Gene Information gene info

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GENE：CDK11B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CDK11B
FullNmae cyclin dependent kinase 11B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1729
EnsembleID ENSG00000248333
Uniprot P21127

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CDK11B necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CDK11B mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CDK11B GO:0000278,GO:0001558,GO:0003723,GO:0004672,GO:0004674,GO:0004674,GO:0004693,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0005737,GO:0006355,GO:0006468,GO:0006468,GO:0006915,GO:0007346,GO:0050684,GO:0106310

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 CDK11B 18414489 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation array,chromatin immunoprecipitation assay TFlink
GATA3 CDK11B 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC CDK11B 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
NFE2L1 CDK11B 12115485 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CDK11B N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 CDK11B N/A 15685193 rna interference,inhibition array technology miRSponge

Source Target Pmid Interactiontype Methods Database
CDK7 CDK11B 22135298 phosphorylation N/A PhosphoSite
CDK11B EIF3F 22135298 phosphorylation N/A PhosphoSite
CHEK2 CDK11B 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KPNA2 CDK11B 25348397 N/A physical interaction ComPPI
PIN1 CDK11B 25348397 N/A physical interaction ComPPI
SAP30BP CDK11B 25348397 N/A physical interaction ComPPI
HSPA8 CDK11B 25348397 N/A physical interaction ComPPI
RARA CDK11B 24234451 25303530 25348397 association pull down ComPPI,IntAct
YWHAG CDK11B 25348397 N/A physical interaction,in vitro,in vivo ComPPI
MCM6 CDK11B 25348397 N/A physical interaction ComPPI
MCM2 CDK11B 25348397 N/A physical interaction ComPPI
HSP90AB1 CDK11B 25348397 N/A physical interaction ComPPI
PAK1 CDK11B 12624090 16413544 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
CASP3 CDK11B 25348397 N/A in vitro ComPPI
VDR CDK11B 25348397 N/A physical interaction ComPPI
SMAD3 CDK11B 25348397 N/A physical interaction ComPPI
PNKP CDK11B 25348397 N/A physical interaction ComPPI
TGM2 CDK11B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KPNB1 CDK11B 25348397 N/A physical interaction ComPPI
YWHAB CDK11B 25348397 N/A physical interaction,in vitro,in vivo ComPPI
YWHAZ CDK11B 25348397 N/A physical interaction ComPPI
CDKN2A CDK11B 25348397 N/A physical interaction ComPPI
RPS27A CDK11B 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSP90AA1 CDK11B 25348397 N/A physical interaction ComPPI
NTRK1 CDK11B 25348397 N/A physical interaction ComPPI
PRPF40A CDK11B 25348397 N/A physical interaction ComPPI
CASP1 CDK11B 25348397 N/A in vitro ComPPI
PELP1 CDK11B 25348397 N/A physical interaction ComPPI
CASP8 CDK11B 25348397 N/A in vitro ComPPI
CSNK2A1 CDK11B 25348397 N/A physical interaction ComPPI
UHRF2 CDK11B 25348397 N/A physical interaction ComPPI
ZNF510 CDK11B 25348397 N/A physical interaction ComPPI
PSMD1 CDK11B 25348397 N/A physical interaction ComPPI
RANBP9 CDK11B 14511641 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PDHA1 CDK11B 25348397 N/A physical interaction ComPPI
CTR9 CDK11B 25348397 N/A physical interaction ComPPI
EIF3F CDK11B 19245811 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
RAP1A CDK11B 25348397 N/A physical interaction ComPPI
YWHAQ CDK11B 25348397 N/A physical interaction,in vitro,in vivo ComPPI
SPRR3 CDK11B 25348397 N/A physical interaction ComPPI
CSNK2A2 CDK11B 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
SOX2 CDK11B 25348397 N/A physical interaction ComPPI
H1-4 CDK11B 25348397 N/A physical interaction ComPPI
YWHAE CDK11B 25348397 N/A physical interaction,in vitro,in vivo ComPPI
HSPA4 CDK11B 25348397 N/A physical interaction ComPPI
SUPT16H CDK11B 25348397 N/A physical interaction ComPPI
NOLC1 CDK11B 25348397 N/A physical interaction ComPPI
CDK7 CDK11B 24234451 25348397 29568061 association physical interaction,protein kinase assay,proximity-dependent biotin identification ComPPI,IntAct
SPAG9 CDK11B 25348397 N/A physical interaction ComPPI
TH CDK11B 25348397 N/A two hybrid,in vitro ComPPI
ZRSR2 CDK11B 25348397 N/A physical interaction ComPPI
SF1 CDK11B 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
MSN CDK11B 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KAT7 CDK11B 15963510 21988832 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid pooling approach,imaging technique,in vitro,in vivo ComPPI,IntAct
AP3D1 CDK11B 25348397 N/A physical interaction ComPPI
CDK8 CDK11B 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AP3B1 CDK11B 25348397 N/A physical interaction ComPPI
CDC37 CDK11B 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
AP2M1 CDK11B 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
DDB2 CDK11B 25348397 N/A physical interaction ComPPI
CCNL1 CDK11B 25348397 N/A physical interaction ComPPI
CCNL2 CDK11B 25348397 N/A physical interaction,in vivo ComPPI
EPS15L1 CDK11B 25348397 N/A physical interaction ComPPI
ESR1 CDK11B 25348397 N/A physical interaction ComPPI
MCM4 CDK11B 25348397 N/A physical interaction ComPPI
AP4M1 CDK11B 25348397 N/A physical interaction ComPPI
CDK11B CCND3 21988832 24234451 25348397 physical association two hybrid,physical interaction,in vitro,in vivo ComPPI,IntAct
CDK11B URM1 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDK11B RNPS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK11B SKIV2L 25348397 N/A physical interaction ComPPI
CDK11B B4GALT1 25348397 N/A physical interaction ComPPI
CDK11B MEPCE 25348397 N/A physical interaction ComPPI
CDK11B HSP90AA2P 25348397 N/A physical interaction ComPPI
CDK11B POU2F1 25348397 N/A physical interaction ComPPI
CDK11B RBM25 25348397 N/A physical interaction ComPPI
CDK11B GADD45A 25348397 N/A physical interaction ComPPI
CDK11B TPPP 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDK11B CSNK2B 25348397 N/A physical interaction ComPPI
CDK11B A2M 25348397 N/A physical interaction ComPPI
CDK11B ZNF875 25348397 N/A physical interaction ComPPI
CDK11B ZNF267 25348397 N/A physical interaction ComPPI
CDK11B ZNF460 25348397 N/A physical interaction ComPPI
CDK11B ZFP14 25348397 N/A physical interaction ComPPI
CDK11B ZNF33A 25348397 N/A physical interaction ComPPI
CDK11B CDKN2A 25348397 N/A physical interaction ComPPI
CDK11B NOP58 25348397 N/A physical interaction ComPPI
CDK11B CDK11A 25348397 N/A physical interaction ComPPI
CDK11B FKBP5 25348397 N/A physical interaction ComPPI
CDK11B WDR47 25348397 N/A physical interaction ComPPI
CDK11B ZG16B 25348397 N/A physical interaction ComPPI
CDK11B CUSTOS 25348397 N/A physical interaction ComPPI
CDK11B CRNN 25348397 N/A physical interaction ComPPI
CDK11B DPF2 25348397 N/A physical interaction ComPPI
CDK11B MED4 25348397 N/A physical interaction ComPPI
CDK11B FOXK2 25348397 N/A physical interaction ComPPI
CDK11B KMT2E 25348397 N/A physical interaction ComPPI
CDK11B JMJD6 25348397 N/A physical interaction ComPPI
CDK11B RSBN1 25348397 N/A physical interaction ComPPI
CDK11B ZNF221 25348397 N/A physical interaction ComPPI
CDK11B FGF8 25348397 N/A physical interaction ComPPI
CDK11B CCT6B 25348397 N/A physical interaction ComPPI
CDK11B CCT6A 25348397 N/A physical interaction ComPPI
CDK11B CCT2 25348397 N/A physical interaction ComPPI
CDK11B CCT3 25348397 N/A physical interaction ComPPI
CDK11B CCT4 25348397 N/A physical interaction ComPPI
CDK11B USP15 25348397 N/A physical interaction ComPPI
CDK11B IVNS1ABP 25348397 N/A physical interaction ComPPI
CDK11B NCL 25348397 N/A physical interaction ComPPI
CDK11B RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
C18ORF25 CDK11B 25348397 N/A physical interaction ComPPI
LEO1 CDK11B 25348397 N/A physical interaction ComPPI
DDX41 CDK11B 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
SRC CDK11B 15883043 27898060 N/A N/A OmniPath
CHEK2 CDK11B 23178491 27898060 N/A N/A OmniPath
CDK11B EIF3F 12446680 19245811 27898060 inhibition N/A OmniPath
CDK7 CDK11B 16327805 27898060 stimulant N/A OmniPath
CDK11A CDK11B 21078675 27898060 stimulant N/A OmniPath

Visualization










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