 N/A physical interaction ComPPI
PSMD10 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC5 PSMD3 25348397 N/A physical interaction ComPPI
PSMD4 PSMD3 16990800 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LBR PSMD3 25348397 N/A physical interaction ComPPI
FKBP8 PSMD3 25348397 N/A physical interaction ComPPI
SEM1 PSMD3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SNF8 PSMD3 25348397 N/A physical interaction ComPPI
PSMB5 PSMD3 25348397 N/A physical interaction ComPPI
CRY2 PSMD3 25348397 N/A physical interaction ComPPI
UBQLN1 PSMD3 25348397 N/A physical interaction ComPPI
PSMC1 PSMD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AMFR PSMD3 25348397 N/A physical interaction ComPPI
DERL1 PSMD3 25348397 N/A physical interaction ComPPI
RPS6KB2 PSMD3 25348397 N/A physical interaction ComPPI
BRCA1 PSMD3 25348397 N/A physical interaction ComPPI
MCFD2 PSMD3 25348397 N/A physical interaction ComPPI
PTP4A1 PSMD3 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
PSMB4 PSMD3 25348397 N/A physical interaction ComPPI
BAP1 PSMD3 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB1 PSMD3 25348397 N/A physical interaction ComPPI
PSMB3 PSMD3 25348397 N/A physical interaction ComPPI
PSMB7 PSMD3 25348397 N/A physical interaction ComPPI
PSMA7 PSMD3 25348397 N/A physical interaction ComPPI
PSMA4 PSMD3 25348397 N/A physical interaction ComPPI
CRY1 PSMD3 25348397 N/A physical interaction ComPPI
RNF11 PSMD3 25348397 N/A physical interaction ComPPI
PSMD5 PSMD3 19490896 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GNAI1 PSMD3 25348397 N/A physical interaction ComPPI
IKBKE PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TES PSMD3 25348397 N/A physical interaction ComPPI
AGO2 PSMD3 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PRPF3 PSMD3 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
UCHL5 PSMD3 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HEATR1 PSMD3 25348397 N/A physical interaction ComPPI
L3MBTL1 PSMD3 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
SUGT1 PSMD3 25348397 N/A physical interaction ComPPI
NAA16 PSMD3 25348397 N/A physical interaction ComPPI
HSD17B10 PSMD3 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
ADRM1 PSMD3 24234451 24811749 25348397 association physical interaction,blue native page ComPPI,IntAct
PSMD13 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD12 PSMD3 25348397 N/A physical interaction ComPPI
CYLD PSMD3 25348397 N/A physical interaction ComPPI
CCND2 PSMD3 25348397 N/A physical interaction ComPPI
ATP6V0D1 PSMD3 25348397 N/A physical interaction ComPPI
RPS15A PSMD3 25348397 N/A physical interaction ComPPI
PSMD9 PSMD3 25348397 N/A physical interaction ComPPI
CEP44 PSMD3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBLCP1 PSMD3 25348397 N/A physical interaction ComPPI
PSMC2 PSMD3 25348397 N/A physical interaction ComPPI
POU5F1 PSMD3 25348397 N/A physical interaction ComPPI
PSMD6 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA2 PSMD3 25348397 N/A physical interaction ComPPI
TXNL1 PSMD3 25348397 N/A physical interaction ComPPI
STOML2 PSMD3 25348397 N/A physical interaction ComPPI
AHSA1 PSMD3 25348397 N/A physical interaction ComPPI
FKBPL PSMD3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CCDC92 PSMD3 25348397 N/A physical interaction ComPPI
ACTR3B PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NAA15 PSMD3 25348397 N/A physical interaction ComPPI
PAAF1 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXO25 PSMD3 25348397 N/A physical interaction ComPPI
FBXO6 PSMD3 25348397 N/A physical interaction ComPPI
AMBRA1 PSMD3 25348397 N/A physical interaction ComPPI
PTP4A3 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GFPT1 PSMD3 25348397 N/A physical interaction ComPPI
GH1 PSMD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MTCH1 PSMD3 25348397 N/A physical interaction ComPPI
SPRTN PSMD3 25348397 N/A physical interaction ComPPI
UBE3A PSMD3 25348397 N/A physical interaction ComPPI
ECPAS PSMD3 25348397 N/A physical interaction ComPPI
SEM1 PSMD3 25348397 N/A physical interaction ComPPI
MLF1 PSMD3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
NXF1 PSMD3 25348397 N/A physical interaction ComPPI
PSMD3 RAB5IF 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD3 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD3 USP14 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD3 PSMB6 25348397 N/A physical interaction ComPPI
PSMD3 PSMA8 25348397 N/A physical interaction ComPPI
PSMD3 KCMF1 25348397 N/A physical interaction ComPPI
PSMD3 RPS21 25348397 N/A physical interaction ComPPI
PSMD3 RPS8 25348397 N/A physical interaction ComPPI
PSMD3 STAU1 25348397 N/A physical interaction ComPPI
PSMD3 MOV10 25348397 N/A physical interaction ComPPI
PSMD3 CCDC8 25348397 N/A physical interaction ComPPI
PSMD3 CCDC74B 25348397 N/A physical interaction ComPPI
PSMD3 CCAR2 25348397 N/A physical interaction ComPPI
PSMD3 PSME4 25348397 N/A physical interaction ComPPI
PSMD3 TMOD3 25348397 N/A physical interaction ComPPI
PSMD3 TMEM14B 25348397 N/A physical interaction ComPPI
PSMD3 ZNF746 25348397 N/A physical interaction ComPPI
PSMD3 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMD3 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ZC3H18 PSMD3 24234451 29298432 association chromatin immunoprecipitation assay IntAct
PLEC PSMD3 24234451 30021884 physical association cross-linking study IntAct
TRAF6 PSMD3 14743216 27898060 N/A N/A OmniPath

Visualization