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GENE：PSME4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PSME4
FullNmae proteasome activator subunit 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20635
EnsembleID ENSG00000068878
Uniprot Q14997

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PSME4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PSME4 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PSME4 GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0005829,GO:0006281,GO:0006974,GO:0010499,GO:0010499,GO:0016504,GO:0016504,GO:0016607,GO:0035092,GO:0070577,GO:0070577,GO:0070628,GO:1990111,GO:1990111

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PSME4 hsa:23198 path:hsa03050 Proteasome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PSME4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 PSME4 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PSME4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PSME4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 PSME4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PSME4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PSME4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PSME4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PSME4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PSME4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 PSME4 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000338542 PSME4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000122ED0 PSME4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 PSME4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000032FC1A PSME4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 PSME4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075BEA7 PSME4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA PSME4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 PSME4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PSME4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 PSME4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PSMC6 PSME4 18845680 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMD14 PSME4 25348397 N/A physical interaction ComPPI
PSMB2 PSME4 25348397 N/A physical interaction ComPPI
H4C1 PSME4 23706739 24234451 25348397 27898060 physical association pull down ComPPI,IntAct,OmniPath
JUN PSME4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 PSME4 25348397 N/A physical interaction ComPPI
PSMA3 PSME4 25348397 N/A physical interaction ComPPI
NTRK1 PSME4 25348397 N/A physical interaction ComPPI
PSMA1 PSME4 25348397 N/A physical interaction ComPPI
PSMA5 PSME4 25348397 N/A physical interaction ComPPI
PSMB9 PSME4 25348397 N/A physical interaction ComPPI
MYC PSME4 17314511 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RUFY1 PSME4 25348397 N/A physical interaction ComPPI
RAD23A PSME4 25348397 N/A physical interaction ComPPI
FDPS PSME4 25348397 N/A physical interaction ComPPI
DDX3X PSME4 25348397 N/A physical interaction ComPPI
SART3 PSME4 25348397 N/A physical interaction ComPPI
MTNR1A PSME4 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
AMFR PSME4 25348397 N/A physical interaction ComPPI
PSMB4 PSME4 25348397 N/A physical interaction ComPPI
PSMB1 PSME4 25348397 N/A physical interaction ComPPI
PSMB3 PSME4 25348397 N/A physical interaction ComPPI
PSMB7 PSME4 25348397 N/A physical interaction ComPPI
PSMA7 PSME4 25348397 N/A physical interaction ComPPI
PSMA4 PSME4 25348397 N/A physical interaction ComPPI
CALCOCO2 PSME4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
A1BG PSME4 25348397 N/A physical interaction ComPPI
PSMD3 PSME4 25348397 N/A physical interaction ComPPI
PSMB6 PSME4 25348397 N/A physical interaction ComPPI
ARHGEF10 PSME4 25348397 N/A physical interaction ComPPI
TTI1 PSME4 25348397 N/A physical interaction ComPPI

Source Target Pmid Interactiontype Methods Database
URS00009B3047 PSME4 27087310 direct interaction,inhibition N/A NPInter
URS00009B373C PSME4 27087310 direct interaction,inhibition N/A NPInter

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