Gene Information gene info

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GENE：PTRH2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTRH2
FullNmae peptidyl-tRNA hydrolase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24265
EnsembleID ENSG00000141378
Uniprot Q9Y3E5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTRH2 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTRH2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTRH2 anoikis 37679418 In our study, nine anoikis related genes (PTRH2, ITGAV, ANXA5, BIRC5, BDNF, BSG, DAP3, SKP2, and EGF) were determined to establish a risk scoring model using LASSO regression, which could be validated in ICGC dataset. retulator signature

Go Annotation:

GeneSymbol Go id
PTRH2 GO:0004045,GO:0004045,GO:0005515,GO:0005739,GO:0005739,GO:0005739,GO:0005741,GO:0005829,GO:0005829,GO:0006915,GO:0010629,GO:0016020,GO:2000210,GO:2000210,GO:2000811,GO:2000811

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 PTRH2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC PTRH2 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 PTRH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PTRH2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00000AA464 PTRH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE PTRH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000355E82 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C PTRH2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKD1 PTRH2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ATP6V1D PTRH2 25348397 N/A physical interaction ComPPI
CHCHD2 PTRH2 25348397 N/A physical interaction ComPPI
YIPF3 PTRH2 25348397 N/A physical interaction ComPPI
RPS15 PTRH2 25348397 N/A physical interaction ComPPI
MED21 PTRH2 25348397 N/A physical interaction ComPPI
JUP PTRH2 25348397 N/A physical interaction ComPPI
CD7 PTRH2 25348397 N/A physical interaction ComPPI
PTPN1 PTRH2 25348397 N/A physical interaction ComPPI
LAMTOR3 PTRH2 25348397 N/A physical interaction ComPPI
ABCC2 PTRH2 25348397 N/A physical interaction ComPPI
CLTC PTRH2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TLE5 PTRH2 15006356 22952044 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
SIGLEC10 PTRH2 25348397 N/A physical interaction ComPPI
GRPR PTRH2 25348397 N/A physical interaction ComPPI
HTR2C PTRH2 25348397 N/A physical interaction ComPPI
PTRH2 ATP6V0A1 25348397 N/A physical interaction ComPPI
PTRH2 ATP6V0A2 25348397 N/A physical interaction ComPPI
PTRH2 STT3B 25348397 N/A physical interaction ComPPI
PTRH2 FLOT1 25348397 N/A physical interaction ComPPI
PTRH2 RPS2 25348397 N/A physical interaction ComPPI
PTRH2 CD55 25348397 N/A physical interaction ComPPI
PTRH2 FLOT2 25348397 N/A physical interaction ComPPI
PTRH2 GADD45GIP1 25348397 N/A physical interaction ComPPI
PTRH2 PTK2 21383007 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
PTRH2 PHYHIP 25348397 N/A physical interaction ComPPI
PTRH2 ARHGEF10 25348397 N/A physical interaction ComPPI
PTRH2 DLK1 25348397 N/A physical interaction ComPPI
PTRH2 MINDY2 25348397 N/A physical interaction ComPPI
PTRH2 TNFRSF10B 25348397 N/A physical interaction ComPPI
PTRH2 CLEC5A 25348397 N/A physical interaction ComPPI
PTRH2 COQ9 25348397 N/A physical interaction ComPPI
PTRH2 DUSP22 25348397 N/A physical interaction ComPPI
PTRH2 DUSP6 25348397 N/A physical interaction ComPPI
PTRH2 DUSP8 25348397 N/A physical interaction ComPPI
PTRH2 DUSP9 25348397 N/A physical interaction ComPPI
PTRH2 EYA3 25348397 N/A physical interaction ComPPI
PTRH2 TLR5 25348397 N/A physical interaction ComPPI
PTRH2 CHRM3 25348397 N/A physical interaction ComPPI
PTRH2 SLC6A15 25348397 N/A physical interaction ComPPI
PTRH2 SLC18A1 25348397 N/A physical interaction ComPPI
PTRH2 HTR3A 25348397 N/A physical interaction ComPPI
PTRH2 SCGB2A2 25348397 N/A physical interaction ComPPI
PTRH2 TEX29 25348397 N/A physical interaction ComPPI
PTRH2 GPR21 25348397 N/A physical interaction ComPPI
PTRH2 HMOX2 25348397 N/A physical interaction ComPPI
PTRH2 SLC39A12 25348397 N/A physical interaction ComPPI
PTRH2 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PTRH2 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PTRH2 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PTRH2 CISD3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
PLGRKT PTRH2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSCB PTRH2 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
PRKD1 PTRH2 18703509 27898060 stimulant N/A OmniPath

Visualization










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