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GENE：SAP18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SAP18
FullNmae Sin3A associated protein 18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10530
EnsembleID ENSG00000150459
Uniprot O00422

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SAP18 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SAP18 GO:0000118,GO:0000381,GO:0000381,GO:0003714,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0006357,GO:0006397,GO:0008134,GO:0008380,GO:0016604,GO:0016607,GO:0043065,GO:0045892,GO:0048025,GO:0061574

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SAP18 hsa:10284 path:hsa03013 Nucleocytoplasmic transport - Homo sapiens (human)
SAP18 hsa:10284 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CDK2 SAP18 21319273 23180781 physical association anti tag coimmunoprecipitation InnateDB
SUZ12 SAP18 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 SAP18 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
BMI1 SAP18 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
SUFU SAP18 11960000 14611647 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 SAP18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SAP18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC SAP18 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D SAP18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE SAP18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D SAP18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001012BC SAP18 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 SAP18 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GLI1 SAP18 25361965 interaction type N/A PTMCode2
SAP18 GLI1 25361965 interaction type N/A PTMCode2
SAP18 GLI3 25361965 interaction type N/A PTMCode2
GLI3 SAP18 25361965 interaction type N/A PTMCode2
HDAC8 SAP18 25361965 interaction type N/A PTMCode2
SAP18 HDAC8 25361965 interaction type N/A PTMCode2
RNPS1 SAP18 25361965 interaction type N/A PTMCode2
SAP18 RNPS1 25361965 interaction type N/A PTMCode2
HDAC3 SAP18 25361965 interaction type N/A PTMCode2
SAP18 HDAC3 25361965 interaction type N/A PTMCode2
ACIN1 SAP18 25361965 interaction type N/A PTMCode2
SAP18 ACIN1 25361965 interaction type N/A PTMCode2
SUFU SAP18 25361965 interaction type N/A PTMCode2
SAP18 SUFU 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC5L SAP18 25348397 N/A physical interaction ComPPI
HNRNPC SAP18 25348397 N/A physical interaction ComPPI
DES SAP18 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DEF6 SAP18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAP18 IKZF1 10357820 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SAP18 SUFU 11960000 14525934 14611647 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
SAP18 TADA3 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SAP18 POLE2 11872158 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
SAP18 RPS3A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SAP18 NOL12 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SAP18 SIN3A 11960000 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
SAP18 RPN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 RGS10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 DDOST 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 YARS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 KIFBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 DDX3X 25348397 N/A physical interaction ComPPI
SAP18 NSF 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 EIF3E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 ATP5MG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 ARMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 GLI1 25348397 N/A physical interaction ComPPI
SAP18 OSBPL10 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 RNPS1 25348397 N/A anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
SAP18 ACIN1 25348397 N/A anti tag coimmunoprecipitation,pull down,physical interaction ComPPI
SAP18 SRRM1 25348397 N/A physical interaction ComPPI
SAP18 EMD 25348397 N/A physical interaction ComPPI
SAP18 RBM39 22365833 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SAP18 PNN 22388736 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 CDK2 25348397 N/A physical interaction ComPPI
SAP18 GRK5 25348397 N/A physical interaction ComPPI
SAP18 SMARCA5 25348397 N/A physical interaction ComPPI
SAP18 SMARCC2 25348397 N/A physical interaction ComPPI
SAP18 SMARCB1 24234451 25348397 30108113 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SAP18 DDX21 25348397 N/A physical interaction ComPPI
SAP18 SRSF11 25348397 N/A physical interaction ComPPI
SAP18 SRSF1 25348397 N/A physical interaction ComPPI
SAP18 SRSF3 25348397 N/A physical interaction ComPPI
SAP18 SRSF5 25348397 N/A physical interaction ComPPI
SAP18 SRSF7 25348397 N/A physical interaction ComPPI
SAP18 SNRPD2 25348397 N/A physical interaction ComPPI
SAP18 SART1 25348397 N/A physical interaction ComPPI
SAP18 SUPT16H 25348397 N/A physical interaction ComPPI
SAP18 SMU1 25348397 N/A physical interaction ComPPI
SAP18 SNU13 25348397 N/A physical interaction ComPPI
SAP18 PRPF6 25348397 N/A physical interaction ComPPI
SAP18 IK 25348397 N/A physical interaction ComPPI
SAP18 U2AF1L5 25348397 N/A physical interaction ComPPI
SAP18 U2AF1 25348397 N/A physical interaction ComPPI
SAP18 PRPF40A 25348397 N/A physical interaction ComPPI
SAP18 U2AF2 25348397 N/A physical interaction ComPPI
SAP18 SRRT 25348397 N/A physical interaction ComPPI
SAP18 SSRP1 25348397 N/A physical interaction ComPPI
SAP18 HNRNPU 25348397 N/A physical interaction ComPPI
SAP18 MATR3 25348397 N/A physical interaction ComPPI
SAP18 SAFB 25348397 N/A physical interaction ComPPI
SAP18 SEPTIN2 25348397 N/A physical interaction ComPPI
SAP18 SEPTIN7 25348397 N/A physical interaction ComPPI
SAP18 PHGDH 25348397 N/A physical interaction ComPPI
SAP18 SRSF10 25348397 N/A physical interaction ComPPI
SAP18 WDR18 25348397 N/A physical interaction ComPPI
SAP18 NFIA 25348397 N/A physical interaction ComPPI
SAP18 NCSTN 25348397 N/A physical interaction ComPPI
SAP18 PSAP 25348397 N/A physical interaction ComPPI
SAP18 S100A9 25348397 N/A physical interaction ComPPI
SAP18 TRIM55 25348397 N/A physical interaction ComPPI
SAP18 TFPI 25348397 N/A physical interaction ComPPI
SAP18 THRAP3 25348397 N/A physical interaction ComPPI
SAP18 GTF3C1 25348397 N/A physical interaction ComPPI
SAP18 SSR3 25348397 N/A physical interaction ComPPI
SAP18 PSIP1 25348397 N/A physical interaction ComPPI
SAP18 TRA2A 25348397 N/A physical interaction ComPPI
SAP18 RBM14 25348397 N/A physical interaction ComPPI
SAP18 EBNA1BP2 25348397 N/A physical interaction ComPPI
SAP18 TPR 25348397 N/A physical interaction ComPPI
SAP18 MYO1C 25348397 N/A physical interaction ComPPI
SAP18 ADNP 25348397 N/A physical interaction ComPPI
SAP18 SURF4 25348397 N/A physical interaction ComPPI
SAP18 VTN 25348397 N/A physical interaction ComPPI
SAP18 NOLC1 25348397 N/A physical interaction ComPPI
SAP18 EIF4A3 23084401 24234451 25348397 association,physical association anti tag coimmunoprecipitation,molecular sieving,physical interaction ComPPI,IntAct
SAP18 MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 VCP 25348397 N/A physical interaction ComPPI
SAP18 CSNK2A2 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SAP18 INCA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SAP18 SUZ12 25348397 N/A physical interaction ComPPI
SAP18 RNF2 25348397 N/A physical interaction ComPPI
SAP18 BMI1 25348397 N/A physical interaction ComPPI
SAP18 LUZP4 25348397 N/A physical interaction ComPPI
SAP18 EPB41L3 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 ZMYND11 25348397 N/A physical interaction ComPPI
SAP18 SFN 25348397 N/A physical interaction ComPPI
SAP18 IFI16 25348397 N/A physical interaction ComPPI
SAP18 HNRNPD 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 CCDC22 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 RNASEH2B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SAP18 USP37 25348397 N/A physical interaction ComPPI
SAP18 PCGF1 25348397 N/A physical interaction ComPPI
SAP18 TSC22D2 25348397 N/A physical interaction ComPPI
SAP18 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAP18 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAP18 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAP18 PARK7 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAP18 VDAC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
SAP18 LMNA 25348397 N/A physical interaction ComPPI
SAP18 HDAC1 14525934 24234451 25348397 9150135 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down ComPPI,HPRD,IntAct
SAP18 SEPTIN6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 YWHAG 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 MACF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 NCLN 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 DNAAF5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 DNAJA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 HSPB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 PCBP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 GLS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 CLPP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 NUP93 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 ARMC6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 GSPT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 ATXN10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 YWHAB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 MAT2A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SAP18 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SAP18 DDX41 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
SAP18 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SAP18 HSCB 24234451 24606901 25348397 physical association two hybrid ComPPI,IntAct
SAP18 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SAP18 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
DDX19B SAP18 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NCBP3 SAP18 24234451 26382858 association pull down IntAct
SAP18 HPS5 24234451 30021884 physical association cross-linking study IntAct
SAP18 GNPTAB 24234451 30021884 physical association cross-linking study IntAct
SAP18 AARS1 24234451 30021884 physical association cross-linking study IntAct
SAP18 KIF20B 24234451 30021884 physical association cross-linking study IntAct
L1TD1 SAP18 24234451 25702638 association anti bait coimmunoprecipitation IntAct
SAP18 HES4 17623094 27898060 N/A N/A OmniPath
SUFU SAP18 1196 11960000 14611647 27898060 stimulant N/A OmniPath

Visualization










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