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GENE：AATF

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AATF
FullNmae apoptosis antagonizing transcription factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19235
EnsembleID ENSG00000275700
Uniprot Q9NY61

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AATF mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AATF immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AATF apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
AATF apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
AATF GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005667,GO:0005730,GO:0005730,GO:0005737,GO:0006357,GO:0006974,GO:0007155,GO:0007346,GO:0019901,GO:0032040,GO:0032929,GO:0040016,GO:0042274,GO:0042985,GO:0043066,GO:0043522,GO:0045944,GO:0048156,GO:2000378,GO:2001234

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MDM2 AATF 17468107 23180781 physical association anti tag coimmunoprecipitation InnateDB
AATF PIN1 17468107 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 AATF 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 AATF 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 AATF 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 AATF 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS000016C318 AATF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D AATF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 AATF 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002971AB AATF 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 AATF 23708386 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPKAPK2 AATF 22135298 phosphorylation N/A PhosphoSite
CHEK2 AATF 22135298 25361965 interaction type,phosphorylation N/A PhosphoSite,PTMCode2
ATM AATF 22135298 phosphorylation N/A PhosphoSite
AATF POLR2J 25361965 interaction type N/A PTMCode2
POLR2J AATF 25361965 interaction type N/A PTMCode2
AATF DAPK3 25361965 interaction type N/A PTMCode2
DAPK3 AATF 25361965 interaction type N/A PTMCode2
AATF PAWR 25361965 interaction type N/A PTMCode2
PAWR AATF 25361965 interaction type N/A PTMCode2
AATF MAPT 25361965 interaction type N/A PTMCode2
MAPT AATF 25361965 interaction type N/A PTMCode2
AATF MAGED1 25361965 interaction type N/A PTMCode2
MAGED1 AATF 25361965 interaction type N/A PTMCode2
AATF CHEK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 AATF 25348397 N/A physical interaction ComPPI
PCBD2 AATF 25348397 N/A physical interaction ComPPI
LDOC1 AATF 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TBL3 AATF 25348397 N/A physical interaction ComPPI
AATF RB1 10783144 12450794 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
AATF SP1 12847090 14525934 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
AATF TSG101 14525934 14761944 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
AATF DAPK3 10580117 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
AATF PAWR 14525934 14627703 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
AATF PALS2 14525934 15231747 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
AATF MPHOSPH6 14525934 15231747 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
AATF DAZAP2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AATF CHEK2 14525934 17157788 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
AATF ATM 14525934 17157788 24234451 25348397 phosphorylation reaction,physical association anti bait coimmunoprecipitation,experimental interaction detection,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
AATF ATR 14525934 17157788 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro,in vivo ComPPI,HPRD,IntAct
AATF RELA 14525934 17157788 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
AATF CHEK1 14525934 17157788 24234451 25348397 phosphorylation reaction experimental interaction detection,protein kinase assay,in vitro ComPPI,HPRD,IntAct
AATF MAPT 14697667 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
AATF RBL2 25348397 N/A physical interaction ComPPI
AATF RBL1 25348397 N/A physical interaction ComPPI
AATF SS18L1 25348397 N/A physical interaction ComPPI
AATF MAGED1 17488777 25348397 27898060 N/A physical interaction ComPPI,OmniPath
AATF SIRT7 25348397 N/A physical interaction ComPPI
AATF MDM2 25348397 N/A physical interaction ComPPI
AATF CAND1 25348397 N/A physical interaction ComPPI
AATF MMS19 25348397 N/A physical interaction ComPPI
AATF CPD 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AATF EFNB3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AATF SMAD3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AATF ZNF468 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
AATF LIN28A 25348397 N/A physical interaction ComPPI
AATF HIPK2 25348397 N/A physical interaction ComPPI
AATF AR 25348397 N/A physical interaction ComPPI
AATF NGDN 24234451 25348397 25416956 30021884 physical association cross-linking study,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
AATF NXF1 25348397 N/A physical interaction ComPPI
AATF OBSL1 25348397 N/A physical interaction ComPPI
AATF BTRC 25348397 N/A physical interaction ComPPI
AATF FBXW11 25348397 N/A physical interaction ComPPI
AATF RPS2 25348397 N/A physical interaction ComPPI
AATF RPS8 25348397 N/A physical interaction ComPPI
AATF DDX56 25348397 N/A physical interaction ComPPI
AATF ESF1 25348397 N/A physical interaction ComPPI
AATF KRR1 25348397 N/A physical interaction ComPPI
AATF NOL10 25348397 N/A physical interaction ComPPI
AATF WDR36 25348397 N/A physical interaction ComPPI
AATF BRIX1 25348397 N/A physical interaction ComPPI
AATF DDX52 25348397 N/A physical interaction ComPPI
AATF PUM3 25348397 N/A physical interaction ComPPI
AATF KRI1 25348397 N/A physical interaction ComPPI
AATF MPHOSPH10 25348397 N/A physical interaction ComPPI
AATF NOC2L 25348397 N/A physical interaction ComPPI
AATF NOL6 25348397 N/A physical interaction ComPPI
AATF RPF2 25348397 N/A physical interaction ComPPI
AATF IFI16 25348397 N/A physical interaction ComPPI
AATF CEP164 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AATF XPO1 25348397 N/A physical interaction ComPPI
AATF HNRNPU 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AATF RPL10 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AATF RTEL1 25348397 N/A physical interaction ComPPI
AATF AURKA 25348397 N/A physical interaction ComPPI
AATF CDC14B 25348397 N/A physical interaction ComPPI
AATF FGF8 25348397 N/A physical interaction ComPPI
AATF ZNF324B 25348397 N/A physical interaction ComPPI
AATF ZNF2 25348397 N/A physical interaction ComPPI
AATF FOXA1 25348397 N/A physical interaction ComPPI
AATF RBBP8 10783144 24234451 25348397 physical association two hybrid,pull down ComPPI,IntAct
AATF MAPKAPK2 22909821 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
AATF MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
AATF JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AATF TADA3 24234451 25348397 29232376 physical association anti tag coimmunoprecipitation,two hybrid ComPPI,IntAct
AATF TADA2A 24234451 25348397 29232376 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,confocal microscopy ComPPI,IntAct
AATF TADA2B 24234451 25348397 29232376 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,confocal microscopy ComPPI,IntAct
AATF KAT2A 24234451 25348397 29232376 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,confocal microscopy ComPPI,IntAct
AATF FBL 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AATF RPS6 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NEDD4L AATF 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
POLR2J AATF 10783144 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
LZTR1 AATF 25348397 N/A physical interaction ComPPI
EBNA1BP2 AATF 25348397 N/A physical interaction ComPPI
AATF LAMC3 24234451 30021884 physical association cross-linking study IntAct
MAPKAPK2 AATF 22909821 27898060 stimulant N/A OmniPath
CHEK2 AATF 17157788 27898060 N/A N/A OmniPath

Visualization










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