GENE:AVP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AVP |
| FullNmae | arginine vasopressin |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:894 |
| EnsembleID | ENSG00000101200 |
| Uniprot | P01185 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AVP | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| AVP | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AVP | GO:0002125,GO:0003084,GO:0004672,GO:0005102,GO:0005184,GO:0005184,GO:0005185,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0005829,GO:0006091,GO:0006833,GO:0007165,GO:0007204,GO:0007267,GO:0007621,GO:0007625,GO:0007626,GO:0008284,GO:0010628,GO:0014049,GO:0030141,GO:0030307,GO:0030425,GO:0030669,GO:0031394,GO:0031894,GO:0031894,GO:0031895,GO:0032849,GO:0033138,GO:0033574,GO:0035094,GO:0035176,GO:0042310,GO:0042711,GO:0043027,GO:0043066,GO:0043154,GO:0045471,GO:0045907,GO:0046718,GO:0050891,GO:0051970,GO:0070371,GO:0070528,GO:0090201,GO:0098992 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AVP | hsa:551 | path:hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
| AVP | hsa:551 | path:hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| AVP | hsa:551 | path:hsa04270 | Vascular smooth muscle contraction - Homo sapiens (human) |
| AVP | hsa:551 | path:hsa04962 | Vasopressin-regulated water reabsorption - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MYC | AVP | 12695333 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AVP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AVP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AVP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AVP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | AVP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR1 | AVP | 11089536 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ESR2 | AVP | 11089536 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| REST | AVP | 12220737 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| AR | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ATF1 | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU3F1 | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| POU3F2 | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| USF1 | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| USF2 | AVP | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CRYAB | AVP | 16274233 17075130 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| CDKN2C | AVP | 25348397 | N/A | physical interaction | ComPPI |
| GEMIN6 | AVP | 25348397 | N/A | physical interaction | ComPPI |
| TXNDC17 | AVP | 14525934 14607844 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| AVP | OXTR | 14525934 25348397 27898060 7921229 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| AVP | AVPR2 | 11857925 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| AVP | AVPR1B | 14525934 25348397 7929452 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| AVP | AVPR1A | 14525934 25348397 8106369 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| AVP | KMT2A | 25348397 | N/A | physical interaction | ComPPI |
| AVP | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | DLX2 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | VHL | 25348397 | N/A | physical interaction | ComPPI |
| AVP | NIF3L1 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | HTRA1 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | FNTB | 25348397 | N/A | physical interaction | ComPPI |
| AVP | ATE1 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | ARSB | 25348397 | N/A | physical interaction | ComPPI |
| AVP | BDH2 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | GALNT18 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | B4GALT6 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | B4GALT5 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | CUL2 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | NDUFAF5 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | CHST3 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | MICA | 25348397 | N/A | physical interaction | ComPPI |
| AVP | ST3GAL4 | 25348397 | N/A | physical interaction | ComPPI |
| AVP | NAGLU | 25348397 | N/A | physical interaction | ComPPI |
| AVP | PRKAB2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AVP | AVPR2 | 11857925 1560825 27898060 | stimulant | N/A | OmniPath |
| AVP | AVPR1A | 1560825 27898060 8106369 | stimulant | N/A | OmniPath |
