Gene Information gene info

GENE:PRKAR1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRKAR1B
FullNmae protein kinase cAMP-dependent type I regulatory subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9390
EnsembleID ENSG00000188191
Uniprot P31321

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRKAR1B apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRKAR1B GO:0004862,GO:0005515,GO:0005771,GO:0005829,GO:0005829,GO:0005886,GO:0005952,GO:0006468,GO:0007611,GO:0008603,GO:0008603,GO:0030552,GO:0034236,GO:0097546,GO:0098685,GO:0098686,GO:0098693,GO:0098794,GO:0098978,GO:1900273,GO:1903367,GO:2000463,GO:2000480

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRKAR1B hsa:5575 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 PRKAR1B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PRKAR1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
UBE2I PRKAR1B 20936779 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SNW1 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPKOW PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBX8 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STK16 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAA2 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COX5B PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDC42 PRKAR1B 25348397 N/A two hybrid ComPPI
QRICH1 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BAG3 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDKN1A PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GOLGA1 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLE4 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR2B PRKAR1B 25348397 N/A physical interaction ComPPI
KIF5B PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RABGGTB PRKAR1B 25348397 N/A physical interaction ComPPI
SMAD4 PRKAR1B 14525934 14966294 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKACB PRKAR1B 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GNL3L PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R9A PRKAR1B 12052877 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SYTL4 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMAD3 PRKAR1B 14525934 14966294 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PRKACA PRKAR1B 23455922 24234451 24605759 25348397 phosphorylation reaction,association,physical association physical interaction,two hybrid array,protein kinase assay,tandem affinity purification,two hybrid prey pooling approach ComPPI,IntAct
VAPA PRKAR1B 25348397 N/A physical interaction ComPPI
GSK3B PRKAR1B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
THRA PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CUL3 PRKAR1B 25348397 N/A physical interaction ComPPI
PRKAR1A PRKAR1B 12634056 14525934 24234451 25348397 8407966 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
PIK3R3 PRKAR1B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WRN PRKAR1B 12067711 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
MYC PRKAR1B 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
AKAP1 PRKAR1B 12634056 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PRKAR1B EGFR 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
PRKAR1B WNK1 25348397 N/A physical interaction ComPPI
PRKAR1B DUS3L 25348397 N/A physical interaction ComPPI
PRKAR1B EEF2K 25348397 N/A physical interaction ComPPI
PRKAR1B MLF1 25348397 N/A physical interaction ComPPI
PRKAR1B NAPG 25348397 N/A physical interaction ComPPI
PRKAR1B AP2M1 25348397 N/A physical interaction ComPPI
PRKAR1B DCLRE1C 25348397 N/A physical interaction ComPPI
PRKAR1B VAPB 25348397 N/A physical interaction ComPPI
PRKAR1B XPO1 25348397 N/A physical interaction ComPPI
PRKAR1B PRPSAP2 25348397 N/A physical interaction ComPPI
PRKAR1B SKP2 25348397 N/A physical interaction ComPPI
PRKAR1B PRKACG 25348397 N/A physical interaction ComPPI
PRKAR1B ETFB 25348397 N/A physical interaction ComPPI
PRKAR1B TRIM25 25348397 N/A physical interaction ComPPI
PRKAR1B HNRNPL 25348397 N/A physical interaction ComPPI
PRKAR1B SHC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B PRPF18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B NXF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B L3MBTL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B SMG9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B TASOR2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B ZBTB16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B UACA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B SH2D4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B RARG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B CDC37 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRKAR1B GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CALU PRKAR1B 25348397 N/A physical interaction ComPPI
H1-0 PRKAR1B 24234451 30021884 physical association cross-linking study IntAct

Visualization