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GENE：XIAP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol XIAP
FullNmae X-linked inhibitor of apoptosis
LocusType gene with protein product
Status Approved
HGNC_id HGNC:592
EnsembleID ENSG00000101966
Uniprot P98170

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
XIAP necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
XIAP necroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
XIAP mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
XIAP mitotic_cd 17613533 Immunoprecipitation studies indicate that XAF1 binds to XIAP, cIAP1, cIAP2, Livin, TsIAP, and NAIP but not Survivin, an IAP that prevents mitotic catastrophe and in which antiapoptotic activity is exerted through direct XIAP interaction and stabilization. retulator signature
XIAP cuproptosis 39198750 XIAP, the target of triptolide, played a role in cuproptosis by regulating COMMD1. retulator signature
XIAP cuproptosis 38408075 We retrieved 21 genes involved in Cuproptosis from the literature, including CDKN2A, DLD, DLAT, FDX1, GLS, LIAS, LIPT1, MTF1, PDHA1, and PDHB, ATB7B, CUTC, GRX1, MT1A, MT2A, MT3, XIAP, ATM, PRNP, P53, and SP1. genes involved in Cuproptosis
XIAP cuproptosis 38408075 ATP7B and GRX1 excrete excess copper ions out of the mitochondria. CUTC directly binds Cu2+ while XIAP passivates and hydrolyzes caspase after binding Cu2+ to inhibit Cuproptosis. Inhibitor
XIAP cuproptosis 35964468 Cuproptosis-related gene sets were obtained from a previous study [9] and combined with the Molecular Signature Database (MsigDB) v7.0 database (http://www.gsea-msigdb.org/gsea/msigdb/, GOBP_CELLULAR_COPPER_ION_HOMEOSTASIS, GOBP_CELLULAR_RESPONSE_TO_COPPER_ION). Cuproptosis-related gene sets obtained from Molecular Signature Database (MsigDB) v7.33 database.
XIAP autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
XIAP apoptosis 15098067 XIAP, a member of the inhibitor of apoptosis family of proteins (IAP), has been identified as a potent caspase inhibitor. retulator signature

Go Annotation:

GeneSymbol Go id
XIAP GO:0004842,GO:0004842,GO:0004869,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005829,GO:0006974,GO:0010804,GO:0016055,GO:0030510,GO:0031398,GO:0031398,GO:0032481,GO:0042127,GO:0042742,GO:0042802,GO:0042981,GO:0043027,GO:0043027,GO:0043066,GO:0043066,GO:0043066,GO:0043123,GO:0043154,GO:0045088,GO:0046330,GO:0046872,GO:0050727,GO:0051402,GO:0051726,GO:0055070,GO:0060785,GO:0061135,GO:0061630,GO:0061630,GO:0061630,GO:0061630,GO:0070424,GO:0070427,GO:0070431,GO:0070534,GO:0090263,GO:0090263,GO:0097340,GO:0120283,GO:1902530

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
XIAP hsa:331 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
XIAP hsa:331 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)
XIAP hsa:331 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)
XIAP hsa:331 path:hsa04210 Apoptosis - Homo sapiens (human)
XIAP hsa:331 path:hsa04215 Apoptosis - multiple species - Homo sapiens (human)
XIAP hsa:331 path:hsa04217 Necroptosis - Homo sapiens (human)
XIAP hsa:331 path:hsa04510 Focal adhesion - Homo sapiens (human)
XIAP hsa:331 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
XIAP hsa:331 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
XIAP hsa:331 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
XIAP hsa:331 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
XIAP hsa:331 path:hsa05200 Pathways in cancer - Homo sapiens (human)
XIAP hsa:331 path:hsa05207 Chemical carcinogenesis - receptor activation - Homo sapiens (human)
XIAP hsa:331 path:hsa05222 Small cell lung cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
XIAP DIABLO 10929711 11140637 11157976 15078891 17435549 22733138 23070005 23180781 26192618 26587781 association,physical association anti tag coimmunoprecipitation ACSN,InnateDB
NFKB1 XIAP 17435549 21725609 23178297 23180781 23572150 26192618 9653098 interaction type,physical association unspecified method ACSN,InnateDB
CAPN1 XIAP 19931333 26192618 28747251 interaction type N/A ACSN
HTRA2 XIAP 10521396 11583623 11801603 11803371 12815069 12835328 12865429 15200957 15201285 15781261 17311912 19935698 20125124 23070005 23180781 26192618 interaction type,biochemical,physical association affinity chromatography technology,anti tag coimmunoprecipitation,fluorescence polarization spectroscopy,gst pull down,mutation analysis,protease assay ACSN,InnateDB
XIAP CAPN2 11583623 12815069 12835328 21887410 23242420 26192618 interaction type N/A ACSN
XIAP UNC5A 11546791 12376548 26192618 association N/A ACSN
NGF XIAP 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 26192618 9841888 interaction type N/A ACSN
NGFR XIAP 10764727 11546791 11756498 12376548 12387875 14673001 15099563 15548667 15721744 16252010 16630834 17488777 17764704 22465479 23314527 25071162 26192618 9841888 interaction type N/A ACSN
ATF4 XIAP 23850759 26192618 26587781 interaction type N/A ACSN
ACVR1B XIAP 11356828 23180781 physical association anti tag coimmunoprecipitation InnateDB
STRADB XIAP 12048196 23180781 physical association two hybrid,gst pull down InnateDB
APAF1 XIAP 11230124 12181739 23180781 physical association gst pull down InnateDB
XIAP XIAP 10548111 11242052 11447297 11583623 11927604 14576775 15078891 23180781 26467481 9545235 ubiquitination reaction,bind,physical association,down-regulates activity,down-regulates quantity by destabilization anti tag coimmunoprecipitation,surface plasmon resonance,ubiquitination reaction InnateDB,Signor
BIRC5 XIAP 15218035 17613533 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
XIAP MAP3K7 11865055 12048196 23180781 physical association anti tag coimmunoprecipitation InnateDB
UBE2D1 XIAP 15218035 23180781 physical association gst pull down InnateDB
BRCA1 XIAP 16322207 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
CASP3 XIAP 11157976 11230124 11257232 11359776 11447297 11927604 12181739 12529384 12874265 15014070 15200957 17069460 19559631 23180781 9230442 9525868 9545235 ubiquitination reaction,protein cleavage,physical association affinity chromatography technology,anti tag coimmunoprecipitation,gst pull down,x-ray crystallography,ubiquitination reaction,protease assay InnateDB
CASP6 XIAP 15200957 23180781 9545235 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
XIAP CASP7 11257230 11257231 11359776 15200957 19559631 23180781 9230442 9525868 9545235 protein cleavage,physical association affinity chromatography technology,anti tag coimmunoprecipitation,gst pull down,x-ray crystallography,protease assay InnateDB
XIAP CASP9 11157976 11230124 11927604 12181739 15200957 15300255 23180781 25416956 9545235 ubiquitination reaction,physical association anti tag coimmunoprecipitation,two hybrid,gst pull down,ubiquitination reaction InnateDB
UBE2D3 XIAP 15749826 23180781 ubiquitination reaction ubiquitination reaction InnateDB
CHEK1 XIAP 14759516 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
CASP9 XIAP 12181739 16352606 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
XIAP CASP3 12181739 23180781 physical association gst pull down InnateDB
COMMD1 XIAP 14685266 23180781 ubiquitination reaction,physical association anti tag coimmunoprecipitation,two hybrid,ubiquitination reaction InnateDB
DIABLO XIAP 11157976 11242052 11257231 11606597 11927604 12121969 12181739 12660240 12865429 15078891 15300255 15749826 17686459 23180781 ubiquitination reaction,physical association affinity chromatography technology,anti tag coimmunoprecipitation,far western blotting,gst pull down,surface plasmon resonance,ubiquitination reaction InnateDB
GSPT1 XIAP 12865429 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,gst pull down InnateDB
XIAP TAB2 12048196 23180781 physical association anti tag coimmunoprecipitation InnateDB
SEPTIN4 XIAP 15029247 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
RAF1 XIAP 16964381 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,gst pull down,protein kinase assay InnateDB
HNRNPA1 XIAP 17287399 23180781 physical association affinity chromatography technology,nucleic acid uv cross-linking assay InnateDB
HNRNPC XIAP 12482981 17287399 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,nucleic acid uv cross-linking assay InnateDB
SSB XIAP 10848591 12482981 17287399 23180781 physical association affinity chromatography technology,anti tag coimmunoprecipitation,nucleic acid uv cross-linking assay InnateDB
TAB1 XIAP 11865055 12048196 17560374 23180781 9878061 physical association anti tag coimmunoprecipitation,surface plasmon resonance,x-ray crystallography InnateDB
AKT2 XIAP 14645242 23180781 phosphorylation reaction protein kinase assay InnateDB
TRAF6 XIAP 12048196 23180781 physical association anti tag coimmunoprecipitation InnateDB
APP XIAP 14576775 23180781 physical association surface plasmon resonance InnateDB
AFP XIAP 16869888 23180781 physical association anti tag coimmunoprecipitation InnateDB
CAPNS1 XIAP 12121983 23180781 biochemical protease assay InnateDB
HTRA4 XIAP 15201285 23180781 physical association anti tag coimmunoprecipitation InnateDB
BIRC6 XIAP 15507451 23180781 physical association anti tag coimmunoprecipitation InnateDB
XAF1 XIAP 17613533 23180781 physical association anti tag coimmunoprecipitation InnateDB
BIRC3 XIAP 17069460 23180781 physical association anti tag coimmunoprecipitation InnateDB
BIRC2 XIAP 17069460 23180781 physical association anti tag coimmunoprecipitation InnateDB
RIPK2 XIAP 19667203 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOD2 XIAP 19667203 23180781 physical association anti tag coimmunoprecipitation InnateDB
NOD1 XIAP 19667203 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIVA1 XIAP 19584092 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
TGFBR1 XIAP 19531477 23180781 physical association anti tag coimmunoprecipitation InnateDB
E2F1 XIAP 21653699 23180781 physical association pull down InnateDB
TOLLIP XIAP 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
GLI2 XIAP 21483830 23180781 physical association anti tag coimmunoprecipitation InnateDB
XIAP INPP5D 22815893 23180781 physical association anti tag coimmunoprecipitation InnateDB
XIAP CASP10 23180781 25416956 physical association two hybrid InnateDB
XIAP ERCC3 23180781 25416956 physical association two hybrid InnateDB
XIAP RFC5 23180781 25416956 physical association two hybrid InnateDB
XIAP RIPK2 23180781 25416956 physical association two hybrid InnateDB
XIAP NEK6 23180781 25416956 physical association two hybrid InnateDB
XIAP VPS37C 23180781 25416956 physical association two hybrid InnateDB
XIAP LONRF1 23180781 25416956 physical association two hybrid InnateDB
XIAP SSX2IP 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 XIAP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 XIAP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 XIAP 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 XIAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA XIAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF XIAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 XIAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS XIAP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR XIAP 20589722 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 XIAP 14739605 15041463 15756023 16157589 16453001 18223231 18566231 18761050 18978816 trascriptional regulation,stimulation inferred by curator TFlink
RELA XIAP 14739605 15041463 15756023 16157589 16453001 18223231 18566231 18761050 18978816 trascriptional regulation,stimulation inferred by curator TFlink
SP1 XIAP 17121920 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 XIAP 17121920 trascriptional regulation,stimulation inferred by curator TFlink
SSB XIAP 10848591 trascriptional regulation,stimulation inferred by curator TFlink
TP53 XIAP N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000012A1DD XIAP 21993663 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000171525 XIAP 21993663 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 XIAP 22161761 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000055BBE5 XIAP 21993663 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00000EED18 XIAP 22012620 22161761 25416803 28097098 mrna cleavage,inhibition array technology,clip,miRNA interference luciferase reporter assay TarBase
URS000012A1DD XIAP 21993663 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 XIAP 21993663 25416803 25985365 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000055BBE5 XIAP 21993663 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 XIAP 19074876 25416803 25444916 26676658 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00000B59A2 XIAP 19074876 25416803 25444916 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS000016FF9C XIAP 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000039E1E1 XIAP 21572407 23622248 23824327 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00002075FA XIAP 21572407 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000000B1C9 XIAP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070CD2 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000042E8CC XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FB065 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001270D3 XIAP 23824327 25416803 27456358 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00002C7B2B XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004505E4 XIAP 20371350 21572407 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075ADAC XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A XIAP 23592263 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000033EBB8 XIAP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C XIAP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 XIAP 23824327 24145606 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000321A1A XIAP 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA XIAP 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 XIAP 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 XIAP 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 XIAP 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 XIAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 XIAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A XIAP 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D XIAP 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 XIAP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039A25B XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 XIAP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE XIAP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000302909 XIAP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000E1E9E XIAP 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005E6F45 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FF522 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000ED600 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 XIAP 22927820 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 XIAP 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 XIAP 23824327 25416803 26231038 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS0000568FF8 XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00000DD591 XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F XIAP 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 XIAP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 XIAP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004AC389 XIAP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016D2D4 XIAP 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 XIAP 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 XIAP 25416803 26439986 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS00000C0D3F XIAP 25416803 27517917 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 XIAP 22135298 phosphorylation N/A PhosphoSite
IKBKE XIAP 22135298 phosphorylation N/A PhosphoSite
AKT2 XIAP 22135298 phosphorylation N/A PhosphoSite
AKT1 XIAP 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
RIPK2 XIAP 25361965 interaction type N/A PTMCode2
XIAP RIPK2 25361965 interaction type N/A PTMCode2
CASP9 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP9 25361965 interaction type N/A PTMCode2
AIFM1 XIAP 25361965 interaction type N/A PTMCode2
XIAP AIFM1 25361965 interaction type N/A PTMCode2
CASP2 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP2 25361965 interaction type N/A PTMCode2
CASP6 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP6 25361965 interaction type N/A PTMCode2
MAP3K2 XIAP 25361965 interaction type N/A PTMCode2
XIAP MAP3K2 25361965 interaction type N/A PTMCode2
CASP7 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP7 25361965 interaction type N/A PTMCode2
CASP3 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP3 25361965 interaction type N/A PTMCode2
STRADB XIAP 25361965 interaction type N/A PTMCode2
XIAP STRADB 25361965 interaction type N/A PTMCode2
XIAP AKT1 25361965 interaction type N/A PTMCode2
HTRA2 XIAP 25361965 interaction type N/A PTMCode2
XIAP HTRA2 25361965 interaction type N/A PTMCode2
BIRC5 XIAP 25361965 interaction type N/A PTMCode2
XIAP BIRC5 25361965 interaction type N/A PTMCode2
TRAF6 XIAP 25361965 interaction type N/A PTMCode2
XIAP TRAF6 25361965 interaction type N/A PTMCode2
DIABLO XIAP 25361965 interaction type N/A PTMCode2
XIAP DIABLO 25361965 interaction type N/A PTMCode2
BIRC2 XIAP 25361965 interaction type N/A PTMCode2
XIAP BIRC2 25361965 interaction type N/A PTMCode2
XIAP CASP8 25361965 interaction type N/A PTMCode2
CASP8 XIAP 25361965 interaction type N/A PTMCode2
XIAP XAF1 25361965 interaction type N/A PTMCode2
XAF1 XIAP 25361965 interaction type N/A PTMCode2
XIAP MAGED1 25361965 interaction type N/A PTMCode2
MAGED1 XIAP 25361965 interaction type N/A PTMCode2
XIAP CASP4 25361965 interaction type N/A PTMCode2
CASP4 XIAP 25361965 interaction type N/A PTMCode2
XIAP XIAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
GMCL1 XIAP 25348397 N/A physical interaction ComPPI
GOLGA2 XIAP 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
VPS37C XIAP 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2I XIAP 25348397 N/A physical interaction ComPPI
GCC1 XIAP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DYNLL1 XIAP 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HNRNPC XIAP 25348397 N/A physical interaction ComPPI
CKS1B XIAP 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TCF25 XIAP 25348397 N/A physical interaction ComPPI
DYNLL2 XIAP 14525934 16189514 24234451 25348397 27173435 association,physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
BOLA1 XIAP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CRYAB XIAP 25348397 N/A physical interaction ComPPI
S100A4 XIAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 XIAP 12048196 14525934 22493164 24234451 25241761 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
XIAP ERCC3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP CASP9 11242052 11390657 11801603 11927604 12620238 14525934 16189514 18022362 24234451 25241761 25348397 25416956 27107012 29997244 9545235 association,physical association anti tag coimmunoprecipitation,bioluminescence resonance energy transfer,two hybrid,cosedimentation in solution,experimental interaction detection,fluorescence polarization spectroscopy,pull down,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,biochemical,in vitro,in vivo,proximity ligation assay,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,HPRD,IntAct
XIAP MAGED1 11546791 14525934 24234451 24947323 25348397 27898060 physical association two hybrid,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
XIAP CASP3 11257232 11447297 11927604 14525934 19273858 24234451 25241761 25348397 9230442 9525868 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,x-ray crystallography,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
XIAP CASP7 11257230 11257231 11359776 14525934 24234451 25348397 9230442 9525868 physical association experimental interaction detection,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
XIAP MAP3K7 12048196 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XIAP TAB2 12048196 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XIAP DIABLO 10929712 11242052 11257231 11604410 11801603 14525934 16282325 21185211 22465666 23251006 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,fluorescence polarization spectroscopy,pull down,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
XIAP HTRA2 11583623 11602612 11604410 11606597 11801603 11803371 14525934 24234451 24698088 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,fluorescence polarization spectroscopy,pull down,surface plasmon resonance,physical interaction,in vitro ComPPI,HPRD,IntAct
XIAP COMMD1 14525934 14685242 18795889 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
XIAP XAF1 11175744 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
XIAP STRADB 12048196 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
XIAP ACVRL1 11356828 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
XIAP NTAQ1 14525934 16189514 24234451 25348397 27107012 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid ComPPI,HPRD,IntAct
XIAP BIRC5 14525934 15218035 24083380 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
XIAP NOTCH1 14525934 17318174 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
XIAP CHEK1 14525934 14759516 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
XIAP AKT1 14525934 14645242 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
XIAP AKT2 25348397 N/A physical interaction,in vitro,in vivo ComPPI
XIAP GSPT1 25348397 N/A physical interaction ComPPI
XIAP TAB1 14525934 24234451 25348397 27107012 9878061 physical association experimental interaction detection,physical interaction,validated two hybrid,barcode fusion genetics two hybrid ComPPI,HPRD,IntAct
XIAP CASP4 25348397 N/A physical interaction ComPPI
XIAP SERTAD1 19176394 25348397 25691055 27898060 N/A physical interaction ComPPI,OmniPath
XIAP RAF1 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
XIAP STUB1 25348397 N/A physical interaction ComPPI
XIAP MAP3K2 18761086 24234451 24975362 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
XIAP AIFM1 25348397 N/A physical interaction ComPPI
XIAP USP11 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP UBE2D2 19549727 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
XIAP UBE2D3 19549727 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
XIAP UBE2D4 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XIAP UBE2N 19549727 24234451 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study ComPPI,IntAct
XIAP UBE2V1 19549727 24234451 25260751 25348397 ubiquitination reaction,physical association two hybrid,physical interaction,two hybrid array,enzymatic study,ubiquitinase assay ComPPI,IntAct
XIAP UBE2V2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XIAP UBE2J2 25348397 N/A physical interaction ComPPI
XIAP UBE2W 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XIAP BIRC2 25348397 N/A physical interaction ComPPI
XIAP UBE2L3 25348397 N/A physical interaction ComPPI
XIAP EXTL3 25348397 N/A physical interaction ComPPI
XIAP BMPR1B 25348397 N/A physical interaction ComPPI
XIAP BMPR2 25348397 N/A physical interaction ComPPI
XIAP TRAF2 25348397 N/A physical interaction ComPPI
XIAP HAX1 20171186 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP UBE2E1 19549727 24234451 25348397 ubiquitination reaction physical interaction,enzymatic study ComPPI,IntAct
XIAP CCS 25348397 N/A physical interaction ComPPI
XIAP SEPTIN4 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
XIAP SIAH1 21185211 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP RIPK1 21931591 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
XIAP RIPK2 19667203 21931591 24234451 25348397 25416956 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP RIPK3 21931591 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
XIAP RIPK4 21931591 24234451 25348397 ubiquitination reaction,physical association pull down,physical interaction,enzymatic study ComPPI,IntAct
XIAP ERC1 25348397 N/A physical interaction ComPPI
XIAP PTEN 25348397 N/A physical interaction ComPPI
XIAP USP19 25348397 N/A physical interaction ComPPI
XIAP TOLLIP 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP TRIM32 21628460 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP ARHGDIA 21402697 22532870 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP ELAVL1 19322201 21102524 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP NOD2 19667203 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
XIAP UBC 17318174 18931663 22194841 23259674 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
XIAP SIVA1 25348397 N/A physical interaction ComPPI
XIAP TBK1 16887178 22072751 24234451 25348397 27898060 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct,OmniPath
XIAP IKBKE 25348397 N/A physical interaction ComPPI
XIAP IRF3 25348397 N/A physical interaction ComPPI
XIAP LATS1 25348397 N/A physical interaction ComPPI
XIAP RAC1 22117219 24234451 25301945 25348397 26279033 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct,OmniPath
XIAP BIRC3 25348397 N/A physical interaction ComPPI
XIAP APAF1 25348397 N/A physical interaction ComPPI
XIAP AFP 25348397 N/A physical interaction ComPPI
XIAP BAX 25348397 N/A physical interaction ComPPI
XIAP MDM2 25348397 N/A physical interaction ComPPI
XIAP HSPA4 25348397 N/A physical interaction ComPPI
XIAP NOD1 19667203 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
XIAP E2F1 21653699 25216527 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP HNRNPA1 25348397 N/A physical interaction ComPPI
XIAP SSB 25348397 N/A physical interaction ComPPI
XIAP GSK3B 25348397 N/A physical interaction ComPPI
XIAP HTRA1 21387310 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP AHCY 25348397 N/A physical interaction ComPPI
XIAP SEC23IP 25348397 N/A physical interaction ComPPI
XIAP ATP6V1A 25348397 N/A physical interaction ComPPI
XIAP USP5 25348397 N/A physical interaction ComPPI
XIAP UCHL3 25348397 N/A physical interaction ComPPI
XIAP PFAS 25348397 N/A physical interaction ComPPI
XIAP NUDCD2 25348397 N/A physical interaction ComPPI
XIAP USO1 25348397 N/A physical interaction ComPPI
XIAP PGAM5 25348397 N/A physical interaction ComPPI
XIAP CCT2 25348397 N/A physical interaction ComPPI
XIAP BIRC7 25348397 N/A physical interaction ComPPI
XIAP INPP5D 25348397 N/A physical interaction ComPPI
XIAP SCARA3 22683311 25348397 27898060 N/A physical interaction ComPPI,OmniPath
XIAP BRCA1 25348397 N/A physical interaction ComPPI
XIAP TRIM8 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XIAP DTX3 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
XIAP FAIM 25348397 N/A physical interaction ComPPI
XIAP CASP6 25348397 N/A physical interaction ComPPI
XIAP CASP8 25348397 N/A physical interaction ComPPI
XIAP CASP12 25348397 N/A physical interaction ComPPI
XIAP IMUP 25348397 N/A physical interaction ComPPI
XIAP MAP3K3 25348397 N/A physical interaction ComPPI
XIAP CASP10 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP RFC5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP NEK6 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP LONRF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP SSX2IP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
XIAP UBE2L6 25348397 N/A physical interaction ComPPI
XIAP PRDX3 25348397 N/A physical interaction ComPPI
XIAP PHB2 25348397 N/A physical interaction ComPPI
XIAP PRSS22 25348397 N/A physical interaction ComPPI
XIAP BIRC8 25348397 N/A physical interaction ComPPI
XIAP CLEC11A 25348397 N/A physical interaction ComPPI
XIAP GMCL2 25348397 N/A physical interaction ComPPI
XIAP C19ORF54 25348397 N/A physical interaction ComPPI
XIAP CEP170 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
XIAP SORT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP SMS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP SRPRA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP UBE2A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP RAPGEF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP CKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP RNPS1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP SAMD1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XIAP ACVR1B 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
XIAP CDCA4 25348397 N/A physical interaction ComPPI
XIAP TLE3 25348397 N/A physical interaction ComPPI
XIAP TCF7L2 25348397 N/A physical interaction ComPPI
XIAP EGFR 25348397 N/A physical interaction ComPPI
XIAP KLHL2 25348397 N/A physical interaction ComPPI
XIAP LRRN2 25348397 N/A physical interaction ComPPI
XIAP ADAMTS4 25348397 N/A physical interaction ComPPI
XIAP DCAF12 25348397 N/A physical interaction ComPPI
XIAP FAF1 25348397 N/A physical interaction ComPPI
XIAP HNRNPL 25348397 N/A physical interaction ComPPI
XIAP BCL2 25348397 N/A physical interaction ComPPI
XIAP UBB 14525934 15218035 25348397 N/A anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD
XIAP RPS27A 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
XIAP UBA52 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
XIAP UBE2Q2 19549727 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
XIAP RAC3 22117219 24234451 25348397 N/A pull down ComPPI,IntAct
XIAP RAC2 22117219 24234451 25348397 N/A pull down ComPPI,IntAct
XIAP NEDD8 22584050 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XIAP PPIH 24234451 25348397 27107012 physical association two hybrid array,two hybrid prey pooling approach,validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
XIAP DNM2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
XIAP QARS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XIAP MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XIAP PPM1K 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D1 XIAP 17318174 19549727 24234451 25348397 ubiquitination reaction,physical association pull down,physical interaction,two hybrid array,enzymatic study,two hybrid prey pooling approach ComPPI,IntAct
UBE2E2 XIAP 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
BCL10 XIAP 25348397 N/A physical interaction ComPPI
XIAP XIAP 11175744 12048196 14525934 16189514 19273858 24234451 27107012 physical association anti tag coimmunoprecipitation,experimental interaction detection,two hybrid pooling approach,validated two hybrid,barcode fusion genetics two hybrid,two hybrid HPRD,IntAct
XIAP TGFBR1 11356828 14525934 N/A experimental interaction detection HPRD
CAPNS1 XIAP 12121983 27898060 N/A N/A OmniPath
APP XIAP 14576775 27898060 N/A N/A OmniPath
MAP3K7 XIAP 11865055 12048196 19584092 27898060 N/A N/A OmniPath
XIAP MAP3K7 11865055 12048196 19584092 27898060 N/A N/A OmniPath
XIAP NOD2 19667203 22607974 27898060 N/A N/A OmniPath
RIPK2 XIAP 19667203 21931591 22607974 22815893 23818254 25416956 27898060 N/A N/A OmniPath
XIAP RIPK2 19667203 21931591 22607974 22815893 23818254 25416956 27898060 stimulant N/A OmniPath
IKBKE XIAP 22072751 27898060 N/A N/A OmniPath
XIAP CASP7 10508158 11257230 11257231 11257232 11359776 11447297 11583623 14512414 15200957 15580265 18521960 19559631 19698783 23074197 23979166 27898060 9230442 9384571 9525868 9545235 inhibition N/A OmniPath
CASP3 XIAP 10548111 11157976 11230124 11257230 11257232 11359776 11447297 11927604 12181739 12529384 12624662 12874265 15014070 15200957 15507451 15650747 15725726 16543147 16869888 17069460 17291493 18521960 18723680 19559631 19698783 22072751 22815893 23074197 23979166 25241761 26186194 27898060 9230442 9384571 9525868 9545235 inhibition N/A OmniPath
XIAP CASP3 10508158 10548111 11157976 11230124 11257230 11257232 11359776 11447297 11583623 11927604 12181739 12529384 12624662 12874265 15014070 15200957 15507451 15650747 15725726 16543147 16869888 17069460 17291493 18521960 18723680 19559631 19698783 22072751 22815893 23074197 23979166 25241761 26186194 27898060 9230442 9384571 9525868 9545235 inhibition N/A OmniPath
XIAP CASP9 10508158 11157976 11230124 11242052 11390657 11801603 11927604 12042762 12181739 12620238 14512414 14523016 15069192 15200957 15280366 15300255 15507451 15749826 16189514 16322207 16352606 16701639 17179183 17291493 18022362 19153467 19698783 23074197 25241761 25416956 27898060 9545235 inhibition N/A OmniPath
XIAP TRAF6 12048196 22493164 25241761 27898060 N/A N/A OmniPath
AKT1 XIAP 14645242 17698078 23640046 25241761 27898060 stimulant N/A OmniPath
RAF1 XIAP 16964381 19011619 25241761 27898060 stimulant N/A OmniPath
XIAP RAF1 16964381 19011619 25241761 27898060 N/A N/A OmniPath
EIF4G2 XIAP 11943866 27898060 stimulant N/A OmniPath
XIAP TAB2 12048196 27898060 stimulant N/A OmniPath
TAB2 XIAP 12048196 27898060 N/A N/A OmniPath
XIAP BIRC2 16263936 17069460 22711539 27898060 N/A N/A OmniPath
BIRC3 XIAP 17069460 24552816 27898060 N/A N/A OmniPath
BIRC5 XIAP 15218035 17613533 21536684 24083380 27898060 stimulant N/A OmniPath
XAF1 XIAP 11175744 12766484 17613533 22811387 27898060 inhibition N/A OmniPath
AKT2 XIAP 14645242 17537996 23749209 26314849 27898060 stimulant N/A OmniPath
XIAP AKT2 14645242 27898060 N/A N/A OmniPath
CAMKK1 XIAP 14645242 27898060 N/A N/A OmniPath
XIAP TAB1 11865055 12048196 17560374 27898060 9878061 stimulant N/A OmniPath
TAB1 XIAP 11865055 12048196 17560374 27898060 9878061 N/A N/A OmniPath
HTRA2 XIAP 11583623 11602612 11604410 11606597 11801603 11803371 12835328 12865429 15200957 15201285 15300255 15781261 17311912 17906618 24698088 27898060 inhibition N/A OmniPath
TGFBR1 XIAP 11356828 19531477 27898060 N/A N/A OmniPath
XIAP DIABLO 10929712 10972280 11140637 11140638 11157976 11242052 11257230 11257231 11602612 11604410 11606597 11801595 11801603 11927604 12121969 12181739 12218061 12511567 12525502 12660240 12865429 14512414 14523016 15078891 15178455 15200957 15280366 15300255 15507451 15541727 15650747 15749826 15781261 16282325 17179183 17686459 17724022 19153467 19506082 19667203 20957035 21185211 22465666 23251006 23818254 25246529 25801170 27898060 inhibition N/A OmniPath
DIABLO XIAP 10929711 10929712 10972280 11140637 11140638 11157976 11242052 11257230 11257231 11583623 11602612 11604410 11606597 11801595 11801603 11927604 12121969 12181739 12218061 12511567 12525502 12660240 12865429 14512414 14523016 15078891 15178455 15200957 15280366 15300255 15507451 15541727 15650747 15749826 15781261 16282325 17179183 17686459 17724022 19153467 19506082 19667203 20957035 21185211 22465666 23251006 23818254 25246529 25801170 27898060 inhibition,stimulant N/A OmniPath
XIAP NOD1 19667203 27898060 N/A N/A OmniPath
TOLLIP XIAP 21903422 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B45BE XIAP 27087310 direct interaction,inhibition N/A NPInter

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