Gene Information gene info

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GENE：ANXA6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ANXA6
FullNmae annexin A6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:544
EnsembleID ENSG00000197043
Uniprot P08133

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ANXA6 mpt 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ANXA6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ANXA6 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ANXA6 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ANXA6 GO:0001755,GO:0001778,GO:0001786,GO:0003418,GO:0005262,GO:0005509,GO:0005515,GO:0005525,GO:0005525,GO:0005544,GO:0005544,GO:0005737,GO:0005739,GO:0005765,GO:0005925,GO:0005925,GO:0006937,GO:0008289,GO:0015276,GO:0015276,GO:0015485,GO:0015485,GO:0016020,GO:0031902,GO:0034220,GO:0035374,GO:0042383,GO:0042470,GO:0042802,GO:0048306,GO:0048471,GO:0051015,GO:0051283,GO:0051560,GO:0062023,GO:0070062,GO:0070588,GO:0097190

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ANXA6 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR ANXA6 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 ANXA6 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ANXA6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ANXA6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ANXA6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ANXA6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ANXA6 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ANXA6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D ANXA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D ANXA6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002C83DA ANXA6 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002D349B ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS0000116F83 ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00000A939F ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000007A060 ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS000075AB0E ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00005651EE ANXA6 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
S100B ANXA6 25361965 interaction type N/A PTMCode2
ANXA6 S100B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC73 ANXA6 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CUL5 ANXA6 25348397 N/A physical interaction ComPPI
TXN2 ANXA6 25348397 N/A physical interaction ComPPI
S100B ANXA6 14525934 25348397 9883272 N/A experimental interaction detection,physical interaction ComPPI,HPRD
S100A1 ANXA6 14525934 25348397 9883272 N/A experimental interaction detection,physical interaction ComPPI,HPRD
LMNA ANXA6 25348397 N/A physical interaction ComPPI
ACTB ANXA6 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
POLE3 ANXA6 25348397 N/A physical interaction ComPPI
ERBB2 ANXA6 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CD4 ANXA6 25348397 N/A physical interaction ComPPI
PRKCA ANXA6 25348397 N/A physical interaction ComPPI
CD9 ANXA6 23289620 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
GRB2 ANXA6 12577067 24234451 25348397 association pull down ComPPI,IntAct
TBCB ANXA6 25348397 N/A physical interaction ComPPI
U2AF2 ANXA6 25348397 N/A physical interaction ComPPI
NTRK1 ANXA6 25348397 N/A physical interaction ComPPI
HNRNPL ANXA6 25348397 N/A physical interaction ComPPI
EWSR1 ANXA6 25348397 N/A physical interaction ComPPI
RASA1 ANXA6 10571081 14525934 25348397 27898060 8798684 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
UBE2A ANXA6 25348397 N/A physical interaction ComPPI
SF1 ANXA6 24234451 25348397 26420826 association anti bait coimmunoprecipitation ComPPI,IntAct
MME ANXA6 23289620 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SMURF1 ANXA6 25348397 N/A physical interaction ComPPI
SNCA ANXA6 25348397 N/A physical interaction ComPPI
TRIM25 ANXA6 25348397 N/A physical interaction ComPPI
H2AX ANXA6 25348397 N/A physical interaction ComPPI
UBE2H ANXA6 25348397 N/A physical interaction ComPPI
THOP1 ANXA6 25348397 N/A physical interaction ComPPI
MLH1 ANXA6 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RHOU ANXA6 25348397 N/A physical interaction ComPPI
CR2 ANXA6 14525934 1831222 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
ADSS2 ANXA6 25348397 N/A physical interaction ComPPI
HPRT1 ANXA6 25348397 N/A physical interaction ComPPI
MSH2 ANXA6 25348397 N/A physical interaction ComPPI
IDH1 ANXA6 25348397 N/A physical interaction ComPPI
PLS3 ANXA6 25348397 N/A physical interaction ComPPI
GOT1 ANXA6 25348397 N/A physical interaction ComPPI
SIRT7 ANXA6 25348397 N/A physical interaction ComPPI
METTL18 ANXA6 25348397 N/A physical interaction ComPPI
MTNR1B ANXA6 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
ATP6V0A2 ANXA6 25348397 N/A physical interaction ComPPI
MTAP ANXA6 25348397 N/A physical interaction ComPPI
TJP1 ANXA6 16944923 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
G3BP1 ANXA6 25348397 N/A physical interaction ComPPI
NAMPT ANXA6 25348397 N/A physical interaction ComPPI
ANXA6 ATP4A 25348397 N/A physical interaction ComPPI
ANXA6 CCDC8 25348397 N/A physical interaction ComPPI
ANXA6 PPME1 25348397 N/A physical interaction ComPPI
ANXA6 TPD52 14525934 15576473 27898060 N/A experimental interaction detection HPRD,OmniPath
ANXA6 A2M 14525934 15226301 27898060 N/A experimental interaction detection HPRD,OmniPath
METTL14 ANXA6 24234451 29507755 association anti tag coimmunoprecipitation IntAct
ANXA6 LRRC45 24234451 30021884 physical association cross-linking study IntAct
RPL7A ANXA6 24234451 30021884 physical association cross-linking study IntAct
ANXA6 CPNE6 24234451 30021884 physical association cross-linking study IntAct
ANXA6 CHST11 24234451 30021884 physical association cross-linking study IntAct

Visualization










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