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GENE：PCF11

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PCF11
FullNmae PCF11 cleavage and polyadenylation factor subunit
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30097
EnsembleID ENSG00000165494
Uniprot O94913

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PCF11 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PCF11 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PCF11 GO:0000993,GO:0000993,GO:0003729,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005739,GO:0005849,GO:0005849,GO:0006369,GO:0006369,GO:0006378,GO:0180010

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PCF11 hsa:51585 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PCF11 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PCF11 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PCF11 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PCF11 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
YBX1 PCF11 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PCF11 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PCF11 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PCF11 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000171CD1 PCF11 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 PCF11 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000009A9A2 PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001270D3 PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002B0920 PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001496AE PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000358C16 PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000331800 PCF11 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NUDT21 PCF11 25348397 N/A physical interaction ComPPI
BCAS2 PCF11 25348397 N/A physical interaction ComPPI
SNW1 PCF11 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FIP1L1 PCF11 25348397 N/A physical interaction ComPPI
EMC2 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK3 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 PCF11 25348397 N/A physical interaction ComPPI
RPA1 PCF11 25348397 N/A physical interaction ComPPI
PABPC4 PCF11 25348397 N/A physical interaction ComPPI
CFTR PCF11 25348397 N/A physical interaction ComPPI
PLCB1 PCF11 25348397 N/A physical interaction ComPPI
EWSR1 PCF11 25348397 N/A physical interaction ComPPI
RPA2 PCF11 25348397 N/A physical interaction ComPPI
RPA3 PCF11 25348397 N/A physical interaction ComPPI
PDCD4 PCF11 25348397 N/A physical interaction ComPPI
UBA2 PCF11 25348397 N/A physical interaction ComPPI
RANGAP1 PCF11 25348397 N/A physical interaction ComPPI
USF1 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK8 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDKN2AIP PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CSTF2 PCF11 25348397 N/A physical interaction ComPPI
SRPK2 PCF11 25348397 N/A physical interaction ComPPI
ATF7 PCF11 25348397 N/A physical interaction ComPPI
ALYREF PCF11 25348397 N/A physical interaction ComPPI
PLRG1 PCF11 25348397 N/A physical interaction ComPPI
SRRM1 PCF11 25348397 N/A physical interaction ComPPI
CPSF2 PCF11 25348397 N/A physical interaction ComPPI
WDR33 PCF11 25348397 N/A physical interaction ComPPI
CPSF6 PCF11 25348397 N/A physical interaction ComPPI
TXNDC9 PCF11 25348397 N/A physical interaction ComPPI
AK1 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NXF1 PCF11 25348397 N/A physical interaction ComPPI
MOV10 PCF11 25348397 N/A physical interaction ComPPI
PCF11 RBM27 25348397 N/A physical interaction ComPPI
PCF11 SSU72 25348397 N/A physical interaction ComPPI
HMGN2 PCF11 24234451 30021884 physical association cross-linking study IntAct

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