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GENE：BCL2L14

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol BCL2L14
FullNmae BCL2 like 14
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16657
EnsembleID ENSG00000121380
Uniprot Q9BZR8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
BCL2L14 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
BCL2L14 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
BCL2L14 GO:0005515,GO:0005829,GO:0005829,GO:0006915,GO:0012505,GO:0016020,GO:0019901,GO:0043229,GO:2001236

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BCL2L14 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR BCL2L14 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 BCL2L14 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 BCL2L14 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 BCL2L14 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 BCL2L14 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 BCL2L14 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000075B0F8 BCL2L14 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 BCL2L14 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000032BDF4 BCL2L14 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MELK BCL2L14 25361965 interaction type N/A PTMCode2
BCL2L14 MELK 25361965 interaction type N/A PTMCode2
BCL2L14 BCL2 25361965 interaction type N/A PTMCode2
BCL2 BCL2L14 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TRAPPC2B BCL2L14 25348397 N/A physical interaction ComPPI
BCL2L1 BCL2L14 11054413 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
DDIT4L BCL2L14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PICK1 BCL2L14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COPS5 BCL2L14 18006276 25348397 27898060 N/A physical interaction ComPPI,OmniPath
CHEK1 BCL2L14 25348397 N/A physical interaction ComPPI
VHL BCL2L14 25348397 N/A physical interaction ComPPI
MELK BCL2L14 17280616 24234451 25348397 27898060 phosphorylation reaction,physical association anti tag coimmunoprecipitation,pull down,protein kinase assay ComPPI,IntAct,OmniPath
BCL2 BCL2L14 11054413 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRAPPC2 BCL2L14 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC10 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC4 25348397 N/A physical interaction ComPPI
BCL2L14 MTA2 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC14 25348397 N/A physical interaction ComPPI
BCL2L14 PPP2R2D 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC9 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC6B 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC1 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC3 25348397 N/A physical interaction ComPPI
BCL2L14 TRAPPC2L 25348397 N/A physical interaction ComPPI
TRAPPC5 BCL2L14 25348397 N/A physical interaction ComPPI
TP53 BCL2L14 18431400 27898060 stimulant N/A OmniPath

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