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GENE：PLA2G12B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PLA2G12B
FullNmae phospholipase A2 group XIIB
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18555
EnsembleID ENSG00000138308
Uniprot Q9BX93

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PLA2G12B apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PLA2G12B GO:0004623,GO:0005509,GO:0005576,GO:0006644,GO:0016042,GO:0042632,GO:0050482,GO:0070328

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PLA2G12B hsa:84647 path:hsa00564 Glycerophospholipid metabolism - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa00565 Ether lipid metabolism - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa00591 Linoleic acid metabolism - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa00592 alpha-Linolenic acid metabolism - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa04270 Vascular smooth muscle contraction - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa04972 Pancreatic secretion - Homo sapiens (human)
PLA2G12B hsa:84647 path:hsa04975 Fat digestion and absorption - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PLA2G12B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 PLA2G12B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 PLA2G12B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PLA2G12B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PLA2G12B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
ADAMTS1 PLA2G12B 25348397 N/A physical interaction ComPPI
GLG1 PLA2G12B 25348397 N/A physical interaction ComPPI

Visualization










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