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GENE：BCL2L12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BCL2L12
FullNmae BCL2 like 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13787
EnsembleID ENSG00000126453
Uniprot Q9HB09

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BCL2L12 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BCL2L12 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BCL2L12 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BCL2L12 GO:0005634,GO:0006915,GO:0016020,GO:0045944,GO:1990001,GO:2001236

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 BCL2L12 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 BCL2L12 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC BCL2L12 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 BCL2L12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BCL2L12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BCL2L12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 BCL2L12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BCL2L12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE BCL2L12 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 BCL2L12 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS000035CC3E BCL2L12 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 BCL2L12 25416803 26297542 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000D2680 BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D860 BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075D15B BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00005485E8 BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 BCL2L12 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000042619A BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000171CD1 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041CB9C BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000040EE1D BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F0F49 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000475586 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000007D64A BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000F6E49 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000039607D BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001941B8 BCL2L12 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GSK3B BCL2L12 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SGTA BCL2L12 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BCL2L1 BCL2L12 11283018 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PPP1R9A BCL2L12 25348397 N/A physical interaction ComPPI
UBC BCL2L12 25348397 N/A pull down ComPPI
HSPA1A BCL2L12 25348397 N/A anti tag coimmunoprecipitation ComPPI
HSPA1B BCL2L12 25348397 N/A anti tag coimmunoprecipitation ComPPI
HSPA4 BCL2L12 19376117 25348397 27898060 N/A physical interaction ComPPI,OmniPath
BAX BCL2L12 25348397 N/A physical interaction ComPPI
BCL2L12 AMY2A 25348397 N/A physical interaction ComPPI
BCL2L12 TP53 25348397 N/A physical interaction ComPPI
GSK3B BCL2L12 22262180 27898060 stimulant N/A OmniPath

Visualization










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