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GENE：BRMS1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BRMS1
FullNmae BRMS1 transcriptional repressor and anoikis regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17262
EnsembleID ENSG00000174744
Uniprot Q9HCU9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BRMS1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BRMS1 anoikis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
BRMS1 GO:0000122,GO:0000122,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0006915,GO:0016580,GO:0030336,GO:0030512,GO:0032088,GO:0042826,GO:0042981,GO:0045892,GO:0051059,GO:0070822,GO:0090312,GO:1902455,GO:1902459,GO:2000210

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 BRMS1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 BRMS1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 BRMS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BRMS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 BRMS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS BRMS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 BRMS1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EBD4B BRMS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 BRMS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 BRMS1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000134ADC BRMS1 25416803 27501413 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 BRMS1 22135298 phosphorylation N/A PhosphoSite
HDAC3 BRMS1 25361965 interaction type N/A PTMCode2
BRMS1 HDAC3 25361965 interaction type N/A PTMCode2
NFKB1 BRMS1 25361965 interaction type N/A PTMCode2
BRMS1 NFKB1 25361965 interaction type N/A PTMCode2
RELA BRMS1 25361965 interaction type N/A PTMCode2
BRMS1 RELA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NMI BRMS1 16919237 24234451 25348397 25416956 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMARCE1 BRMS1 16919237 24234451 25348397 25416956 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vivo ComPPI,IntAct
HSPA8 BRMS1 16919237 24234451 25348397 association pull down ComPPI,IntAct
CDC42 BRMS1 25348397 N/A two hybrid ComPPI
KPNA5 BRMS1 16919237 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2D1 BRMS1 25348397 N/A physical interaction ComPPI
BRMS1 ING1 25348397 N/A physical interaction,in vivo ComPPI
BRMS1 RBBP4 25348397 N/A physical interaction,in vivo ComPPI
BRMS1 SAP30 25348397 N/A physical interaction,in vivo ComPPI
BRMS1 HDAC2 16919237 21258344 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
BRMS1 SIN3A 14581478 15451426 21258344 23390556 24234451 25348397 27898060 association anti bait coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct,OmniPath
BRMS1 BRMS1L 25348397 N/A physical interaction,in vivo ComPPI
BRMS1 EEF1A1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRMS1 GOLGB1 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRMS1 LRIF1 25348397 N/A two hybrid,physical interaction ComPPI
BRMS1 PFDN5 25348397 N/A two hybrid,in vivo ComPPI
BRMS1 DNAJB6 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction,in vivo ComPPI,IntAct
BRMS1 TAF1 16919237 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BRMS1 SMTN 16919237 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BRMS1 DNAJB1 25348397 N/A in vivo ComPPI
BRMS1 HSP90AA1 16919237 24234451 25348397 association pull down,physical interaction,in vivo ComPPI,IntAct
BRMS1 HSPA4 25348397 N/A physical interaction,in vivo ComPPI
BRMS1 HDAC4 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
BRMS1 HDAC5 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
BRMS1 HDAC6 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,in vivo ComPPI,IntAct
BRMS1 EEF1A1P5 25348397 N/A physical interaction ComPPI
BRMS1 HDAC3 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BRMS1 RELA 25348397 N/A physical interaction ComPPI
BRMS1 NFKB1 25348397 N/A physical interaction ComPPI
BRMS1 HDAC1 16919237 21258344 23752268 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BRMS1 SAP25 25348397 N/A physical interaction ComPPI
BRMS1 ARID4A 14581478 16919237 18211900 24234451 25348397 27898060 physical association two hybrid,physical interaction ComPPI,IntAct,OmniPath
BRMS1 SUDS3 16919237 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
BRMS1 HSP90AA2P 25348397 N/A physical interaction ComPPI
BRMS1 APP 25348397 N/A physical interaction ComPPI
BRMS1 CEP70 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BRMS1 SNX6 20830743 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BRMS1 E2F1 25348397 N/A physical interaction ComPPI
BRMS1 SIN3B 25348397 N/A physical interaction ComPPI
BRMS1 RBBP7 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1 EP300 23269275 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BRMS1 CUL3 25348397 N/A physical interaction ComPPI
BRMS1 SPOP 22085717 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BRMS1 MXD1 25348397 N/A physical interaction ComPPI
BRMS1 PRPS1 25348397 N/A physical interaction ComPPI
BRMS1 CREBBP 25348397 N/A physical interaction ComPPI
BRMS1 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 BEX2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 DIRAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 IL13RA2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 KLK9 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 LYPD3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 MRC2 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 PSMC3IP 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 THRSP 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BRMS1 AP5Z1 25348397 N/A physical interaction ComPPI
BRMS1 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1 FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
BRMS1 GATAD1 25348397 N/A physical interaction ComPPI
BRMS1 SINHCAF 25348397 N/A physical interaction ComPPI
BRMS1 ING2 25348397 N/A physical interaction ComPPI
BRMS1 MXD3 25348397 N/A physical interaction ComPPI
BRMS1 MBIP 25348397 N/A physical interaction ComPPI
BRMS1 ZNF704 25348397 N/A physical interaction ComPPI
BRMS1 POLR2E 25348397 N/A physical interaction ComPPI
BRMS1 CSNK2A1 25348397 N/A physical interaction ComPPI
BRMS1 YWHAE 25348397 N/A physical interaction ComPPI
BRMS1 HNRNPL 25348397 N/A physical interaction ComPPI
BRMS1 PHB 25348397 N/A coimmunoprecipitation,physical interaction ComPPI
BRMS1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
BRMS1 MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNAI1 BRMS1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
METTL3 BRMS1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
WTAP BRMS1 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 BRMS1 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization










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