GENE：CD44
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CD44 |
| FullNmae | CD44 molecule (IN blood group) |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1681 |
| EnsembleID | ENSG00000026508 |
| Uniprot | P16070 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CD44 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CD44 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CD44 | ferroptosis | 39321891 | Dynamic simulation and cellular thermal shift assay identified platycodin D as a natural plant extract for inhibiting ferroptosis by targeting CD44 in GCs. | retulator signature |
| CD44 | ferroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| CD44 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CD44 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CD44 | GO:0004888,GO:0004896,GO:0004896,GO:0005515,GO:0005518,GO:0005540,GO:0005540,GO:0005540,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0005902,GO:0005925,GO:0006954,GO:0007155,GO:0007155,GO:0007160,GO:0009986,GO:0016323,GO:0016324,GO:0016477,GO:0019221,GO:0030214,GO:0030667,GO:0031258,GO:0033138,GO:0034116,GO:0035692,GO:0035692,GO:0042110,GO:0042995,GO:0043066,GO:0043154,GO:0043518,GO:0044319,GO:0044344,GO:0050731,GO:0051216,GO:0070062,GO:0070374,GO:0070374,GO:0070487,GO:0098609,GO:1900625,GO:1902166,GO:2000392 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CD44 | hsa:960 | path:hsa04512 | ECM-receptor interaction - Homo sapiens (human) |
| CD44 | hsa:960 | path:hsa04640 | Hematopoietic cell lineage - Homo sapiens (human) |
| CD44 | hsa:960 | path:hsa05131 | Shigellosis - Homo sapiens (human) |
| CD44 | hsa:960 | path:hsa05169 | Epstein-Barr virus infection - Homo sapiens (human) |
| CD44 | hsa:960 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
| CD44 | hsa:960 | path:hsa05206 | MicroRNAs in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CD44 | ICAM1 | 22566907 23620508 23886063 26192618 | interaction type | N/A | ACSN |
| CD44 | TLN1 | 22566907 23620508 23886063 26192618 | interaction type | N/A | ACSN |
| CD44 | TLR2 | 18322236 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| LGALS9 | CD44 | 20206131 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CD44 | BMPR2 | 20206131 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CD44 | CEBPB | 20357818 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| CD44 | EGR1 | 20357818 23180781 | physical association | electrophoretic mobility supershift assay | InnateDB |
| CD44 | RELA | 12208876 20357818 23180781 | physical association | anti tag coimmunoprecipitation,electrophoretic mobility supershift assay | InnateDB |
| VCAN | CD44 | 10950950 23180781 | physical association | solid phase assay | InnateDB |
| CD44 | ROCK1 | 15090545 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CD44 | SLC9A3R1 | 15090545 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CD44 | HYAL2 | 15090545 23180781 | physical association | anti tag coimmunoprecipitation | InnateDB |
| CD44 | CD44 | 21659548 29145629 7509040 | physical association | inferred by curator | Reactome |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CD44 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CD44 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CD44 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CD44 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CD44 | 14604992 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CD44 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTNNB1 | CD44 | 17724465 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HDAC1 | CD44 | 18372343 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HMGA1 | CD44 | 15901130 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| IKBKB | CD44 | 18600306 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MYCN | CD44 | 19885598 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMARCA1 | CD44 | 14604992 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SMARCB1 | CD44 | 14604992 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SNAI2 | CD44 | 20509143 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | CD44 | 12972613 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | CD44 | 12972613 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TCF7L2 | CD44 | 16311123 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TCF4 | CD44 | 16311123 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TWIST1 | CD44 | 17487558 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TWIST2 | CD44 | 17487558 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| JUN | CD44 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000013ABA3 | CD44 | 21149267 | rna interference,inhibition | western blot,immunohistochemistry,miRNA interference luciferase reporter assay | miRSponge |
| URS00005FDE70 | CD44 | 18560585 \N | rna interference,inhibition | experimental interaction detection,miRNA interference luciferase reporter assay | miRSponge |
| URS000007A060 | CD44 | 21149267 | rna interference,inhibition | western blot,immunohistochemistry,miRNA interference luciferase reporter assay | miRSponge |
| URS00000EED18 | CD44 | 21240262 | rna interference,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry | miRSponge |
| URS0000508C13 | CD44 | 18193036 19158933 \N | rna interference,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS000019D79B | CD44 | 22552290 | rna interference,inhibition | quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
| URS00005FDE70 | CD44 | 18560585 18927107 24318997 25416803 25479940 27923017 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
| URS0000508C13 | CD44 | 18193036 18927107 19158933 25416803 27512943 | mrna cleavage,inhibition | experimental interaction detection,western blot,chromatin immunoprecipitation assay,rna immunoprecipitation,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miR2Disease,TarBase |
| URS00000EED18 | CD44 | 21240262 24423412 25416803 25551284 25572695 26231042 27497057 | mrna cleavage,inhibition | experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS000007A060 | CD44 | 21149267 25416803 | mrna cleavage,inhibition | western blot,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS000013ABA3 | CD44 | 21149267 25416803 | mrna cleavage,inhibition | western blot,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS000019D79B | CD44 | 22552290 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS0000065D58 | CD44 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00000EC1BE | CD44 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00003CF1AD | CD44 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000041CB9C | CD44 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000008A99 | CD44 | 23128394 25416803 26722463 27121210 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00004F4657 | CD44 | 23128394 25416803 28428713 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00000B59A2 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075E2C3 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170D8B | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000214763 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005194EC | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003AA845 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042B108 | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001B0D1E | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | CD44 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000044FD7 | CD44 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | CD44 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | CD44 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | CD44 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000083D87 | CD44 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F4AC3 | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002394F5 | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F24A9 | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EE123 | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002578DA | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000235862 | CD44 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CAMK2A | CD44 | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKACA | CD44 | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKCA | CD44 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGF2 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | FGF2 | 25361965 | interaction type | N/A | PTMCode2 |
| MMP7 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | MMP7 | 25361965 | interaction type | N/A | PTMCode2 |
| CD4 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | CD4 | 25361965 | interaction type | N/A | PTMCode2 |
| TP53 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | TP53 | 25361965 | interaction type | N/A | PTMCode2 |
| EGFR | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | EGFR | 25361965 | interaction type | N/A | PTMCode2 |
| CD74 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | CD74 | 25361965 | interaction type | N/A | PTMCode2 |
| SRGN | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | SRGN | 25361965 | interaction type | N/A | PTMCode2 |
| ERBB2 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | ERBB2 | 25361965 | interaction type | N/A | PTMCode2 |
| COL1A1 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | COL1A1 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | TIAM1 | 25361965 | interaction type | N/A | PTMCode2 |
| TIAM1 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | EPB41 | 25361965 | interaction type | N/A | PTMCode2 |
| EPB41 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | COL1A2 | 25361965 | interaction type | N/A | PTMCode2 |
| COL1A2 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | MMP1 | 25361965 | interaction type | N/A | PTMCode2 |
| MMP1 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | SELE | 25361965 | interaction type | N/A | PTMCode2 |
| SELE | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | ARHGEF1 | 25361965 | interaction type | N/A | PTMCode2 |
| ARHGEF1 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | LCK | 25361965 | interaction type | N/A | PTMCode2 |
| LCK | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | EZR | 25361965 | interaction type | N/A | PTMCode2 |
| EZR | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | ERBB4 | 25361965 | interaction type | N/A | PTMCode2 |
| ERBB4 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | NF2 | 25361965 | interaction type | N/A | PTMCode2 |
| NF2 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | SRC | 25361965 | interaction type | N/A | PTMCode2 |
| SRC | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | MSN | 25361965 | interaction type | N/A | PTMCode2 |
| MSN | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | PTPRC | 25361965 | interaction type | N/A | PTMCode2 |
| PTPRC | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | FYN | 25361965 | interaction type | N/A | PTMCode2 |
| FYN | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | MMP9 | 25361965 | interaction type | N/A | PTMCode2 |
| MMP9 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| CD44 | SPP1 | 25361965 | interaction type | N/A | PTMCode2 |
| SPP1 | CD44 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDC73 | CD44 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | CD44 | 25348397 | N/A | physical interaction | ComPPI |
| DYNLL1 | CD44 | 25348397 | N/A | physical interaction | ComPPI |
| WASL | CD44 | 17092940 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| COL1A2 | CD44 | 14525934 1730778 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| SRGN | CD44 | 14525934 25348397 27898060 9334256 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| TRAF6 | CD44 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| HYAL2 | CD44 | 15090545 24234451 25348397 25864644 27898060 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct,OmniPath |
| CD44 | MMP7 | 11825873 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD44 | CD4 | 14525934 25348397 7539755 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CD44 | TGFBR2 | 12145287 14525934 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CD44 | VAV2 | 11606575 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CD44 | ERBB4 | 11825873 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD44 | TIAM1 | 10636882 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD44 | DMP1 | 11825898 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CD44 | ARHGEF1 | 12748184 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CD44 | NF2 | 12356905 14525934 17891137 24912773 25348397 27898060 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| CD44 | PKN1 | 14525934 15123640 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CD44 | ANK1 | 14525934 15051494 25348397 27898060 7505012 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,OmniPath |
| CD44 | ARHGEF12 | 14525934 16565089 25348397 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD |
| CD44 | GARS1 | 15452148 25348397 27898060 | N/A | two hybrid,in vivo | ComPPI,OmniPath |
| CD44 | MADCAM1 | 2474557 25348397 27898060 | N/A | in vitro | ComPPI,OmniPath |
| CD44 | COL1A1 | 14525934 1730778 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
| CD44 | COL14A1 | 14525934 25348397 27898060 8986622 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,OmniPath |
| CD44 | MMP9 | 10652271 14525934 17912438 25348397 27898060 | N/A | experimental interaction detection,in vivo | ComPPI,HPRD,OmniPath |
| CD44 | EZR | 12032545 12370738 14525934 20711218 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD,IntAct,OmniPath |
| CD44 | CSK | 11084024 14525934 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| CD44 | HBEGF | 14525934 25348397 7532176 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CD44 | SELE | 11402070 14525934 19889975 24234451 25348397 27898060 | physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct,OmniPath |
| CD44 | EGFR | 12093135 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CD44 | FGF2 | 14525934 25348397 7532176 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| CD44 | FYN | 14525934 25348397 9573028 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD44 | CD74 | 14525934 24234451 25348397 27898060 29190904 8343954 | colocalization,physical association | anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,confocal microscopy | ComPPI,HPRD,IntAct,OmniPath |
| CD44 | IGFBP3 | 12127836 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| CD44 | LCK | 14525934 25348397 8576267 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| CD44 | SPP1 | 10657301 12377945 14525934 20146103 20549562 24234451 25348397 | colocalization,physical association | experimental interaction detection,fluorescence microscopy,in vitro,proximity ligation assay | ComPPI,HPRD,IntAct |
| CD44 | VCAN | 10950950 14525934 25348397 | N/A | experimental interaction detection,physical interaction,solid phase assay | ComPPI,HPRD |
| CD44 | TGFBR1 | 12145287 14525934 25348397 | N/A | experimental interaction detection,physical interaction | ComPPI,HPRD |
| CD44 | FN1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | ERBB2 | 17092940 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | SRC | 11084024 21701559 25348397 27898060 9519902 | N/A | physical interaction | ComPPI,OmniPath |
| CD44 | PTPRC | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | MSN | 23855374 24234451 25348397 27898060 | colocalization,physical association | anti bait coimmunoprecipitation,physical interaction,confocal microscopy | ComPPI,IntAct,OmniPath |
| CD44 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | PRKCZ | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | ITGB1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FLOT2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CAV1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | EP300 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | STAT3 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SLC3A2 | 21397861 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | FMNL1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | VHL | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | BAG1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | DPP8 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | ABCE1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CRYBG1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | DBN1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FLNA | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | MYH9 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SYNPO | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | LIMA1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | MYO19 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SQSTM1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | CHERP | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | PHRF1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CTDSPL | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GMEB2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GMEB1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | DHRS2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | TCAF2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SLC39A9 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | AMPD2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SNX33 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CAMKV | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | ATG9A | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | PRDM10 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | C17ORF80 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | SNX18 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FGFR2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FGFRL1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | VANGL1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | PARP2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | TEFM | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | LAMA3 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | MTCH2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | HADHB | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GTF3C2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CDC40 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GTF3C3 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | AQR | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GTF3C1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | GTF3C6 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | HADHA | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | TMEM160 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | OSBPL8 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | TNPO2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | LEMD3 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | LGALS1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | RBM22 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | VANGL2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | MBOAT7 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | ISY1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | NIPSNAP2 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CD9 | 25348397 | N/A | coimmunoprecipitation,physical interaction | ComPPI |
| CD44 | ITGA4 | 21257905 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | SCYL3 | 12651155 24234451 25348397 | physical association | confocal microscopy | ComPPI,IntAct |
| CD44 | ACTR2 | 17092940 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CD44 | ACTR3 | 17092940 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| CD44 | SLC7A11 | 21397861 24234451 25348397 27898060 | colocalization,association,physical association | anti bait coimmunoprecipitation,fluorescence microscopy | ComPPI,IntAct,OmniPath |
| CD44 | MET | 22897854 24234451 25348397 | physical association | cross-linking study | ComPPI,IntAct |
| CD44 | HGF | 22897854 24234451 25348397 | physical association | cross-linking study | ComPPI,IntAct |
| CD44 | LAMP1 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| IQGAP1 | CD44 | 25348397 | N/A | physical interaction | ComPPI |
| XAB2 | CD44 | 25348397 | N/A | physical interaction | ComPPI |
| PRKCI | CD44 | 25348397 | N/A | physical interaction | ComPPI |
| HMMR | CD44 | 12939665 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| ATF2 | CD44 | 22304920 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD44 | CD44 | 11825873 14525934 | N/A | experimental interaction detection | HPRD |
| MMP1 | CD44 | 11381077 14525934 27898060 | N/A | experimental interaction detection | HPRD,OmniPath |
| PRKACA | CD44 | 16785995 27898060 | stimulant | N/A | OmniPath |
| PRKCA | CD44 | 12032545 22865879 27898060 | N/A | N/A | OmniPath |
| PLK1 | CD44 | 12032545 27898060 | N/A | N/A | OmniPath |
| FN1 | CD44 | 1730778 27898060 | stimulant | N/A | OmniPath |
| HAS2 | CD44 | 1694723 27898060 | stimulant | N/A | OmniPath |
| TLR2 | CD44 | 18322236 27898060 | N/A | N/A | OmniPath |
| VIM | CD44 | 22216242 27898060 | N/A | N/A | OmniPath |
| HGF | CD44 | 10037743 27898060 | N/A | N/A | OmniPath |
| CAMK2A | CD44 | 11463356 1281449 19582779 27898060 9580567 | stimulant | N/A | OmniPath |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B878D | CD44 | 27087310 | direct interaction,inhibition | N/A | NPInter |