Gene Information gene info

GENE:PPP3R2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPP3R2
FullNmae protein phosphatase 3 regulatory subunit B, beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9318
EnsembleID ENSG00000188386
Uniprot Q96LZ3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPP3R2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PPP3R2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPP3R2 GO:0005509,GO:0005515,GO:0005739,GO:0005829,GO:0005955,GO:0005955,GO:0006470,GO:0007341,GO:0008287,GO:0008597,GO:0008597,GO:0019902,GO:0070886,GO:0097226,GO:0097720,GO:1905665,GO:1905949

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPP3R2 hsa:5535 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04114 Oocyte meiosis - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04218 Cellular senescence - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04360 Axon guidance - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04370 VEGF signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04720 Long-term potentiation - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa04924 Renin secretion - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05020 Prion disease - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05031 Amphetamine addiction - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05152 Tuberculosis - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer - Homo sapiens (human)
PPP3R2 hsa:5535 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PPP3R2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PPP3R2 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00004B4B85 PPP3R2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CCND1 PPP3R2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 TBC1D10C 14525934 17230191 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PPP3R2 CD14 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PPP3R2 TFCP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PPP3R2 APC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 AURKA 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 BUB1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 DLC1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 MSH2 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 PTPN12 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 PTPRJ 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
PPP3R2 SMAD4 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct

Visualization