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GENE：PSMB3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSMB3
FullNmae proteasome 20S subunit beta 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9540
EnsembleID ENSG00000277791
Uniprot P49720

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSMB3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSMB3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSMB3 GO:0000502,GO:0000502,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005839,GO:0005839,GO:0010498,GO:0019774,GO:0019774,GO:0043161,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSMB3 hsa:5691 path:hsa03050 Proteasome - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05010 Alzheimer disease - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05012 Parkinson disease - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05016 Huntington disease - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05020 Prion disease - Homo sapiens (human)
PSMB3 hsa:5691 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PSMB3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSMB3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PSMB3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC PSMB3 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 PSMB3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 PSMB3 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PSMA4 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMA4 25361965 interaction type N/A PTMCode2
PSMB3 PSMA5 25361965 interaction type N/A PTMCode2
PSMA5 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 RPS27A 25361965 interaction type N/A PTMCode2
RPS27A PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMA1 25361965 interaction type N/A PTMCode2
PSMA1 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMB10 25361965 interaction type N/A PTMCode2
PSMB10 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMA7 25361965 interaction type N/A PTMCode2
PSMA7 PSMB3 25361965 interaction type N/A PTMCode2
PSMA3 PSMB3 25361965 interaction type N/A PTMCode2
PSMB3 PSMA3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EIF1B PSMB3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB10 PSMB3 14733938 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GET3 PSMB3 25348397 N/A physical interaction ComPPI
BAG3 PSMB3 25348397 N/A physical interaction ComPPI
SNRPA1 PSMB3 25348397 N/A physical interaction ComPPI
PSMC3 PSMB3 25348397 N/A physical interaction ComPPI
PSMC6 PSMB3 25348397 N/A physical interaction ComPPI
TRAF6 PSMB3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB2 PSMB3 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB4 PSMB3 25348397 N/A physical interaction ComPPI
PSMB1 PSMB3 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB3 PLK1 11205743 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PSMB3 PSMB5 14525934 14733938 17948026 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB3 PSMB7 14525934 14733938 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PSMB3 DSTYK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 VHL 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 UCHL5 18922472 19490896 19615732 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 MYC 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PSMB3 INSIG2 25348397 N/A physical interaction ComPPI
PSMB3 PSMA2 15887188 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 RAD23A 25348397 N/A physical interaction ComPPI
PSMB3 FKBP8 25348397 N/A physical interaction ComPPI
PSMB3 CUL1 25348397 N/A physical interaction ComPPI
PSMB3 POMP 17948026 24234451 25348397 25416956 physical association two hybrid,physical interaction,mammalian protein protein interaction trap ComPPI,IntAct
PSMB3 PSMB6 25348397 N/A physical interaction ComPPI
PSMB3 PSMB8 25348397 N/A physical interaction ComPPI
PSMB3 PSMA1 12376572 24234451 25348397 25599644 29568061 association,physical association affinity chromatography technology,pull down,x-ray crystallography,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PSMB3 PSMA3 25348397 N/A physical interaction ComPPI
PSMB3 PSMA4 25348397 N/A physical interaction ComPPI
PSMB3 PSMA5 25348397 N/A physical interaction ComPPI
PSMB3 PSMA6 17948026 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 PSMA7 17948026 24234451 25348397 association,physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PSMB3 PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 PSMC1 25348397 N/A physical interaction ComPPI
PSMB3 PSMC4 25348397 N/A physical interaction ComPPI
PSMB3 PSMC2 25348397 N/A physical interaction ComPPI
PSMB3 PSMC5 25348397 N/A physical interaction ComPPI
PSMB3 PSMD11 25348397 N/A physical interaction ComPPI
PSMB3 PSMD13 25348397 N/A physical interaction ComPPI
PSMB3 PSMD7 25348397 N/A physical interaction ComPPI
PSMB3 PSMD1 25348397 N/A physical interaction ComPPI
PSMB3 PSMD2 25348397 N/A physical interaction ComPPI
PSMB3 PSMD8 25348397 N/A physical interaction ComPPI
PSMB3 PSMD3 25348397 N/A physical interaction ComPPI
PSMB3 PSMD14 25348397 N/A physical interaction ComPPI
PSMB3 PSMD12 25348397 N/A physical interaction ComPPI
PSMB3 PSME2 25348397 N/A physical interaction ComPPI
PSMB3 PSMD4 25348397 N/A physical interaction ComPPI
PSMB3 PSME3 25348397 N/A physical interaction ComPPI
PSMB3 PSME1 25348397 N/A physical interaction ComPPI
PSMB3 PSMA8 25348397 N/A physical interaction ComPPI
PSMB3 SF3A1 25348397 N/A physical interaction ComPPI
PSMB3 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PSMB3 IQCB1 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMB3 CFTR 25348397 N/A physical interaction ComPPI
PSMB3 PRKN 25348397 N/A physical interaction ComPPI
PSMB3 PRMT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMB3 MPZ 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PSMB3 TP53 25348397 N/A physical interaction ComPPI
PSMB3 HECW2 25348397 N/A physical interaction ComPPI
PSMB3 AP3M1 25348397 N/A physical interaction ComPPI
PSMB3 CAST 25348397 N/A physical interaction ComPPI
PSMB3 EPB41L1 25348397 N/A physical interaction ComPPI
PSMB3 KIF5B 25348397 N/A physical interaction ComPPI
PSMB3 SART3 25348397 N/A physical interaction ComPPI
PSMB3 PSME4 25348397 N/A physical interaction ComPPI
PSMB3 PYCR3 25348397 N/A physical interaction ComPPI
PSMB3 PSMG3 25348397 N/A physical interaction ComPPI
PSMB3 TRIM27 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMB3 AMFR 25348397 N/A physical interaction ComPPI
PSMB3 SYVN1 25348397 N/A physical interaction ComPPI
PSMB3 ABCE1 25348397 N/A physical interaction ComPPI
PSMB3 PSMB9 25348397 N/A physical interaction ComPPI
PSMB3 AMBRA1 25348397 N/A physical interaction ComPPI
PSMB3 CAPZA1 25348397 N/A physical interaction ComPPI
PSMB3 CPSF2 25348397 N/A physical interaction ComPPI
PSMB3 ELP6 25348397 N/A physical interaction ComPPI
PSMB3 HEATR1 25348397 N/A physical interaction ComPPI
PSMB3 KDM2A 25348397 N/A physical interaction ComPPI
PSMB3 ADRM1 25348397 N/A physical interaction ComPPI
PSMB3 PSMD5 25348397 N/A physical interaction ComPPI
PSMB3 UBA2 25348397 N/A physical interaction ComPPI
PSMB3 PSMG2 25348397 N/A physical interaction ComPPI
PSMB3 MCM2 25348397 N/A physical interaction ComPPI
PSMB3 FBXO7 25348397 N/A physical interaction ComPPI
PSMB3 AKIRIN2 25348397 N/A physical interaction ComPPI
PSMB3 OSER1 25348397 N/A physical interaction ComPPI
PSMB3 RNF181 25348397 N/A physical interaction ComPPI
PSMB3 PSMF1 25348397 N/A physical interaction ComPPI
PSMB3 PSMG4 25348397 N/A physical interaction ComPPI
PSMB3 PSMG1 25348397 N/A physical interaction ComPPI
PSMB3 FANCB 25348397 N/A physical interaction ComPPI
PSMB3 AKIRIN1 25348397 N/A physical interaction ComPPI
PSMB3 PSME3IP1 25348397 N/A physical interaction ComPPI
PSMB3 KEAP1 25348397 N/A physical interaction ComPPI
PSMB3 EIF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 FTSJ1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 HLA-B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 PRKAB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 YWHAZ 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
PSMB3 EHMT2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB3 L3MBTL1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB3 SKP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
PSMB3 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB3 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB3 H3C1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TRAF2 PSMB3 24234451 30561431 association virotrap IntAct

Visualization










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