GENE：ASAH2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ASAH2 |
| FullNmae | N-acylsphingosine amidohydrolase 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18860 |
| EnsembleID | ENSG00000188611 |
| Uniprot | Q9NR71 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ASAH2 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ASAH2 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ASAH2 | GO:0000139,GO:0005509,GO:0005576,GO:0005739,GO:0005794,GO:0005886,GO:0005886,GO:0005901,GO:0006670,GO:0006670,GO:0006672,GO:0006915,GO:0007346,GO:0008270,GO:0017040,GO:0017040,GO:0017040,GO:0042759,GO:0044241,GO:0045121,GO:0046512,GO:0046512,GO:0046513,GO:0046513,GO:0046514,GO:0046514,GO:0046514,GO:0070062,GO:0071345,GO:0102121,GO:2001234 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ASAH2 | hsa:56624 | path:hsa00600 | Sphingolipid metabolism - Homo sapiens (human) |
| ASAH2 | hsa:56624 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| ASAH2 | hsa:56624 | path:hsa04071 | Sphingolipid signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000038446A | ASAH2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005ACA7C | ASAH2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B7450 | ASAH2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000412AC7 | ASAH2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000759EB8 | ASAH2 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | ASAH2 | 23313552 23824327 24906430 25416803 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | ASAH2 | 23313552 23824327 24906430 25416803 26701625 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | ASAH2 | 19536157 23313552 23824327 24906430 25416803 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | ASAH2 | 19536157 23313552 23824327 24906430 25416803 27418678 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | ASAH2 | 23824327 24906430 25416803 26701625 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000047944F | ASAH2 | 23824327 24906430 25416803 26701625 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFEC1 | ASAH2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000475586 | ASAH2 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |