GENE:PPP3R2
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | PPP3R2 |
FullNmae | protein phosphatase 3 regulatory subunit B, beta |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:9318 |
EnsembleID | ENSG00000188386 |
Uniprot | Q96LZ3 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
PPP3R2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PPP3R2 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
PPP3R2 | GO:0005509,GO:0005515,GO:0005739,GO:0005829,GO:0005955,GO:0005955,GO:0006470,GO:0007341,GO:0008287,GO:0008597,GO:0008597,GO:0019902,GO:0070886,GO:0097226,GO:0097720,GO:1905665,GO:1905949 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
PPP3R2 | hsa:5535 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04022 | cGMP-PKG signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04114 | Oocyte meiosis - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04218 | Cellular senescence - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04360 | Axon guidance - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04370 | VEGF signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04625 | C-type lectin receptor signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04650 | Natural killer cell mediated cytotoxicity - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04658 | Th1 and Th2 cell differentiation - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04659 | Th17 cell differentiation - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04660 | T cell receptor signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04662 | B cell receptor signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04720 | Long-term potentiation - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04724 | Glutamatergic synapse - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04921 | Oxytocin signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04922 | Glucagon signaling pathway - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa04924 | Renin secretion - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05014 | Amyotrophic lateral sclerosis - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05020 | Prion disease - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05031 | Amphetamine addiction - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05152 | Tuberculosis - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05163 | Human cytomegalovirus infection - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05166 | Human T-cell leukemia virus 1 infection - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05167 | Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05170 | Human immunodeficiency virus 1 infection - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human) |
PPP3R2 | hsa:5535 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
E2F4 | PPP3R2 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CCND1 | PPP3R2 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | TBC1D10C | 14525934 17230191 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
PPP3R2 | CD14 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
PPP3R2 | TFCP2 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
PPP3R2 | APC | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | AURKA | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | BUB1 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | DLC1 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | FBXW7 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | MSH2 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | PTPN12 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | PTPRJ | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |
PPP3R2 | SMAD4 | 24234451 24412244 25348397 | physical association | two hybrid,two hybrid array | ComPPI,IntAct |