Gene Information gene info

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GENE：ZFYVE16

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZFYVE16
FullNmae zinc finger FYVE-type containing 16
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20756
EnsembleID ENSG00000039319
Uniprot Q7Z3T8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZFYVE16 lysosomal_cd 36341760 220 lysosome-dependent cell death genes. retulator signature
ZFYVE16 lysosomal_cd 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
ZFYVE16 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZFYVE16 GO:0005515,GO:0005545,GO:0005547,GO:0005769,GO:0005829,GO:0006622,GO:0006622,GO:0007165,GO:0016050,GO:0016197,GO:0016197,GO:0030100,GO:0031901,GO:0031901,GO:0043231,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZFYVE16 hsa:9765 path:hsa04144 Endocytosis - Homo sapiens (human)
ZFYVE16 hsa:9765 path:hsa04350 TGF-beta signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMAD4 ZFYVE16 17272273 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZFYVE16 ACVR1B 17272273 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZFYVE16 TGFBR1 17272273 23180781 physical association anti tag coimmunoprecipitation InnateDB
ZFYVE16 BMPR1A 17272273 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ZFYVE16 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 ZFYVE16 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ZFYVE16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZFYVE16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZFYVE16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ZFYVE16 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ZFYVE16 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D ZFYVE16 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 ZFYVE16 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 ZFYVE16 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 ZFYVE16 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ZFYVE16 TOM1L2 25361965 interaction type N/A PTMCode2
TOM1L2 ZFYVE16 25361965 interaction type N/A PTMCode2
ZFYVE16 TOM1 25361965 interaction type N/A PTMCode2
TOM1 ZFYVE16 25361965 interaction type N/A PTMCode2
EEA1 ZFYVE16 25361965 interaction type N/A PTMCode2
ZFYVE16 EEA1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC ZFYVE16 25348397 N/A physical interaction ComPPI
PSMC3 ZFYVE16 25348397 N/A physical interaction ComPPI
EGLN3 ZFYVE16 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
CDH1 ZFYVE16 25348397 N/A physical interaction ComPPI
PPP1CA ZFYVE16 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EEA1 ZFYVE16 14613930 24234451 25348397 29568061 association,physical association cosedimentation through density gradient,in vitro,proximity-dependent biotin identification ComPPI,IntAct
RAB9A ZFYVE16 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RNF11 ZFYVE16 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TGOLN2 ZFYVE16 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 ZFYVE16 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ZFYVE16 TOM1 14613930 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,cosedimentation through density gradient,pull down,physical interaction ComPPI,IntAct
ZFYVE16 APP 25348397 N/A physical interaction ComPPI
ZFYVE16 MED4 25348397 N/A physical interaction ComPPI
ZFYVE16 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PTPN23 ZFYVE16 25348397 N/A physical interaction ComPPI
SPTAN1 ZFYVE16 24234451 30021884 physical association cross-linking study IntAct
ZFYVE16 TGFBR1 17272273 27898060 N/A N/A OmniPath

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