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GENE：PLA2G12A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLA2G12A
FullNmae phospholipase A2 group XIIA
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18554
EnsembleID ENSG00000123739
Uniprot Q9BZM1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLA2G12A apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLA2G12A GO:0004623,GO:0005509,GO:0005515,GO:0005576,GO:0005576,GO:0005737,GO:0006644,GO:0008150,GO:0016042,GO:0047498,GO:0050482

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLA2G12A hsa:81579 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa00591 Linoleic acid metabolism - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
PLA2G12A hsa:81579 path:hsa04975 Fat digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 PLA2G12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PLA2G12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PLA2G12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PLA2G12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLA2G12A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 PLA2G12A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075AB14 PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 PLA2G12A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000000C73C PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000521626 PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003BBF48 PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 PLA2G12A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B PLA2G12A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000040FA88 PLA2G12A 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000070B1D PLA2G12A 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
YWHAG PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPS15 PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RB1 PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPS6 PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DVL2 PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EPB41L3 PLA2G12A 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MEF2C PLA2G12A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRIM25 PLA2G12A 25348397 N/A physical interaction ComPPI
PLA2G12A TMEM37 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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